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1.
J Perinat Med ; 49(4): 520-525, 2021 May 26.
Artículo en Inglés | MEDLINE | ID: mdl-33470963

RESUMEN

OBJECTIVES: To examine whether audio-voice guidance application improves adherence to resuscitation sequence and recommended time frames during neonatal resuscitation. METHODS: A prospective, randomized, pilot study examining the use of an audio-voice application for guiding resuscitation on newborn mannequins, based on the Neonatal Resuscitation Program (NRP) algorithm. Two different scenarios, with and without voice guidance, were presented to 20 medical personnel (2 midwives, 8 nurses, and 10 physicians) in random order, and their performance videotaped. RESULTS: Audio-voice guided resuscitation compared with non-guided resuscitation, resulted in significantly better compliance with NRP order sequence (p<0.01), correct use of oxygen supplementation (p<0.01) and performance of MR SOPA (Mask, reposition, suction, open mouth, pressure, airway) (p<0.01), and shortened the time to "positive pressure ventilation" (p<0.01). CONCLUSIONS: In this pilot study, audio-voice guidance application for newborn resuscitation simulation on mannequins, based on the NRP algorithm, improved adherence and performance of NRP guidelines.


Asunto(s)
Competencia Clínica , Resucitación , Entrenamiento Simulado/métodos , Análisis y Desempeño de Tareas , Materiales de Enseñanza/normas , Algoritmos , Duración de la Terapia , Adhesión a Directriz , Humanos , Recién Nacido , Maniquíes , Aplicaciones de la Informática Médica , Proyectos Piloto , Resucitación/métodos , Resucitación/normas
2.
Science ; 383(6688): eadj9223, 2024 Mar 15.
Artículo en Inglés | MEDLINE | ID: mdl-38484069

RESUMEN

Humans, like all mammals, depend on the gut microbiome for digestion of cellulose, the main component of plant fiber. However, evidence for cellulose fermentation in the human gut is scarce. We have identified ruminococcal species in the gut microbiota of human populations that assemble functional multienzymatic cellulosome structures capable of degrading plant cell wall polysaccharides. One of these species, which is strongly associated with humans, likely originated in the ruminant gut and was subsequently transferred to the human gut, potentially during domestication where it underwent diversification and diet-related adaptation through the acquisition of genes from other gut microbes. Collectively, these species are abundant and widespread among ancient humans, hunter-gatherers, and rural populations but are rare in populations from industrialized societies thus indicating potential disappearance in response to the westernized lifestyle.


Asunto(s)
Celulosa , Fibras de la Dieta , Microbioma Gastrointestinal , Ruminococcus , Humanos , Celulosa/metabolismo , Microbioma Gastrointestinal/genética , Microbioma Gastrointestinal/fisiología , Ruminococcus/clasificación , Ruminococcus/enzimología , Ruminococcus/genética , Fibras de la Dieta/metabolismo , Filogenia , Desarrollo Industrial
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