RESUMEN
BACKGROUND: Despite numerous studies indicating a high prevalence of herpesviruses in both apical and marginal periodontitis samples, their exact role in the pathogenesis of a periodontal disease is still unclear. OBJECTIVE: This umbrella review aimed to summarize data on herpesviruses detection in marginal periodontitis (MP) and apical periodontitis of endodontic origin (APEO) samples. METHODS: The study protocol has been drafted a priori and registered to the International Prospective Register of Systematic Reviews (PROSPERO) (CRD42020215922). The literature search was conducted using the following electronic databases: Clarivate Analytics' Web of Science, Scopus, PubMed and Cochrane Database of Systematic Reviews, from inception to October 2020, with no language restrictions. Systematic reviews with or without meta-analysis that evaluated the association between the occurrence of herpesviruses and different forms of periodontal diseases were included. Other types of studies, including narrative reviews, were excluded. Two reviewers independently performed a literature search, data extraction, and quality assessment of included studies. Any disagreements or doubts were resolved by a third reviewer. The quality of the reviews was assessed using the AMSTAR 2 tool (A measurement tool to assess systematic reviews). RESULTS: Six systematic reviews were included in the current review. One was graded as high quality, another one was graded as moderate quality, whereas the other four were graded as critically low-quality reviews. The presence of herpesviruses in subgingival samples was associated with an increased risk of MP, supported by the corresponding meta-analyses. Although the association was strong (OR > 3.0), the confidence intervals were wide, heterogeneity was significant, and studies were of small sample size. In addition, publication bias was detected. Contrary, data from systematic reviews that assessed APEO and herpesviruses did not show any significant associations. CONCLUSIONS: Low-quality studies with high uncertainty suggest a strong association between herpesviruses and MP, but not with APEO.
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Periodontitis Periapical , Periodontitis , Bases de Datos Factuales , Humanos , Periodontitis Periapical/epidemiología , Periodontitis/epidemiología , Simplexvirus , Revisiones Sistemáticas como AsuntoRESUMEN
Tobacco smoking is responsible for several health problems, including mouth diseases. The aim of the present study was to establish the association between smoking and dental status and self-perceived oral health in a large group of elderly Colombian adults. Analysis of 18,937 survey records of participants aged ≥ 60 years old was conducted. Information regarding age, sex, skin color, socioeconomic level, education, marital status, denture use, partial tooth loss or edentulism, Geriatric Oral Health Assessment Index (GOHAI) and tobacco smoking was retrieved from the database. A descriptive analysis and multivariate logistic regression analysis were performed. Half of the participants were edentulous in the maxilla while mandibular teeth were more frequently retained in more than 60% of the participants. After adjusting for sex and age, smoking consistently increased the odds of partial or complete edentulism in the maxilla (OR 1.05; 95% CI 1.02-1.09) and mandible (OR 1.04; 95% CI 1.00-1.08). Nonetheless, the increase in the odds in the mandible was not statistically significant. The habit of smoking was associated with increased tooth loss that in the long-term may result in poor oral health affecting the quality of life of elderly people.
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Envejecimiento/psicología , Boca Edéntula/etiología , Salud Bucal/estadística & datos numéricos , Calidad de Vida/psicología , Fumar Tabaco/efectos adversos , Pérdida de Diente/etiología , Anciano , Anciano de 80 o más Años , Colombia , Estudios Transversales , Atención Odontológica/psicología , Escolaridad , Evaluación Geriátrica , Humanos , Masculino , Persona de Mediana Edad , Boca Edéntula/psicología , Autoimagen , Encuestas y Cuestionarios , Pérdida de Diente/psicologíaRESUMEN
BACKGROUND AND OBJECTIVE: Human cytomegalovirus (HCMV) has been associated with periodontitis and apical periodontitis. The objective of this systematic review was to evaluate the association between HCMV and periodontitis, and apical periodontitis of endodontic origin. MATERIAL AND METHODS: A systematic review was performed according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) statement guidelines and registered in the International prospective register of systematic reviews (PROSPERO). The search for potential studies was performed in MEDLINE via PubMed, Scopus, and SciELO. A quality assessment of the studies, publication bias analysis, and meta-analysis was performed. The results are presented in odds ratio with 95% confidence interval with the corresponding Forest plot. Sensitivity analysis was performed to evaluate the consistency of the results. RESULTS: Thirty-two studies were included in the quantitative and qualitative analyses. Of these, 26 were in periodontitis patients and 6 in apical periodontitis patients. Forest plot of combined studies revealed significant increased odds for periodontitis when subgingival HCMV was detected (OR 5.31; 95% CI 3.15-8.97). Sensitivity analysis based on quality of the included studies, showed consistent results. In contrast, the odds ratio for apical periodontitis when HCMV was detected from apical lesions was not statistically significant (OR 3.65; 95% CI 0.49-27.10). CONCLUSIONS: The results from the meta-analysis indicate that HCMV is significantly associated with periodontitis. In contrast, HCMV infection is not associated with apical periodontitis.
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Infecciones por Citomegalovirus , Periodontitis Periapical , Periodontitis , Citomegalovirus , Infecciones por Citomegalovirus/complicaciones , Humanos , Periodontitis Periapical/virología , Periodontitis/virologíaRESUMEN
OBJECTIVES: Scientific literature has established that the periodontal condition during pregnancy could be associated with obstetric/neonatal morbidity, and these effects have an important relationship with problems during childhood and cardiovascular disease in adulthood. This umbrella review aimed to summarize the results about the association between maternal periodontitis and obstetric complications (low birth weight, preterm delivery, and preeclampsia) and identify the gaps in the scientific literature. METHODS: An umbrella review of systematic reviews with or without meta-analysis was performed. Quality evaluation and descriptive analysis of the characteristics of the included studies were conducted. RESULTS: Nineteen systematic reviews/meta-analyses were considered. In total, the systematic reviews included 99 observational studies. Most of the reviews established an association between maternal periodontitis and a higher risk of low birth weight, preterm delivery, and preeclampsia. The magnitude and statistical significance of this relationship are influenced by the context in which the studies have been conducted. Gaps were identified in the definition/evaluation of periodontal disease, criteria of gestational age for study purposes, and potential confounders, among others. CONCLUSIONS: Although scientific literature has established an association among the analyzed pathologies, conceptual and methodological gaps were identified, and they should be considered as integral components when this association is investigated.
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Enfermedades Periodontales , Periodontitis , Nacimiento Prematuro , Adulto , Niño , Femenino , Humanos , Recién Nacido de Bajo Peso , Recién Nacido , Embarazo , Resultado del EmbarazoRESUMEN
OBJECTIVE: In the recent years, efforts have been made to reduce epidemiologic indicators of periodontal disease in pregnant women. This umbrella review aims to analyze the systematic reviews/meta-analyses investigating the effect of periodontal therapy in pregnant women on the frequency of obstetric complications (low birth weight, preterm delivery, and preeclampsia) and to identify the gaps in the scientific literature. METHODS: A systematic review of systematic reviews with and without meta-analysis of intervention studies was conducted. Quality evaluation and qualitative analysis of the reviews were performed. RESULTS: A total of 223 articles were obtained, and 18 of them were included in the analysis, 13 articles included meta-analysis, where 11 were of high quality and 7 of medium quality according to the Assessing the Methodological Quality of Systematic Reviews (AMSTAR) guide. These systematic reviews/meta-analyses included a total of 19 studies (17 randomized clinical trials). Descriptive systematic reviews showed that periodontal therapy has positive effects on reducing the frequency of adverse pregnancy outcomes. In systematic reviews with meta-analysis, overall effect estimators were not significant, although a reduction in the incidence of obstetric complications was observed. Subgroup analysis resulted in significant effects, depending on sociodemographic conditions. CONCLUSIONS: Differential findings are not enough to demonstrate that there is a significant reduction in the frequency of adverse pregnancy outcomes in pregnant women receiving periodontal therapy. Possible explanations are related to factors such as the type of studies analyzed, indicator of obstetric complication considered, and specific variables included in the analysis. Many systematic reviews did not address publication bias and did identify gaps in knowledge that require further clarification.
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Enfermedades Periodontales , Complicaciones del Embarazo , Nacimiento Prematuro , Atención Odontológica , Femenino , Humanos , Recién Nacido de Bajo Peso , Recién Nacido , Enfermedades Periodontales/terapia , Embarazo , Complicaciones del Embarazo/terapia , Resultado del EmbarazoRESUMEN
ARTICLE TITLE AND BIBLIOGRAPHICAL INFORMATION: Treatment of periodontal disease for glycaemic control in people with diabetes mellitus. Simpson TC, Weldon JC, Worthington HV, Needleman I, Wild SH, Moles DR, Stevenson B, Furness S, Iheozor-Ejiofor Z. Cochrane Database Syst Rev 2015;11:CD004714. SOURCE OF FUNDING: This project was supported by the NIHR, via Cochrane Infrastructure funding to the Cochrane Oral Health Group, School of Dentistry, University of Manchester (UK), Manchester Academic Health Sciences Centre (UK), and the National Institute for Health Research (UK) TYPE OF STUDY/DESIGN: Systematic review with meta-analysis.
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Glucemia , Periodontitis , Diabetes Mellitus Tipo 2 , Humanos , Enfermedades PeriodontalesRESUMEN
Human periodontitis is associated with a wide range of bacteria and viruses and with complex innate and adaptive immune responses. Porphyromonas gingivalis, Tannerella forsythia, Aggregatibacter actinomycetemcomitans, Treponema denticola, cytomegalovirus and other herpesviruses are major suspected pathogens of periodontitis, and a combined herpesvirus-bacterial periodontal infection can potentially explain major clinical features of the disease. Cytomegalovirus infects periodontal macrophages and T-cells and elicits a release of interleukin-1ß and tumor necrosis factor-α. These proinflammatory cytokines play an important role in the host defense against the virus, but they also have the potential to induce alveolar bone resorption and loss of periodontal ligament. Gingival fibroblasts infected with cytomegalovirus also exhibit diminished collagen production and release of an increased level of matrix metalloproteinases. This article reviews innate and adaptive immunity to cytomegalovirus and suggests that immune responses towards cytomegalovirus can play roles in controlling, as well as in exacerbating, destructive periodontal disease.
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Infecciones por Citomegalovirus/inmunología , Citomegalovirus/inmunología , Periodontitis/virología , Inmunidad Adaptativa/inmunología , Interacciones Huésped-Patógeno/inmunología , Humanos , Evasión Inmune/inmunología , Inmunidad Innata/inmunología , Mediadores de Inflamación/inmunología , Periodontitis/inmunologíaRESUMEN
BACKGROUND: Down syndrome (DS) is distinguished by cognitive disability, a concave profile, and systemic complications. Oral diseases have been reported to be common in DS patients. OBJECTIVE: To investigate the association between DS and periodontal diseases. METHODS: Two independent reviewers searched six bibliographic databases up to January 2023 and used additional search methods to identify published studies on gingivitis or periodontitis in people with and without DS. Meta-analysis, risk of bias, sensibility analysis, publication bias, and evidence grading were all carried out. RESULTS: Twenty-six studies were included for analysis. There was a tendency for increased plaque accumulation, periodontal probing, periodontal attachment level, bleeding on probing and indices in DS individuals. Meta-analysis of 11 studies showed a significant association between DS and periodontitis (OR 3.93; 95% CI 1.81-8.53). Probing depth was significantly high in individuals with DS as compared to controls (mean difference 0.40 mm; 95% CI 0.09-0.70). Gingivitis was significantly associated (OR 1.93; 95% CI 1.09-3.41) with DS in four studies. The evidence was classified as 'moderate certainty'. CONCLUSION: Medium/low-quality studies demonstrate that Down syndrome is strongly associated with periodontitis and moderately associated with gingivitis.
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Placa Dental , Síndrome de Down , Gingivitis , Enfermedades Periodontales , Periodontitis , Humanos , Síndrome de Down/complicaciones , Síndrome de Down/epidemiología , Enfermedades Periodontales/complicaciones , Enfermedades Periodontales/epidemiología , Gingivitis/complicaciones , Gingivitis/epidemiologíaRESUMEN
BACKGROUND AND OBJECTIVE: Periodontitis and rheumatoid arthritis (RA) have been associated in a bidirectional way. The objective of this study was to determine the association between clinical parameters of periodontitis and RA. MATERIALS AND METHODS: Seventy-five (75) participants distributed in 3 groups (21 patients with periodontitis without RA, 33 patients with periodontitis with RA and 21 patients with reduced periodontium with RA) were included in this cross-sectional study. A full periodontal and medical examination was performed in each patient. Additionally, subgingival plaque samples for the detection of Porphyromonas gingivalis (P. gingivalis) and blood samples for biochemical markers of RA were also taken. Logistic regression analysis adjusted for confounding variables, Spearman's rank correlation coefficient and a linear multivariate regression were used to analyze the data. RESULTS: Patients with RA presented less severity of periodontal parameters. The highest levels of anti-citrullinated protein antibodies were detected in non-periodontitis patients with RA. Covariates such as age, P. gingivalis, diabetes, smoking, osteoporosis and use of medication were not associated with RA. All periodontal variables and P. gingivalis expressed a negative correlation with biochemical markers of RA (P<0.05). CONCLUSIONS: Periodontitis was not associated with RA. Furthermore, there was no correlation between periodontal clinical parameters and biochemical markers of RA.
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Artritis Reumatoide , Periodontitis , Humanos , Estudios Transversales , Artritis Reumatoide/complicaciones , Porphyromonas gingivalis , BiomarcadoresRESUMEN
BACKGROUND: Chronic health conditions and socioeconomic problems that affect the well-being and life expectancy of older adults are common. The objective of this cross-sectional study was to analyze the association between sociodemographic variables, oral conditions, and general health and the biomarkers of older adults using machine learning (ML). METHODS: A total of 15,068 surveys from the national study of Health, Well-Being and Aging (Salud, Bienestar y Envejecimiento) data set were used for this secondary analysis. Of these, 3,128 people provided blood samples for the analysis of blood biomarkers. Sociodemographic, oral health, and general health variables were analyzed using ML and logistic regression. RESULTS: The results of clustering analysis showed that dyslipidemia was associated with poor oral condition, lower socioeconomic status, being female, and low education. The self-perception of oral health in older adults was not associated with the presence of teeth, blood biomarkers, or socioeconomic variables. However, the necessity of replacing a dental prosthesis was associated with the lowest self-perception of oral health. Edentulism was associated with being female, increased age, and smoking. CONCLUSIONS: Socioeconomic and educational disparities, sex, and smoking are important factors for tooth loss and suboptimal blood biomarkers in older adults. ML is a powerful tool for identifying potential variables that may aid in the prevention of systemic and oral diseases in older adults, which would improve geriatric dentistry. PRACTICAL IMPLICATIONS: These findings can help the academic community identify critical sociodemographic and clinical factors that influence the process of healthy aging and serve as a useful guide to enhance health care policies and geriatric oral health care services.
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Enfermedades de la Boca , Humanos , Femenino , Anciano , Masculino , Colombia/epidemiología , Estudios Transversales , Salud Bucal , Aprendizaje Automático , Factores SocioeconómicosRESUMEN
BACKGROUND: Rheumatoid arthritis (RA) and periodontitis (PD) are chronic diseases that are associated with connective tissue and bone destruction, which affects the quality of life of the people suffering from these conditions. The identification of social conditions and the determinants of RA and PD would permit the elaboration of policies and strategies based on social reality. OBJECTIVES: The aim of the present study was to identify the relationship between oral health-related quality of life (OHRQoL) and the indicators of general health and oral health in patients with RA. MATERIAL AND METHODS: A cross-sectional study involving 59 patients with RA was conducted between 2019 and 2020. Demographic, general health, periodontal, and oral health parameters were collected. In addition, the Oral Health Impact Profile-14 (OHIP-14) questionnaire was administered to each patient. A description of the OHIP-14 dimensions according to different variables was performed. The relationship between OHRQoL and general/oral health indicators was analyzed with logistic and linear regression analyses. RESULTS: The highest OHIP-14 scores were found in people that were 60 years of age and over, single, had low educational achievements, a low socioeconomic status, were unemployed, and had no health affiliation. In the adjusted model, the prevalence of the impact on OHRQoL was 1.34 (1.10-5.29) times greater in those with erosive RA than in those without, and 2.22 (1.16-29.50) times greater in those who self-reported morning stiffness. Regarding the stage of PD, those with stage IV had a prevalence of the impact on the OHRQoL of 70%, an average extent of 3.4 ±4.5 and a severity score of 11.5 ±22.0, with statistically significant differences. CONCLUSIONS: The dimensions with the greatest impact on the OHRQoL of patients were physical pain, discomfort and psychological disability. The type of RA and the severity of PD are indicators of worse scores on the OHRQoL scale.
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Artritis Reumatoide , Periodontitis , Humanos , Calidad de Vida , Estudios Transversales , Salud Bucal , Artritis Reumatoide/complicacionesRESUMEN
Background: The new classification of periodontal diseases introduced a new set of rules for periodontal diagnosis. The objective of this study was to develop and test the implementation of a mobile device application for periodontal diagnosis. Material and Methods: An integral algorithm that included periodontal health / related conditions and periodontitis was developed based on the classification of periodontal diseases of 2018. A mobile application for Android implementing the algorithm was developed using the framework MIT App Inventor. Once the app was debugged for glitches and performance of the algorithm, it was tested with 20 voluntary dental students, postgraduate students of periodontology, and professors in an academic setting. Participants were asked to determine the diagnosis of 10 predetermined clinical cases using two strategies: diagnosis based on knowledge and with the PerioSmart app. The results were tabulated, and the concordance rate was calculated. Results: In general, the use of the PerioSmart application had a better concordance rate than diagnosis based on knowledge. In particular, the mobile app was better in determining the type of diagnosis, stage/grade of periodontitis, and with better efficiency. Conclusions: The mobile device application demonstrated efficiency and good concordance rate and therefore can improve the periodontal diagnosis. Key words:Mobile application, periodontal diagnosis, periodontitis, gingivitis.
RESUMEN
Millions of individuals are affected by early onset periodontal disease in Latin America, a continent that includes more than 20 countries. The decision-makers claim that the disease is not commonly encountered. In 2009, 280,919 authorized immigrants were registered in the United States versus 5,460,000 unauthorized (2,600,000 in California). The objective of the present article is to raise awareness about the high prevalence of the disease among Latin Americans and the good prognosis of preventive measures associated with minimal financial cost.
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Aculturación , Enfermedades Periodontales/epidemiología , Ajuste Social , Adolescente , Edad de Inicio , Niño , Comorbilidad , Emigrantes e Inmigrantes/estadística & datos numéricos , Gingivitis/epidemiología , Gingivitis/etnología , Gingivitis/psicología , Hispánicos o Latinos/estadística & datos numéricos , Humanos , América Latina/etnología , Pérdida de la Inserción Periodontal/epidemiología , Pérdida de la Inserción Periodontal/etnología , Pérdida de la Inserción Periodontal/psicología , Enfermedades Periodontales/etnología , Enfermedades Periodontales/psicología , Periodontitis/epidemiología , Periodontitis/etnología , Periodontitis/psicología , Estados Unidos/epidemiología , Adulto JovenRESUMEN
BACKGROUND: At present, there are limited studies on how tooth whitening procedures are applied in orthodontic patients. Therefore, the objective of this study was to assess the perception of tooth whitening practices during and after orthodontic treatment. MATERIAL AND METHODS: A survey of orthodontists in Medellín (Colombia) between January and October 2020 was carried out. The survey instrument was developed to obtain information regarding the perception and practices of tooth whitening during and after orthodontic treatment. RESULTS: 133 orthodontists with a mean age of 41,6 years old participated in the survey. Over 60% of participants reported >6 years of experience as orthodontist. The majority (99,2%) reported that their patients request tooth whitening. Of these, 71,2% refer the patient to another dental professional for the procedure while 28,8% administers it. More than half of orthodontists reported that their patients request dental whitening during orthodontic treatment. The majority (>90%) of orthodontists do not recommend tooth whitening during orthodontic treatment. Furthermore, >80% consider that tooth whitening is best recommended after brackets have been removed. CONCLUSIONS: Requests for tooth whitening from orthodontic patients is very frequent and most orthodontists favor the referral to another dental professional for the procedure. The majority do not recommend tooth whitening during orthodontic treatment and prefer waiting 1 to 3 months after brackets removal for the procedure. Key words:Tooth whitening, orthodontic treatment, brackets.
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BACKGROUND: Excessive occlusal forces and occlusal trauma have been implicated as co-destructive factors for periodontitis in animal models. The objective of this study was to assess the association between occlusal trauma and periodontitis. METHODS: A total of 167 cases and 205 controls were included for analysis. Occlusal trauma was the exposures of interest and was registered for cases and controls. Additional clinical co-variables were registered as well for further analysis. The association of the exposure and periodontitis was determined by the odds ratio and logistic regression analysis adjusted for confounders. RESULTS: Amalgam restorations, pathogenic occlusion and occlusal trauma were more frequent in cases as compared to controls (P ≤ 0.05). The distribution of pathogenic occlusion and occlusal trauma was similar according to the stage and class of periodontitis. Logistic regression analysis showed a significant association for cigarette smoking, systemic conditions, amalgam restorations, pathogenic occlusion, and occlusal trauma with periodontitis (P ≤ 0.05). After adjusting for confounding variables in the model, amalgam restorations and occlusal trauma remained strongly associated with periodontitis (P ≤ 0.05). CONCLUSIONS: Occlusal trauma is strongly associated with periodontitis. Additional long-term prospective studies are necessary to further understand the impact of the occlusal condition and periodontitis.
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Oclusión Dental Traumática , Periodontitis , Animales , Estudios de Casos y Controles , Oclusión Dental Traumática/complicaciones , Oclusión Dental Traumática/epidemiología , Periodontitis/complicaciones , Periodontitis/epidemiología , Estudios Prospectivos , Estudios RetrospectivosRESUMEN
Background: periodontal therapy has been suggested to have systemic effects. However, studies of periodontal therapy in rheumatoid arthritis patients have produced controversial results. Aim: To compare the effects of nonsurgical periodontal therapy on biochemical markers of rheumatoid arthritis and periodontal parameters in patients with and without rheumatoid arthritis. Methods: a prospective before-and-after study was conducted that included 21 participants without and 29 participants with rheumatoid arthritis. Periodontal parameters, Porphyromonas gingivalis detection, C-reactive protein, rheumatoid factor and anti-citrullinated protein antibodies were measured at baseline and three months after nonsurgical periodontal therapy and the changes were statistically assessed. Results: In general, both groups presented statistically significant improvement in periodontal parameters (p<0.05). There was an increase in the counts of P. gingivalis in both groups at three months. In addition, there was a reduction in levels of anti-citrullinated protein antibodies and rheumatoid factor in participants with rheumatoid arthritis. In contrast, C-reactive protein levels increased in both groups but were higher in the rheumatoid arthritis group. Periodontal parameters in rheumatoid arthritis participants under disease-modifying antirheumatic drugs presented a slightly higher improvement (p <0.05). Conclusions: Nonsurgical periodontal therapy has similar improvements in periodontal parameters in patients with and without rheumatoid arthritis. In addition, nonsurgical periodontal therapy may benefit serum levels of anti-citrullinated protein antibodies and rheumatoid factors in patients with rheumatoid arthritis. NCT04658615.
Antecedentes: se ha sugerido que la terapia periodontal tiene efectos sistémicos. Sin embargo, los estudios de la terapia periodontal en pacientes con artritis reumatoide han producido resultados controvertidos. Objetivo: comparar los efectos de la terapia periodontal no quirúrgica sobre los marcadores bioquímicos de la artritis reumatoide y los parámetros periodontales en pacientes con y sin artritis reumatoide. Métodos: se realizó un estudio prospectivo de antes y después que incluyó a 21 participantes sin artritis reumatoide y 29 participantes con artritis reumatoide. Se midieron los parámetros periodontales, detección de Porphyromonas gingivalis, proteína C reactiva, factor reumatoide y anticuerpos anti-proteína citrulinada al inicio del estudio y tres meses después de la terapia periodontal no quirúrgica y los cambios se evaluaron estadísticamente. Resultados: En general, ambos grupos presentaron mejoría estadísticamente significativa en los parámetros periodontales (p <0.05). Hubo un aumento en los recuentos de P. gingivalis en ambos grupos a los tres meses. Además, hubo una reducción en los niveles de anticuerpos anti-proteína citrulinada y factor reumatoide en participantes con artritis reumatoide. Por el contrario, los niveles de proteína C reactiva aumentaron en ambos grupos, pero fueron más altos en el grupo de artritis reumatoide. Los parámetros periodontales en los participantes con artritis reumatoide bajo fármacos antirreumáticos modificadores de la enfermedad presentaron una mejoría ligeramente mayor (p <0.05). Conclusiones: La terapia periodontal no quirúrgica tiene mejoras similares en los parámetros periodontales en pacientes con y sin artritis reumatoide. Además, la terapia periodontal no quirúrgica puede beneficiar los niveles séricos de anticuerpos anti-proteína citrulinada y factor reumatoide en pacientes con artritis reumatoide. NCT04658615.
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Artritis Reumatoide , Factor Reumatoide , Anticuerpos Antiproteína Citrulinada/uso terapéutico , Artritis Reumatoide/tratamiento farmacológico , Proteína C-Reactiva/análisis , Proteína C-Reactiva/uso terapéutico , Humanos , Porphyromonas gingivalis , Estudios ProspectivosRESUMEN
Little attention has been directed toward evidence that an early-in-life oral infection with the potential to reach epidemic proportions is threatening the health of youths throughout world. Health professionals and the public seem unaware that the silent disease process of early-in-life periodontal infection is targeting thousands of children and young adults, their smiles, and, consequently, their emotional and psychologic lives. Yet, the literature is replete with reports that many periodontopathic microorganisms are multiplying at an alarming rate with a serious impact on youths in many cities, towns, and villages throughout the globe. However, clinical measurement of reported periodontal disease has been fraught with problems that have confused and clouded messages to policymakers in government and health professionals in treatment settings. The aim of this article is to help raise the level of awareness so that those who have the power and knowledge can appropriately address the suffering of the youngest members of societies.
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Salud Global , Enfermedades Periodontales/complicaciones , Sonrisa , Adolescente , Periodontitis Agresiva/complicaciones , Periodontitis Agresiva/inmunología , Periodontitis Agresiva/psicología , Niño , Humanos , Enfermedades Periodontales/inmunología , Enfermedades Periodontales/psicología , Sonrisa/psicología , Pérdida de Diente/etiología , Pérdida de Diente/psicología , Adulto JovenRESUMEN
OBJECTIVE: Occlusal adjustment is commonly recommended for patients with periodontitis and traumatic occlusion. The objective of this systematic review was to analyze available evidence for the association between traumatic occlusal forces and periodontitis. METHODS: Two focused questions were proposed: What is the effect of traumatic occlusal forces on periodontal parameters in patients with and without periodontitis? And what is the effect of occlusal interventions on periodontal parameters in patients with periodontitis? A systematic review of clinical and observational studies was performed and presented in narrative form. RESULTS: After title and abstract review a total of 30 articles were retrieved and of these 14 full-text articles were retrieved for analysis. Two RCTs, 1 cohort, 4 retrospective and 7 cross-sectional studies were included. Cross-sectional studies reported a significant association between occlusal discrepancies and probing depth and clinical attachment level. However, the magnitude of the effect is negligible when groups with and without occlusal discrepancies are compared. Intervention studies reported a minimal effect on probing depth and clinical attachment level after occlusal adjustment in patients with periodontitis as compared to teeth without occlusal adjustment. CONCLUSIONS: Available human studies showed that there is limited evidence that traumatic occlusion is associated with periodontitis and to support the implementation of occlusal adjustment to significantly improve the periodontal condition in patients with periodontitis.
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Fuerza de la Mordida , Periodontitis , Estudios Transversales , Humanos , Ajuste Oclusal , Estudios RetrospectivosRESUMEN
AIM: To investigate the subgingival microbiota of distinct periodontitis patient populations, in Chile, Colombia and Spain, using identical clinical and bacteriological methods. MATERIAL AND METHODS: In this multicentre study, 114 chronic periodontitis patients were selected. Patients were examined using an identical clinical protocol and pooled subgingival samples were obtained from each patient. Samples were processed in the three laboratories by means of culturing under identical clinical and microbiological protocols. Total anaerobic counts and frequency of detection and proportions of nine periodontal pathogens were calculated. Variables were analysed by means of anova, chi(2), Kruskal-Wallis and Dunn's multiple comparison tests. RESULTS: The Colombian population demonstrated greater severity of periodontitis, with significantly deeper mean probing pocket depth, and had a significantly lower percentage of current smokers. When comparing samples from the three patient populations, the total counts were significantly higher in the Colombian patients. The numbers of putative pathogens differed among groups. Tannerella forsythia was found less frequently in Chilean samples, while Parvimonas micra and enteric rods differed significantly among the three population groups. CONCLUSION: Significant differences among Chile, Colombia and Spain existed regarding the frequency and proportions of specific periodontal pathogens in the subgingival microbiota of periodontitis patients.
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Actinomyces/aislamiento & purificación , Periodontitis/microbiología , Porphyromonas gingivalis/aislamiento & purificación , Prevotella intermedia/aislamiento & purificación , Adulto , Chile , Enfermedad Crónica , Colombia , Recuento de Colonia Microbiana , Métodos Epidemiológicos , Femenino , Humanos , Masculino , Bolsa Periodontal/microbiología , Fumar/epidemiología , EspañaRESUMEN
BACKGROUND: Viruses from the Herpesviridae family may be implicated in the pathogenesis of periodontal disease. The aim of this investigation was to compare the subgingival frequency of human cytomegalovirus (HCMV) in subjects affected by periodontitis to periodontally healthy subjects and to assess the correlation of HCMV with periodontal clinical parameters and periodontopathic bacteria. METHODS: Thirty subjects with periodontitis (20 with chronic periodontitis and 10 with aggressive periodontitis) were included in the study. A group of 22 periodontally healthy individuals served as controls. Clinical periodontal parameters of probing depth (PD) and clinical attachment level (CAL) were recorded using a computerized periodontal probe. Subgingival plaque samples were processed for viral identification by nested polymerase chain reaction and bacterial identification by culture. Clinical periodontal parameters, frequency of detection of HCMV, and microbial composition were compared between the groups using the two-tailed Student t, chi(2), and Mann-Whitney tests. Logistic and linear regression analyses were performed to measure the association between virus-bacterial coinfection and clinical parameters (P < or =0.05). RESULTS: HCMV detection was more prevalent (P < or =0.05) in periodontally diseased subjects compared to healthy ones. Furthermore, in all groups, PD and CAL were increased in HCMV-positive sites. In the periodontitis groups, higher frequencies and levels of specific periodontopathic bacteria were detected in HCMV-positive sites. CONCLUSIONS: HCMV detection in periodontal pockets was associated with higher levels of periodontopathic bacteria and increased PD and CAL at sampled sites. HCMV/bacteria coinfection may be an important factor in periodontal destruction.