Microfibrous borate bioactive glass dressing sequesters bone-bound bisphosphonate in the presence of simulated body fluid.

Ion exchange occurs between borate bioactive glass and simulated body fluid. Borate bioactive glass dressings may be used for managing bisphosphonate-related osteonecrosis of the jaw through the formation of a complex incorporating leached calcium and borate ions and sequestered bone-bound bisphosphonates.