RESUMEN
We report a lateral rectus muscle paralysis occurring 2 weeks after initiation of an interferon-α and ribavirin treatment in a patient with human immunodeficiency virus (HIV) and hepatitis C virus (HCV) virus co-infection. This patient presented with horizontal diplopia that appeared rapidly and without any other neurological symptoms. Symptoms fully resolved with treatment interruption without any ophthalmological sequelae. This side effect is rare and has never been reported in a HIV-HCV co-infected patient.
Asunto(s)
Enfermedades del Nervio Abducens/inducido químicamente , Antivirales/efectos adversos , Infecciones por VIH/tratamiento farmacológico , Hepatitis C Crónica/tratamiento farmacológico , Interferón-alfa/efectos adversos , Polietilenglicoles/efectos adversos , Ribavirina/efectos adversos , Enfermedades del Nervio Abducens/diagnóstico , Adulto , Antivirales/uso terapéutico , Ojo/efectos de los fármacos , Ojo/fisiopatología , Infecciones por VIH/virología , Hepatitis C Crónica/virología , Humanos , Interferón-alfa/uso terapéutico , Masculino , Músculo Esquelético/efectos de los fármacos , Músculo Esquelético/fisiopatología , Polietilenglicoles/uso terapéutico , Proteínas Recombinantes/efectos adversos , Proteínas Recombinantes/uso terapéutico , Ribavirina/uso terapéuticoRESUMEN
We report an unusual case of a multifocal tuberculous spondylitis that has been diagnosed after several percutaneous vertebroplasty. This event supports the theory that surgical or radiological intervention such as a percutaneous vertebroplasty should be considered as an intentional traumatism that can lead to the initiation of a locus minoris resistentiae, probably by reactivating an inactive tuberculous lesion.