RESUMEN
A human biomonitoring study was carried out in the province of Trento, northern Italy, on two groups of women residing in areas with presumably different levels of exposure to polychlorodibenzo-p-dioxins (PCDDs), polychlorodibenzofurans (PCDFs) and polychlorobiphenyls (PCBs). The aim was characterization of the possible impact of a steel plant and an urban environment on the internal doses of these contaminants. The areas investigated were the following: (i) the municipality of Borgo Valsugana, where a steel plant has been operating for the last 30 years, and (ii) the city of Trento. Ten women were enrolled from each area, and breast milk samples were collected from each woman. The amounts of PCDDs, PCDFs and PCBs were analyzed in all samples, and the data obtained were evaluated by descriptive and multivariate statistical approaches. For all samples, the concentrations observed were in the current acceptable concentration range observed in Europe. The descriptive statistics, however, clearly showed that some differences existed between the two groups: the PCDD, PCDF and DL-PCB concentrations were consistently higher in the Trento group of women living in the area surrounding the steel plant. Congener-profile analysis was carried out on both groups, and an appropriate multivariate approach, such as classical factor analysis (CFA), was used to investigate possible differential exposure sources. The application of this approach made it possible to show the quantitative and qualitative differences that characterized the two areas.