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INTRODUCTION: Placement torque and damping capacity may increase when the orthodontic anchor screws make contact with an adjacent root. If this is the case, root contact can be inferred from the placement torque and damping capacity. The purpose of this study was to verify the detectability of root proximity of the screws by placement torque and damping capacity. For this purpose, we investigated the relationship among placement torque, damping capacity, and screw-root proximity. METHODS: The placement torque, damping capacity, and root proximity of 202 screws (diameter, 1.6 mm; length, 8.0 mm) were evaluated in 110 patients (31 male, 79 female; mean age, 21.3 ± 6.9 years). Placement torque was measured using a digital torque tester, damping capacity was measured with a Periotest device (Medizintechnik Gulden, Modautal, Germany), and root contact was judged using cone-beam computed tomography images. RESULTS: The rate of root contact was 18.3%. Placement torque and damping capacity were 7.8 N·cm and 3.8, respectively. The placement torque of screws with root contact was greater than that of screws with no root contact (P <0.05; effect size, 0.44; power, <0.8). Damping capacity of screws with root contact was significantly greater than that of screws with no root contact (P <0.01; effect size, >0.5; power, >0.95). CONCLUSIONS: It was suggested that the damping capacity is related to root contact.
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Aparatos Ortodóncicos , Raíz del Diente , Tomografía Computarizada de Haz Cónico , Femenino , Humanos , Masculino , Métodos de Anclaje en Ortodoncia , Raíz del Diente/diagnóstico por imagen , Torque , Adulto JovenRESUMEN
The authors performed a longitudinal study of the microstructural changes occurring in the mandibular condyle during osteoporosis using the findings obtained from micro-CT. The subjects used in this study were eight Sprague-Dawley rats. Among them, five were administered the immunosuppressant drug FK506 by injection for five weeks, while the other three were administered saline solution in the same manner. Micro-CT images were taken of the bilateral mandibular condyle, hip, and knee joints in all animals on days 1, 8, 15, 22, 29, and 36 following injection. Six indices of morphometric analysis were compared between the two groups. Significant differences were observed in BV/TV, Tb.Th, Tb.N, and Tb.Sp in the mandibular condyle, while trabecular bone density appeared to decrease in the immunosuppressant group on three-dimensional (3D) imaging. And, in comparison with the mandibular condyle and femur, they were similar. These results suggested that osteoporosis affects not only the femur, but also the mandibular condyle.
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Cóndilo Mandibular/patología , Osteoporosis/patología , Animales , Densidad Ósea/fisiología , Médula Ósea/patología , Fémur/patología , Cabeza Femoral/patología , Articulación de la Cadera/patología , Procesamiento de Imagen Asistido por Computador/métodos , Imagenología Tridimensional/métodos , Inmunosupresores/efectos adversos , Articulación de la Rodilla/patología , Estudios Longitudinales , Masculino , Osteoporosis/inducido químicamente , Ratas , Ratas Sprague-Dawley , Tacrolimus/efectos adversos , Microtomografía por Rayos X/métodosRESUMEN
PURPOSE: This study evaluated the contrast-to-noise ratio (CNR), spatial resolution, and subjective quality of dual imaging plates (DIP) intraoral radiography. METHODS: The DIP and conventional single IP (CSIP) methods both used YCR DT-1 imaging plates (Yoshida Co.). The DIP, comprising a front IP (FIP) and back IP (BIP), was constructed. DIP images were synthesized from the FIP and BIP images. An aluminum step phantom was used to measure the CNR. A line pair gauge was used to measure the spatial imaging resolution. A phantom comprising a porcine mandible embedded in acrylic resin was used for subjective evaluation. RESULTS: The CNR of the DIP image was 32% higher than that of the FIP image. The spatial resolution achieved using the FIP, DIP, and CSIP was highly comparable except above 4 line pairs/mm, where that of the CSIP was highest. In subjective evaluation, the noise in the DIP images was significantly lower than in those obtained using the FIP and CSIP. CONCLUSION: The CNR of the DIP was higher than that of the FIP. The decrease in spatial resolution of the DIP was limited. The subjective image quality of the DIP was higher than that of the FIP.
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Relación Señal-Ruido , Animales , Fantasmas de Imagen , Radiografía , PorcinosRESUMEN
The present study used an aluminum phantom to calculate accurate vertical magnification values around the mental foramen on panoramic radiography (PR) and compared corrected PR (Cor-PR) thickness measurements of the aluminum phantom and mandibular cortical width (MCW) of the human head with cone-beam computed tomography (CBCT) measurements at two fields of view (FOVs). The calculated vertical magnification value for PR around the mental foramen was 1.37. Measurements of the aluminum phantom significantly differed between Cor-PR and CBCT with an FOV of 100 mm and between CBCT with FOVs of 40 and 100 mm; however, MCW measurements did not significantly differ among the three methods. There was a very strong correlation between Cor-PR and CBCT with an FOV of 40 mm and between CBCT with FOVs of 40 mm and 100 mm, and intraobserver and interobserver agreement was good-to-excellent for all methods. These results suggest that Cor-PR and CBCT with small and large FOVs are acceptable for measuring MCW.
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Tomografía Computarizada de Haz Cónico , Mandíbula , Humanos , Foramen Mental , Radiografía Panorámica , Reproducibilidad de los ResultadosRESUMEN
The outbreak of novel coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has spread worldwide. Nasopharyngeal swabs are widely used in polymerase chain reaction (PCR) test to detect SARS-CoV-2. However, the collection of nasopharyngeal swabs has a series of drawbacks concerning exposure of healthcare staff, difficulty in collection, and discomfort of patients. Therefore, an alternative noninvasive sample for diagnostic of emerging viral diseases is required. The usefulness of saliva screening tests is compared to conventional swab tests in this report. The results suggest that saliva could be a reliable sample for detecting SARS-CoV-2.
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Coronavirus Relacionado al Síndrome Respiratorio Agudo Severo , Betacoronavirus , COVID-19 , Técnicas de Laboratorio Clínico , Infecciones por Coronavirus , Humanos , Pandemias , Neumonía Viral , Reacción en Cadena de la Polimerasa , SARS-CoV-2 , SalivaRESUMEN
This study was performed to develop a new rat model of reduced masticatory activity in order to assess the effect of this reduction on the morphology of the temporomandibular joint (TMJ) over time. Female rats were used, and ovariectomy was performed to simulate aged/postmenopausal status. Twenty-four SD rats aged 6 weeks were divided into four groups: ovariectomy/sham procedure (Ov/S); ovariectomy/reduced masticatory activity (Ov/RMA); non-Ov/S (NO/S); and non-Ov/RMA (NO/RMA). The RMA procedure involved grinding down the edges of the upper and mandibular incisors by about 3 mm and supplying the rats with a powdered diet. The bilateral TMJ was examined by micro-computed tomography at 0, 1, 2, 4, 6, and 8 weeks after the start of RMA. Condylar width was greater in the NO/S group than in the Ov/S group after the 2nd week, showing that ovariectomy reduced the width of the condyle. After the 2nd week, significant differences in condylar width were apparent between the NO/S and NO/RMA groups, and between the Ov/S and Ov/RMA groups. This RMA procedure appeared to provide a good model of reduced masticatory activity. The present findings in female rats suggest that reduction of appropriate mastication activity in the growth period results in poor growth of the mandibular condyle and immediately induces atrophy of the mandibular condyle under conditions simulating aged/postmenopausal status.
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Cóndilo Mandibular , Masticación , Animales , Atrofia , Femenino , Modelos Animales , Ratas , Ratas Sprague-Dawley , Microtomografía por Rayos XRESUMEN
PURPOSE: Circadian rhythm is associated with the pathogenesis of systemic disease and bone mineral metabolism. This study aimed to radiographically evaluate morphological characteristics of the interalveolar septum in circadian rhythm deficient animals. METHODS: Heads of 10 brain and muscle arnt-like protein-1 (BMAL1)-knockout (KO) mice and 10 wild-type mice sacrificed at 36 weeks were imaged using micro-computed tomography. The mean depth from the cementoenamel junction to the alveolar ridge (virtual bone sounding: VBS) of the interalveolar septum between the first and second molars, and the bone mineral density (BMD) of the interalveolar septum and the mandibular inferior cortex region were calculated. Tooth diameter was also measured. RESULTS: The VBS of the interalveolar septum in the BMAL1-KO mice was significantly deeper than that in wild-type mice. The BMD in the BMAL1-KO mice was significantly lower than in the wild-type mice in both regions. No significant difference was observed in tooth diameter between BMAL1-KO and wild-type mice. CONCLUSION: These results suggest that low BMD in the interalveolar septum accelerates bone resorption in the interalveolar septum in BMAL1-KO mice.
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Factores de Transcripción ARNTL , Mandíbula , Factores de Transcripción ARNTL/genética , Animales , Técnicas de Inactivación de Genes , Mandíbula/diagnóstico por imagen , Ratones , Ratones Endogámicos C57BL , Ratones Noqueados , Microtomografía por Rayos XRESUMEN
The lack of information on oral health in Laos makes it difficult to estimate the need and methods for preventing oral disease. This study identified problems concerning the oral health of Lao children. The study subjects were 59 school children who lived in Pakkading District. Dental caries, gingivitis malocclusions, temporomandibular joint (TMJ) disorders, dental plaque, and calculus were examined. We observed an average of 1.6 decayed, missing, and filled teeth (DMFT) and 4.1 decayed and filled deciduous teeth (dft) per child. 25.4% had gingivitis scores from 16 to 20 on the papillary, marginal, and attached (PMA) index; 29.6% had one or more occlusal abnormality; and 0% had signs of TMJ disorders. 93.5% of the children had at least one buccal or lingual tooth surface with plaque covering more than two thirds of the surface; 32.6% had dental calculus. Oral health promotion programs for children should prioritise prevention and treatment of caries. It is likely that the high rate of gingivitis in Lao children is due mainly to unsuccessful plaque control in daily life. In addition to descriptive epidemiological studies of dental diseases in other areas, the influence of sociological and behavioural factors on oral health should be analyzed epidemiologically to promote child health.
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Enfermedades de la Boca/epidemiología , Salud Rural/estadística & datos numéricos , Trastornos de la Articulación Temporomandibular/epidemiología , Enfermedades Dentales/epidemiología , Niño , Índice CPO , Cálculos Dentales/epidemiología , Caries Dental/epidemiología , Placa Dental/epidemiología , Restauración Dental Permanente/estadística & datos numéricos , Femenino , Gingivitis/epidemiología , Humanos , Laos/epidemiología , Masculino , Maloclusión/epidemiología , Salud Bucal , Índice de Higiene Oral , Prevalencia , Pérdida de Diente/epidemiología , Diente Primario/patologíaRESUMEN
We compared the diagnostic reliability of 3.0-T magnetic resonance imaging (MRI) for detection of osseous abnormalities of the temporomandibular joint (TMJ) with that of the gold standard, cone-beam computed tomography (CBCT). Fifty-six TMJs were imaged with CBCT and MRI, and images of condyles and fossae were independently assessed for the presence of osseous abnormalities. The accuracy, sensitivity, and specificity of 3.0-T MRI were 0.88, 1.0, and 0.73, respectively, in condyle evaluation and 0.91, 0.75, and 0.95 in fossa evaluation. The McNemar test showed no significant difference (P > 0.05) between MRI and CBCT in the evaluation of osseous abnormalities in condyles and fossae. The present results indicate that 3.0-T MRI is equal to CBCT in the diagnostic evaluation of osseous abnormalities of the mandibular condyle.
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Tomografía Computarizada de Haz Cónico/métodos , Imagen por Resonancia Magnética/métodos , Articulación Temporomandibular/anomalías , Adulto , Femenino , Humanos , Masculino , Persona de Mediana Edad , Sensibilidad y EspecificidadRESUMEN
Brain and muscle Arnt-like protein-1 (BMAL1) knockout mice exhibit accelerated aging, abnormal glucose metabolism, and impaired adipocyte differentiation, among other phenotypes, which are effects associated with the BMAL1 gene. No study has investigated temporal changes in the deformation of the mandibular condyle and the presence of calcification in areas surrounding the mandibular condyle. In a study of 12 C57/BL strain mice under inhalation anesthesia, we collected images of the mandibular condyle at 6 weeks after birth and then every 5 weeks from 10 to 25 weeks after birth. At 25 weeks, deformation of the mandibular condyle was seen in 8 of 12 joints in BMAL1 knockout mice and in 2 of 12 joints in wild-type mice. At 20 and 25 weeks, deformation in areas surrounding the mandibular condyle, which are known to undergo calcification, was seen in 2 of 12 joints in BMAL1 knockout mice and in 0 of 12 joints in wild-type mice. BMAL1 knockout mice exhibited premature aging of the mandibular condyle, which suggests that circadian rhythms affect mandibular condyle morphology.
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Factores de Transcripción ARNTL , Cóndilo Mandibular/diagnóstico por imagen , Cóndilo Mandibular/fisiopatología , Microtomografía por Rayos X , Animales , Calcinosis/diagnóstico por imagen , Calcinosis/fisiopatología , Relojes Circadianos , Femenino , Masculino , Ratones , Ratones Endogámicos C57BL , Ratones Noqueados , Fenotipo , Factores de TiempoRESUMEN
Dental cone-beam computed tomography (CBCT) received regulatory approval in Japan in 2000 and has been widely used since being approved for coverage by the National Health Insurance system in 2012. This imaging technique allows dental practitioners to observe and diagnose lesions in the dental hard tissue in three dimensions (3D). When performing routine radiography, the examination must be justified, and optimal protection should be provided according to the ALARA (as low as reasonably achievable) principles laid down by the International Commission on Radiological Protection. Dental CBCT should be performed in such a way that the radiation exposure is minimized and the benefits to the patient are maximized. There is a growing demand for widespread access to cutting-edge health care through Japan's universal health insurance system. However, at the same time, people want our limited human, material, and financial resources to be used efficiently while providing safe health care at the least possible cost to society. Japan's aging population is expected to reach a peak in 2025, when most of the baby boomer generation will be aged 75 years or older. Comprehensive health care networks are needed to overcome these challenges. Against this background, we hope that this text will contribute to the nation's oral health by encouraging efficient use of dental CBCT.
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Tomografía Computarizada de Haz Cónico/normas , Guías de Práctica Clínica como Asunto , Radiografía Dental/normas , Humanos , JapónRESUMEN
Considerable advances have been made in dental and orthodontic diagnosis resulting from the development of a device known as a limited cone beam dental compact-CT (3DX). This report documents the diagnostic procedures and treatment performed on an eight year old female patient who presented with clinical signs and symptoms of a temporomandibular disorder (TMD). Evaluation of a bony abnormality of the temporomandibular joint (TMJ) using the limited cone-beam CT (3DX) proved to be of considerable value. A three-dimensional image of the right TMJ showed erosion and flattening of the condyle. Following treatment, there was marked alleviation of the clinical symptoms while considerable improvement of the bony abnormalities was clearly evident on a three-dimensional image.
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Imagenología Tridimensional/métodos , Trastornos de la Articulación Temporomandibular/diagnóstico por imagen , Tomografía Computarizada por Rayos X/métodos , Bruxismo/complicaciones , Niño , Oclusión Dental Traumática/complicaciones , Femenino , Humanos , Cóndilo Mandibular/diagnóstico por imagen , Enfermedades Mandibulares/diagnóstico por imagen , Hábito de Comerse las Uñas , Ferulas OclusalesRESUMEN
The occurrence of ameloblastic fibro-odontoma (AFO) in the oral region is unusual and accounts for 1-3% of all odontogenic tumors. AFO presents mixed radiopaque patterns within the lesion with diverse findings; therefore, it is important to compare this tumor with other odontogenic tumors that radiographically present with calcified bodies. Herein, we observed the calcification patterns within the lesion in seven AFO cases (five males, two females; mean age, 8.3 years; age range, 4-13 years). Periapical and panoramic radiographs were obtained from all seven cases. Five cases underwent conventional computed tomography (CT) scanning, and one underwent cone beam CT. Classification of the calcifications primarily involved the following two characteristics on the X-rays: appearance and location of the lesions. All seven cases were located in the molar regions of the mandible in association with impacted teeth. The calcification patterns of these AFOs were mixed or inhomogeneous within the lesion with various findings, including complex odontoma-like calcifications. However, the patterns differed between panoramic radiography and CT in some cases. The radiolucent lesions in AFO demonstrated varying calcification patterns and were associated with impacted teeth on the CT images.(J Oral Sci 58, 533-537, 2016).
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Calcinosis/diagnóstico por imagen , Odontoma/diagnóstico por imagen , Adolescente , Niño , Preescolar , Femenino , Humanos , Masculino , Estudios RetrospectivosRESUMEN
PURPOSE: This study was performed to determine the accuracy of measurements of bone mineral density (BMD) and cortical bone thickness (CBT) at miniscrew implantation sites in small animals and to verify the usefulness of in vivo microcomputed tomography (micro-CT). MATERIALS AND METHODS: Rat femurs were scanned before and after placing miniscrews using in vivo micro-CT. The images were superimposed using a subtraction method with bone volume measurement software. At each screw site, the total BMD was calculated as the average BMD of a cylinder 1.6 mm in diameter and 2.0 mm in depth, while the cortical BMD was the average BMD of a cylinder 1.6 mm in diameter and 1.0 mm in depth. CBT was measured three times on transaxial images of the rat femurs, and the average value was used. All miniscrews were placed using the maximum torque, verified with a digital torque tester. To verify the usefulness and accuracy of in vivo micro-CT, CBT on micro-CT images was compared with that measured on histologic sections. RESULTS: Significant correlations were observed between placement torque and cortical BMD (R = 0.572), total BMD (R = 0.732), and CBT (R = 0.788). There was a significant correlation between CBT measured via field-emission scanning electron microscopy images and CBT measured with in vivo micro-CT (R = 0.974). CONCLUSIONS: The BMD over a narrow range can be measured accurately in small animals with high reproducibility of the trabecular structure using a combination of high-resolution in vivo micro-CT and image superimposition using a three-dimensional subtraction method.
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Densidad Ósea/fisiología , Tornillos Óseos , Métodos de Anclaje en Ortodoncia/instrumentación , Microtomografía por Rayos X , Animales , Fémur/diagnóstico por imagen , Fémur/cirugía , Microscopía Electrónica de Rastreo , Modelos Animales , Métodos de Anclaje en Ortodoncia/normas , Ratas , Reproducibilidad de los ResultadosRESUMEN
We measured the gonial angle (GA) on panoramic radiography (PR) and analyzed the correlation between the GA on PR and lateral cephalometric radiography (LCR). In total, 49 PR films and LCR films from dentate young adults were evaluated. Orthodontists plotted four points (articulare, menton, posterior gonion, and lower gonion) on the PR and carefully traced them. Using a protractor, two radiologists measured the GA on LCR images. A simultaneous experimental study of two dry skulls was performed to compare the GA on LCR and PR. The GA was slightly smaller on the PR of the dry mandible than on the LCR and tended to decrease continuously with magnitude toward the Frankfort horizontal plane. The mean GA was 115.1 ± 5.2° on PR and 122.2 ± 6.4° on the LCR. The values were highly correlated (Pearson product-moment correlation coefficient, 0.801). The GA on PR was nonsignificantly smaller than that measured on LCR. The difference may be due to head position, the inclination angle of the mandibular body, and/or the direction of the incident X-ray beam.
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Cefalometría/métodos , Humanos , Radiografía Panorámica , Cráneo/diagnóstico por imagenRESUMEN
We describe a rare case of osteochondroma of the coronoid process of mandible accompanied by severe trismus in a 14-year-old Japanese boy. The patient had initially been diagnosed as having internal derangement of the temporomandibular joint (TMJ), and conservative treatment had failed to improve the symptoms. Despite extremely limited TMJ movement, panoramic radiography revealed no abnormality, but magnetic resonance imaging suggested internal derangement of the left TMJ. Five months later, the trismus worsened and computed tomography revealed a bone-like mass confluent with the coronoid process, which was finally diagnosed as osteochondroma. The patient then underwent intra-oral coronoidectomy.
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Neoplasias Mandibulares/diagnóstico , Osteocondroma/diagnóstico , Adolescente , Humanos , Imagen por Resonancia Magnética , Masculino , Neoplasias Mandibulares/complicaciones , Neoplasias Mandibulares/diagnóstico por imagen , Neoplasias Mandibulares/patología , Osteocondroma/complicaciones , Osteocondroma/diagnóstico por imagen , Osteocondroma/patología , Radiografía Panorámica , Tomografía Computarizada por Rayos X , Trismo/complicacionesRESUMEN
OBJECTIVE: To evaluate whether morphological discrepancy between the mandibular condyle and fossa of the temporomandibular joint (TMJ) is related to disk displacement on magnetic resonance imaging (MRI). STUDY DESIGN: This study included 61 patients with unilateral internal derangement based on both MRI and clinical examination. Coronal morphologies of the condyle and fossa were divided into four groups based on Öberg's classification. According to the coronal morphology of the condyle and fossa, all joints were dichotomized into either harmonized group or a discrepancy group (e.g., angled condyle and concave fossa). The incidence of discrepancy and the relationship of the discrepancy to other findings on MRI were statistically evaluated. RESULTS: The discrepancy had a significantly higher incidence on the affected side. The discrepancy correlated with incidence of disk deformity on the affected side. CONCLUSION: Morphological discrepancy between the condyle and fossa is related to development of anterior disk displacement in the TMJ.
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Imagen por Resonancia Magnética , Cóndilo Mandibular/patología , Disco de la Articulación Temporomandibular/patología , Trastornos de la Articulación Temporomandibular/patología , Adulto , Femenino , Humanos , Masculino , Trastornos de la Articulación Temporomandibular/etiologíaRESUMEN
This study aimed to show the effects of metal artifacts on the in vivo micro-CT of mini-implants by measuring bone volume. We drilled a hole in the cortical bone of a rat tibia and embedded a titanium orthodontic mini-implant (diameter, 1.5 mm) in the hole. Twelve individually weighed hydroxyapatite grains (HA grains) were placed around the implant either by one dentist (method 1) or separately by 12 dentists (method 2). In vivo micro-CT was used to scan the model after placement of each grain to measure increases and decreases in bone volume voxel number. The subtracted bone voxel volume increased with HA weight in both methods. Simple linear regression analysis showed a significant correlation between weight and volume in both methods (method 1: regression coefficient: 516.502, P < 0.05; method 2: regression coefficient: 4837.432, P < 0.05). Metal artifacts did not appear to influence measurements of bone volume, although further studies are required to determine the effect of thicker implants.
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Artefactos , Densidad Ósea , Implantes Dentales , Métodos de Anclaje en Ortodoncia/instrumentación , Microtomografía por Rayos X , Animales , Durapatita , Implantes Experimentales , Modelos Lineales , Metales , Ratas , Tibia/diagnóstico por imagen , Tibia/cirugía , TitanioRESUMEN
OBJECTIVE: The objective of this study was to compare an image-guided puncture technique (IGPT) with conventional puncture technique (CPT) with respect to accuracy of needle entry, maximal mouth opening, and pain in pumping manipulation treatment of internal derangement of the temporomandibular joint (TMJ). STUDY DESIGN: The subjects comprised 178 patients with internal derangement of the TMJ with closed lock. Treatment was provided using CPT in 102 cases and IGPT in 76 cases. Three variables, number of repunctures, maximal mouth opening distance, and pain threshold according to a visual analogue scale, were measured and compared between IGPT and CPT groups. RESULTS: Access to the superior joint cavity was achieved without correcting the puncture point in 97% of patients who underwent IGPT and 82% of patients in the CPT group. Significant differences were seen in 1-week maximal mouth opening and pain threshold between IGPT and CPT groups (P < .05 each) and resetting of the puncture point was significantly less frequent using IGPT compared with CPT (P < .05). CONCLUSIONS: IGPT is effective for pain mitigation and improves mouth opening during the early postoperative period after pumping manipulation treatment.
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Punciones/métodos , Radiografía Intervencional , Trastornos de la Articulación Temporomandibular/cirugía , Articulación Temporomandibular/cirugía , Adolescente , Adulto , Artrografía , Tomografía Computarizada de Haz Cónico , Femenino , Marcadores Fiduciales , Humanos , Masculino , Persona de Mediana Edad , Dimensión del Dolor , Palpación , Radiografía Intervencional/métodos , Rango del Movimiento Articular , Estadísticas no Paramétricas , Articulación Temporomandibular/diagnóstico por imagen , Trastornos de la Articulación Temporomandibular/diagnóstico por imagen , Adulto JovenRESUMEN
Panoramic radiography and cone-beam computed tomography (CT) were used to analyze asymptomatic radiopaque lesions in the jaw bones and determine the diagnostic relevance of the lesions based on their relationships to teeth and site of origin. One hundred radiopaque lesions detected between 1998 and 2002 were examined by both panoramic radiography and cone-beam CT. On the basis of panoramic radiographs, the region was classified as periapical, body, or edentulous, and the site was classified as molar or premolar. Follow-up data from medical records were available for only 36 of these cases. The study protocol for simultaneous use of cone-beam CT was approved by the ethics review board of our institution. A large majority of radiopaque lesions were observed in premolar and molar sites of the mandible; 60% of lesions were periapical, 24% were in the body, and 16% were in the edentulous region. An interesting type of radiopaque lesion, which we named a pearl shell structure (PSS), was observed on cone-beam CT in 34 of the 100 lesions. The PSS is a distinctive structure, and this finding on cone-beam CT likely represents the start of bone formation before bone sclerosis.