Influence of Platelet-Poor Plasma on Angiogenesis and Maintenance of Volume in Autogenous Bone Grafts.

PURPOSE: The aim of this study was to evaluate the effect of different storage media on angiogenesis and maintaining autogenous bone graft volume in rabbits. MATERIAL AND METHODS: Two grafts were removed bilaterally from the calvaria of 18 rabbits. One graft was removed and immediately fixed in the right mandibular angle (control group). The other graft was stored for 30 minutes in 1 of the following storage media (n = 6): saline solution (saline group), air exposure (dry group), or platelet-poor plasma (PPP group) and then retained by a screw in the right mandibular angle in the same animal. Four weeks later the animals were euthanized, and the grafted areas were harvested, fixed in 10% phosphate buffered formaldehyde solution, and embedded in paraffin. The 5-µm semi-serial sections were stained in hematoxylin and eosin and Mallory trichrome. RESULTS: Histologic analysis of all groups showed the bone graft was vascularized and well incorporated into the recipient site. The number of blood vessels decreased in the saline and dry groups compared with the control group (P < .03); in contrast, the number of blood vessels increased in the PPP group (P < .05). There were fewer osteoclasts in the saline group compared with the control group (P < .05). Furthermore, the saline group showed larger numbers of blood vessels than the dry group (P < .01). The PPP group showed larger bone graft volumes compared with the dry and saline groups (P < .01). In addition, the saline group showed larger bone graft volumes than the dry group (P < .01). CONCLUSIONS: PPP improved angiogenesis, maintained the volume of the autogenous bone graft, and was a better storage medium during the trans-surgical period than the dry and saline media.

The Effect of Local Delivery Doxycycline and Alendronate on Bone Repair.

The aim of the present study was to investigate the local effect of 10% doxycycline and 1% alendronate combined with poly(lactic-co-glycolic acid) (PLGA) on bone repair. Thirty rats were divided into three groups, as follows: control group (CG), drug group (DG), and vehicle-PLGA group (VG). Bone defect was created in the right femur and filled with the following: blood clot (CG); PLGA gel, 10% doxycycline and 1% alendronate (DG); or vehicle-PLGA (VG). The animals were euthanized 7 or 15 days after surgery. Bone density, bone matrix and number of osteoclasts were quantified. At 7 days, the findings showed increased density in DG (177.75 ± 76.5) compared with CG (80.37 ± 27.4), but no difference compared with VG (147.1 ± 41.5); no statistical difference in bone neoformation CG (25.6 ± 4.8), VG (27.8 ± 4), and DG (18.9 ± 7.8); and decrease osteoclasts in DG (4.6 ± 1.9) compared with CG (26.7 ± 7.4) and VG (17.3 ± 2.7). At 15 days, DG (405.1 ± 63.1) presented higher density than CG (213.2 ± 60.9) and VG (283.4 ± 85.8); there was a significant increase in percentage of bone neoformation in DG (31.5 ± 4.2) compared with CG (23 ± 4), but no difference compared with VG (25.1 ± 2.9). There was a decreased number of osteoclasts in DG (20.7 ± 4.7) and VG (29.5 ± 5.4) compared with CG (40 ± 9.4). The results suggest that the association of 10% doxycycline and 1% alendronate with PLGA-accelerated bone repair.

Treatment of temporomandibular joint ankylosis by posterior border of mandibular ramus osteotomy.

Temporomandibular joint (TMJ) ankylosis (TMJA) is an anatomic and functional alteration of the TMJ surfaces, caused by the fusion of these surfaces by either bone or fibrous tissue. Several techniques are used for the treatment of TMJA. The following case report describes a 5-year-old boy who was diagnosed with TMJA. The treatment of choice is reconstruction of the condyle by sliding the posterior border of the mandibular ramus. Temporomandibular joint ankylosis treatment with vertical ramus osteotomy and mandibular posterior border repositioning offers minimizing the reduction in height or shortening of the mandibular posterior border. The postoperative period requires a multidisciplinary approach with an aggressive physiotherapy.

Saliva versus peri-implant inflammation: quantification of IL-1ß in partially and totally edentulous patients.

The aim of this study was to investigate the potential use of salivary IL1ß in early-stage diagnostics of peri-implant inflammation in partially and totally edentulous patients rehabilitated with dental implants. Patients were classified according to peri-implant probing depth and bleeding upon probing in groups of healthy individuals or in groups of individuals with peri-implant inflammation. Data on plaque index, clinical attachment loss, suppuration, and mobility were also assessed. Saliva was collected without stimulation, and the levels of IL-1ß were determined by ELISA. Healthy groups demonstrated significantly lower levels of IL-1ß compared with the inflammation groups. No difference in IL-1ß levels was observed between partially edentulous or totally edentulous patients. Salivary IL-1ß may be useful for the diagnosis and monitoring of early peri-implant inflammation, particularly in edentulous patients.

Effect of different storage media on the regenerative potential of autogenous bone grafts: a histomorphometrical analysis in rabbits.

The success of autogenous bone graft is related to the graft cell viability. In bone-grafting procedures, harvested grafts are often maintained in extraoral media while the recipient site is prepared. The aim of this study was to evaluate in vivo the effect of storage media over autogenous bone grafts during the transsurgical time. Two grafts were removed bilaterally from the calvaria of 18 rabbits. One graft was immediately fixed in the mandibular angle (control group), and the other was maintained in air exposure (dry group), 0.9% NaCl solution (saline group), or platelet-poor plasma (PPP group) during 30 minutes and stabilized in the symmetrical location of control grafts. After 28 days, the animals were euthanized and the bone fragments were removed, demineralized, and embedded in paraffin. Histological evaluation was performed under light microscope. Empty lacunae and bone graft area quantification were carried out for the sections. The histomorphometrical analysis revealed reduction of the graft area and increase of empty lacunae in the dry group when compared with control. No significant differences were found in the number of empty lacunae or bone graft area between the saline group and its control and also between the PPP group and its control. The dry group showed more empty lacunae and less graft area than the saline and PPP groups. In accordance with the results, PPP and physiologic solution demonstrated osteocyte preservation and bone graft area maintenance, being satisfactory storage media for autogenous bone grafts during the transsurgical period.

Bovine anorganic bone graft associated with platelet-rich plasma: histologic analysis in rabbit calvaria.

Autogenous bone tissue has regeneration potential; however, this capacity may not be sufficient in larger bone defects. The aim of this study is to histologically evaluate anorganic bovine bone grafts (GenOx Inorg) with or without platelet-rich plasma (PRP). Two bone lesions were created in calvaria of 12 rabbits. The 24 surgical lesions were separated into 3 groups: coagulous, anorganic, and anorganic with PRP. At the 4-week time point, the animals were euthanized and the grafted area removed, fixed in formalin 10% with phosphate buffered saline, 0.1 M, and embedded in paraffin. The histologic parameters analyzed were new bone filling the defect area, presence of giant cells and particles of the graft, and new bone formation associated with the particles. In the coagulous group, defects were filled with fibrous tissue that attached the periosteum and little bone neoformation in the periphery. In anorganic groups with or without PRP, little new bone formation in the periphery of the defect was observed; however, in the center of some defects there was new bone. Moderate presence of giant cells and little new bone formation was associated with the innumerous graft particles. Histologic results revealed no statistically significant differences among the defects new bone fill between the studied groups (P = .64). There was no significant difference in the number of giant cells (P = .60), graft particles (P = .46), and new bone formation around graft particles (P = .26), whether PRP was added or not. Anorganic bone, isolated or mixed with PRP, was biocompatible and osteoconductive, while maintaining bone volume.

Retrospective study of bone grafting procedures before implant placement.

AIM: The aim of this retrospective study was to evaluate morbidity and possible complications in augmentation procedures before implant placement. METHODS: Records from 93 consecutive patients with indication for autogenous bone grafting before implant placement, treated at Department of Oral and Maxillofacial Surgery and Implantology of Uberlândia Federal University, in a 7-year period (July 2000 until July 2007), were reviewed. The need for bone grafting was defined by the impossibility of installing implants of adequate length or diameter to fulfill prosthetic requirements or for aesthetic reasons. RESULTS: A total of 136 bone grafting procedures were performed. The mandibular external oblique line and ascending ramus were the most frequently used donor areas (59.64%) and block grafts (67.64%) were the most frequently used type of graft, frequently from the mandibular external oblique line/ascending ramus (52.18%). Platelet-rich plasma was used in 20.1% of all procedures, usually associated with particulate bone grafts. Maxillary procedures represented the majority of surgeries (75%), but with fewer complications compared with the mandible. Sinus mucosa perforation was the most frequent complication in maxillary procedures, whereas graft exposure was the most common complication in mandible. CONCLUSIONS: Alveolar reconstruction using autogenous bone followed by implant placement is a reliable treatment for patients with insufficient bone. Complications and morbidity were frequently observed. However, in only 6.6% of all procedures, the final rehabilitation with dental implants was not possible.

Implant-supported Dental Prosthesis and Orthognathic Surgery for Rehabilitation of Patients with Obstructive Sleep Apnea / Prótese Dentária Implanto-suportada e Cirurgia Ortognática para Reabilitação de Pacientes com Apneia Obstrutiva do Sono

Among the treatment options for Obstructive Sleep Apnea (OSA) we have surgery to correct dentofacial deformities. OSA patients are routinely and predictably submitted to surgical treatment for dentofacial deformities. Frequently, orthognathic surgery and osseointegrated implants may be necessary to enable fixed rehabilitation. Patients submitted to orthognathic surgery have a transient decrease in blood supply after maxillary and mandibular osteotomy procedures, which can impair the results in these cases. This case report aimed to present and discuss the conflicting situation of an OSA patient in need of orthognathic surgery and dental implants. The treatment consisted of: (1) extraction of all teeth; (2) complete rehabilitation of the upper and lower jaw with dental implants and prosthesis without compensation; (3) bimaxillary orthognathic surgery to re-establish the maxillomandibular relationship and increase the upper airway volume. This rehabilitation sequence was a safe alternative for a case of Class II OSA, and rapidly achieved a final restoration with enhanced esthetics, functionality, biomechanics, maintenance of oral hygiene, and patient satisfaction (AU)

Entre as opções de tratamento da Apneia Obstrutiva do Sono (AOS) temos a cirurgia para correção das deformidades dentofaciais. Freqüentemente, a combinação de cirurgia ortognática e implantes osseointegráveis pode ser necessária para permitir a reabilitação dental. Pacientes submetidos à cirurgia ortognática apresentam diminuição transitória do suprimento sanguíneo após procedimentos de osteotomia maxilar e mandibular, o que pode prejudicar os resultados nestes casos. Este relato de caso teve como objetivo apresentar e discutir a situação de um paciente com AOS que necessita de cirurgia ortognática e implantes dentários. O tratamento consistiu em: (1) extração de todos os dentes; (2) reabilitação completa da mandíbula superior e inferior com implantes dentários e próteses sem compensação; (3) cirurgia ortognática bimaxilar para restabelecer a relação maxilomandibular e aumentar o volume das vias aéreas superiores. Essa sequência de reabilitação foi uma alternativa segura para um caso de AOS Classe II, e rapidamente alcançou uma reabilitação com estética, funcionalidade, biomecânica aprimorada, manutenção da higiene oral e satisfação do paciente

Implant-supported Dental Prosthesis and Orthognathic Surgery for Rehabilitation of Patients with Obstructive Sleep Apnea / Prótese Dentária Implanto-suportada e Cirurgia Ortognática para Reabilitação de Pacientes com Apneia Obstrutiva do Sono

ABSTRACT: Among the treatment options for Obstructive Sleep Apnea (OSA) we have surgery to correct dentofacial deformities. OSA patients are routinely and predictably submitted to surgical treatment for dentofacial deformities. Frequently, orthognathic surgery and osseointegrated implants may be necessary to enable fixed rehabilitation. Patients submitted to orthognathic surgery have a transient decrease in blood supply after maxillary and mandibular osteotomy procedures, which can impair the results in these cases. This case report aimed to present and discuss the conflicting situation of an OSA patient in need of orthognathic surgery and dental implants. The treatment consisted of: (1) extraction of all teeth; (2) complete rehabilitation of the upper and lower jaw with dental implants and prosthesis without compensation; (3) bimaxillary orthognathic surgery to re-establish the maxillomandibular relationship and increase the upper airway volume. This rehabilitation sequence was a safe alternative for a case of Class II OSA, and rapidly achieved a final restoration with enhanced esthetics, functionality, biomechanics, maintenance of oral hygiene, and patient satisfaction. (AU)

RESUMO: Entre as opções de tratamento da Apneia Obstrutiva do Sono (AOS) temos a cirurgia para correção das deformidades dentofaciais. Freqüentemente, a combinação de cirurgia ortognática e implantes osseointegráveis pode ser necessária para permitir a reabilitação dental. Pacientes submetidos à cirurgia ortognática apresentam diminuição transitória do suprimento sanguíneo após procedimentos de osteotomia maxilar e mandibular, o que pode prejudicar os resultados nestes casos. Este relato de caso teve como objetivo apresentar e discutir a situação de um paciente com AOS que necessita de cirurgia ortognática e implantes dentários. O tratamento consistiu em: (1) extração de todos os dentes; (2) reabilitação completa da mandíbula superior e inferior com implantes dentários e próteses sem compensação; (3) cirurgia ortognática bimaxilar para restabelecer a relação maxilomandibular e aumentar o volume das vias aéreas superiores. Essa sequência de reabilitação foi uma alternativa segura para um caso de AOS Classe II, e rapidamente alcançou uma reabilitação com estética, funcionalidade, biomecânica aprimorada, manutenção da higiene oral e satisfação do paciente. (AU)

Terceiro Molar Ectópico em Incisura Mandibular / Ectopic Third Molar in the Mandibular Notch

Dentes ectópicos são frequentemente encontrados, entretanto, terceiros molares inferiores ectópicos são inco-muns, com etiologia obscura e pouco descritos na literatura pertinente. Sua localização já foi relatada nas regiões condilar, subcondilar, incisura mandibular, ângulo e borda inferior da mandíbula. Devido à importância do plane-jamento terapêutico, manejo adequado e variedade das manifestações clínicas desta condição, este trabalho teve como objetivo relatar um caso clínico de terceiro molar inferior ectópico na região de incisura mandibular, com radiolucência aumentada ao redor da coroa, em um paciente do gênero masculino, de 28 anos e sem sintomato-logia. Acompanhamento radiográfico pode ser indicado, no entanto, em pacientes sintomáticos ou com alterações patológicas associadas, a extração deve ser considerada. Diante disso, o tratamento de escolha foi a extração do dente 38 sob anestesia geral, por via intraoral, tendo em vista a posição dentária, radiolucência e morbidade as-sociada à cirurgia. O tecido mole circundante foi enviado para análise anatomopatológica. O paciente evoluiu sem intercorrências durante avaliação pós-operatória (AU)

Ectopic teeth are frequently found, however, ectopic lower third molars are uncommon, with obscure etiology and little described in the pertinent literature. Its location has been reported in the condylar, subcondylar, mandibular notch, angle and lower edge of the mandible. Due to the importance of therapeutic planning, adequate manage-ment and variety of clinical manifestations of this condition, this study aimed to report a clinical case of an ectopic lower third molar in the region of the mandibular notch, with increased radiolucency around the crown, in a male gender pacient, 28 years old and without symptoms. Radiographic follow-up may be indicated, however, in symp-tomatic patients or patients with associated pathological changes, extraction should be considered. Therefore, the treatment of choice was the extraction of tooth 38 under general anesthesia, intraorally approach, considering the dental position, radiolucency and morbidity associated with the surgery. The surrounding soft tissue was sent for anatomopathological analysis. The patient evolved uneventfully during the postoperative evaluation (AU)

The challenges of reconstruction and rehabilitation of atrophic jaw with an autogenous graft from skull cap ­ a case report / Os desafios da reconstrução e reabilitação de mandíbula atrófica com enxerto autógeno de calota craniana ­ relato de caso

Introduction: One of the challenges of maxillofacial surgery is the rehabilitation of patients with severe bone loss, using implant-supported prostheses. This challenge is based on the small remaining bone structure, and on the need to reconstruct the structure for the rehabilitation with autogenous or exogenous grafts. Case report: We report the case of a patient with severe maxillary atrophy, where a skullcap graft was performed associated with implant placement and prosthetic completion 14 months after the start of treatment. Final considerations: We demonstrate clinical safety for the use of extraoral grafts without complications, representing a good alternative treatment for this group of patients.

Introdução: um dos desafios da cirurgia bucomaxilofacial é a reabilitação de pacientes com perda óssea severa, utilizando próteses implantossuportadas. Este desafio baseia-se na pequena estrutura óssea remanescente e na necessidade de reconstrução da estrutura para a reabilitação com enxertos autógenos ou exógenos. Relato de caso: Relatamos o caso de um paciente com atrofia maxilar grave, onde foi realizado enxerto de calota craniana associado à instalação de implante, com finalização protética 14 meses após o início do tratamento. Consideracoes finais: Demonstramos segurança clínica para o uso de enxertos extrabucais sem complicações, representando uma boa alternativa de tratamento para este grupo de pacientes.

Important aspects during advanced lingual laceration management: report of 2 cases / Aspectos importantes para o manejo das lacerações complexas da língua: relato de 2 casos

ABSTRACT Intraoral injuries affect the stomatognathic system, creating difficulties in mastication and speech articulation, especially when they affect the tongue. In this context, the quality of the suture and local care are important to proper recovery and the patient's brief return to their normal functions. Oral lacerations resulting from trauma require specific approaches. Treatments of this type of trauma may primarily be performed by professionals who conduct emergency care; however, they may require the attention of specialists. This article contains recommendations for the primary approach, treatment, and postoperative care of complex lacerations in the tongue.

RESUMO As lesões intraorais afetam o sistema estomatognático, gerando dificuldades na mastigação e na articulação da fala, principalmente quando afetam a língua. Nesse contexto, a qualidade da sutura e o cuidado local são importantes para a recuperação adequada e o breve retorno do paciente às suas funções normais. As lacerações orais resultantes de trauma requerem abordagens específicas. Os tratamentos desse tipo de trauma podem ser realizados principalmente por profissionais que realizam atendimento de emergência; no entanto, eles podem exigir a atenção de especialistas. Este artigo contém recomendações para a abordagem primária, tratamento e cuidados pós-operatórios de lacerações complexas da língua.

Influence of Implant Surfaces on Osseointegration: A Histomorphometric and Implant Stability Study in Rabbits.

The aim of this study was to evaluate the stability and osseointegration of implant with different wettability using resonance frequency analysis (RFA) and histomorphometric analysis (bone implant contact, BIC; and bone area fraction occupied, BAFO) after 2 and 4 weeks in rabbit tibiae. Thirty-two Morse taper implants (length 7 mm, diameter 3.5 mm) were divided according to surface characteristics (n=8): Neo, sandblasted and dual acid-etched; and Aq, sandblasted followed by dual acid-etched and maintained in an isotonic solution of 0.9% sodium chloride. Sixteen New Zealand rabbits were used. Two implants of each group were installed in the right and left tibiae according to the experimental periods. The RFA (Ostell(r)) was obtained immediately and after the sacrifice (2 and 4 weeks). The bone/implant blocks were processed for histomorphometric analysis. Data were analyzed using two-way ANOVA followed by Tukey's test and Pearson's correlation for ISQ, BIC and BAFO parameters (p=0.05). No significant effect of implant, period of evaluation or interaction between implant and period of evaluation was found for BIC and BAFO values (p>0.05). Only period of evaluation had significant effect for RFA values at 4 weeks (p=0.001), and at 2 weeks (p<0.001). RFA values were significantly higher at the final period of evaluation compared with those obtained at early periods. There was a significant correlation between BIC values and BAFO values (p=0.009). Both implant surfaces, Aq and Neo, were able to produce similar implant bone integration when normal cortical bone instrumentation was performed.

Reconstrução de fratura panfacial cominuta ­ relato de caso / Reconstruction of panfacial fracture - case report

RESUMO: Modelo de estudo: Relato de Caso. Importância do problema: As fraturas panfaciais recebem essa denominação quando os terços faciais apresentam fraturas concomitantes. Com frequência, essas lesões estão relacionadas a danos importantes aos tecidos moles, cominuição e perda de segmentos ósseos e/ou dentários, que podem gerar má oclusão e graves deformidades faciais, visto que etiologia de tal condição se deve à acidentes de alta dissipação de energia. O tratamento das fraturas panfaciais com o uso de fixação interna rígida permite restaurar as funções mastigatórias, bem como os contornos faciais. Comentários: O objetivo desse trabalho é relatar a reconstrução de uma fratura panfacial, envolvendo a mandíbula e com elevado grau de cominuição do complexo zigomático orbitário e do arco zigomático, em uma paciente do sexo feminino, em que acesso hemicoronal e retromandibular foram escolhidos para reconstrução e reestruturação do complexo facial. Conclusão: O correto manejo das fraturas panfaciais, é um dos grandes desafios do cirurgião buco maxilo facial, visto o nível de dificuldade para reestabelecer de maneira satisfatória as condições estéticas e funcionais existentes previamente ao trauma. Diferentes sequências de tratamento vêm sendo propostas, podendo ser utilizadas com sucesso após análise adequada do caso clínico e correta indicação. (AU)

ABSTRACT: Study model: Case Report. Importance of the problem: Panfacial fractures receive this designation when the facial thirds have concomitant fractures. Frequently, these lesions are related to important soft tissue damage, comminution, and loss of bone and/or dental segments, which may lead to malocclusion and severe facial deformities, since the etiology of such condition is due to accidents of high energy dissipation. The treatment of the panfacial fractures with the use of rigid internal fixation allows restoring the masticatory functions, as well as the facial contours. Comments: This study aimed to report the reconstruction of a panfacial fracture, involving the mandible and with a high degree of comminution of the zygomatic or zygomatic arch, in a female patient, whose hemicoronal and retromandibular access were chosen for reconstruction and restructuring of the facial complex. Conclusion: The correct management of panfacial fractures is one of the greatest challenges of the maxillofacial surgeon, given the level of difficulty to satisfactorily reestablish the aesthetic and functional conditions existing before the trauma. Different treatment sequences have been proposed to be used successfully after adequate analysis of the clinical case and correct indication. (AU)

Removal of firearm projectile from the maxillary sinus: a case report / Remoção de projétil de arma de fogo do seio maxilar: relato de caso

ABSTRACT Foreign bodies in the paranasal sinuses after critical accidents are rare occurrences that have sporadically been reported worldwide. Firearm projectiles, daggers, knives, glass fragments, stones, teeth, and wood can get lodged in the soft and hard tissues of the face. The management and prognosis in these cases depend on the composition and location of the foreign body as well as on the presence or absence of infection. Although there are reports involving the soft tissues of the face, the ethmoid, sphenoid, frontal, and maxillary sinuses are the most frequently involved sites. The main manifestation of this condition is sinusitis arising from infection and/or inflammation caused by the foreign body, which is a contaminated object. We report a case of removal of a firearm projectile located in the maxillary sinus of a 34-year-old patient under local anesthesia.

RESUMO Corpos estranhos nos seios paranasais são ocorrências raras que têm sido esporadicamente relatadas na literatura em todo o mundo. Projéteis de arma de fogo, punhais, facas, fragmentos de vidro, pedras, dentes e madeira podem ficar alojados nos tecidos moles e duros do rosto. O manejo e o prognóstico nesses casos dependem da composição e localização do corpo estranho, bem como da presença ou ausência de infecção. Embora haja relatos envolvendo os tecidos moles da face, os seios etmoidal, esfenoidal, frontal e maxilar são os locais mais frequentemente envolvidos. A principal manifestação dessa condição é sinusite decorrente de infecção e / ou inflamação causada pelo corpo estranho, que é um objeto contaminado. Relatamos um caso de remoção de um projétil de arma de fogo localizado no seio maxilar de um paciente de 34 anos de idade, sob anestesia local.

Cisto odontogênico glandular tratamento cirúrgico por marsupialização e enucleação: relato de caso / Glandular odontogenic cyst surgical treatment by marsupialization and enucleation: case report

O cisto odontogênico glandular (COG) é o cisto de desenvolvimento mais agressivo e raro dentre todos os odontogênicos, portando características epiteliais glandulares ou salivares. O presente artigo visa retratar uma abordagem mais conservadora para esta importante lesão, no sentido de minimizar a morbidade decorrente da abordagem mais radical. Paciente com 57 anos, leucoderma, assintomático e edêntulo, compareceu ao ambulatório de estomatologia com notável expansão no fundo de saco vestibular e rebordo inferior direito, com tempo indeterminado de evolução. Os exames imaginológicos revelaram uma lesão radiolúcida unilocular extensa e bem delimitada na região anterior da mandíbula. Nas condutas propedêuticas, foi realizada uma punção aspiratória positiva para líquido cístico seguido de biópsia incisional. Diante destes achados, a marsupialização foi realizada no sentido de se conseguir a redução das dimensões lesionais, seguido da enucleação com estectomia periférica após 9 meses. Nos primeiros 2 anos de proservação o paciente mantém- -se sem recidivas e em constante acompanhamento. Conclui-se que o dentista pode preferir o método conservador pela técnica de marsupialização seguida de enucleação na abordagem de extenso cisto odontogênico glandular, desde que haja colaboração do paciente nos cuidados pós-operatórios.

The glandular odontogenic cyst (GOC) is the most aggressive and rare cyst of development among all odontogenics, with glandular or salivary epithelial characteristics. This article aims to portray a more conservative approach to this important lesion, in order to minimize the morbidity resulting from the more radical approach. Patient 57 years-old, leucoderma, asymptomatic and edentulous, attended the stomatology outpatient clinic with a remarkable expansion in the vestibular bag fundus and lower right border, with indeterminate evolution time. Imaging examinations revealed an extensive and well delimited unilocular radiolucent lesion in the anterior region of the mandible. In the propaedeutic procedures, a positive aspiration puncture was performed for cystic fluid followed by incisional biopsy. In view of these findings, marsupialization was performed in order to reduce lesion dimensions, followed by enucleation with peripheral ostectomy after 9 months. In the first 2 years of proservation, the patient remains without relapses and in constant follow-up. It is concluded that the dentist may prefer the conservative method by the marsupialization technique followed by enucleation in the approach of extensive glandular odontogenic cyst, provided there is collaboration of the patient in the postoperative care.

Tratamento cirúrgico de terceiro molar inferior invertido: relato de caso / Treatment of third invested lower molar: case report

A presença de terceiros molares invertidos se apresenta como uma condição pouco relatada na literatura. Diversas hipóteses têm sido propostas para explicar o deslocamento destes elementos, entretanto suas causas e tratamentos permanecem incertos. O objetivo deste trabalho é relatar um caso clínico de impacção invertida de terceiro molar inferior direito, onde optou-se pela exodontia sob anestesia local com osteotomia conservadora e exérese total do elemento em paciente do sexo feminino de 52 anos. Terceiros molares com esta variação de erupção são raros na clínica, sendo geralmente visualizados em exames radiográficos de rotina e observados clinicamente após início de sintomatologia. Diversos tratamentos têm sido propostos, variando de abordagem cirúrgica, ao acompanhamento de longo prazo. A abordagem intraoral associada a uma conduta conservadora tem se mostrado o tratamento de escolha na maioria dos casos. Entretanto, a escolha do planejamento dependerá, dentre outros fatores, da sintomatologia do paciente e a presença de patologias associadas, sempre optando-se pela técnica que promoverá menor morbidade operatória e melhor resolubilidade do caso(AU)

The presence of inverted third molars presents as a condition poorly reported in the literature. Several hypotheses have been proposed to explain the displacement of these elements, however their causes and treatments remain uncertain. The objective of this study is to report a clinical case of inverted impaction of the right lower third molar, where it was chosen exodontia under local anesthesia with conservative osteotomy and total exeresis of the element in a 52-year-old female patient. Third molars with this variation of eruption are rare in the clinic and are usually visualized in routine radiographic examinations and observed clinically after start symptomatology. Several treatments have been proposed, ranging from a surgical approach to long-term follow-up. The intraoral approach associated with conservative management has been shown to be the treatment of choice in most cases. However, the choice of planning will depend, among other factors, on the patient's symptoms and the presence of associated pathologies, always opting for the technique that will promote less operative morbidity and better solubility of the case(AU)

Análise eletromiográfica do efeito da fisioterapia no músculo masseter em pós-operatório de politrauma de face / Electromyographic analysis of the effect of physical therapy on the masseter muscle in post-operative facial polytrauma

Em situações de acidente, os traumas faciais têm ocupado lugar de destaque, e as fraturas mandibulares compreendem o maior percentual de injúrias tratadas pelos cirurgiões bucomaxilofaciais. Intervenções fisioterapêuticas vêm sendo somadas à reabilitação pós-operatória, otimizando a atividade muscular pós-trauma, colaborando na recuperação das funções mastigatórias, de fonação, deglutição e posturais. Objetivo: o presente estudo objetivou comparar a evolução longitudinal da atividade elétrica do músculo masseter por meio de exame eletromiográfico em um indivíduo politraumatizado submetido à fisioterapia e outro com fratura de mandíbula sem tratamento fisioterapêutico. Sujeitos e método: para tal pesquisa, analisou-se um voluntário politraumatizado submetido a tratamento fisioterapêutico, um voluntário com fratura de mandíbula sem tratamento fisioterapêutico e três voluntários sem fraturas como grupo controle. Foi realizada uma primeira coleta de dados eletromiográficos nos primeiros dias após alta do serviço de cirurgia responsável pelo tratamento das fraturas e uma segunda coleta 60 dias após. No indivíduo submetido ao tratamento fisioterápico, realizou-se ainda uma terceira coleta após 90 dias. Resultados: o voluntário politraumatizado submetido ao tratamento fisioterapêutico, em 90 dias, obteve atividade elétrica do músculo masseter, semelhante ao grupo controle. Já o voluntário com fretura mandibular não submetido ao tratamento fisioterapêutico apresentou resultados semelhantes ao grupo controle após 60 dias de alta hospitalar. Considerações finais: conclui-se que a intervenção fisioterapêutica em pacientes politraumatizados é de grande relevância, devolvendo a condição muscular fisiológica de mastigação, no que tange à atividade elétrica, num prazo de até 90 dias, apresentando, além disso, vantagens na redução da sintomatologia desarmonizadora da função.(AU)

In cases of accident, facial trauma has stood out and mandibular fractures comprise the highest rate of injuries treated by oral and maxillofacial surgeons. Physiotherapeutic interventions have been added to postoperative rehabilitation, optimizing post-trauma muscle activity, aiding the recovery of masticatory, phonation, swallowing, and postural functions. Objective: the present study aimed to compare the longitudinal evolution of the electrical activity of the masseter muscle through electromyographic examination in a polytraumatized individual subjected to physical therapy and another individual with mandibular fracture without physical therapy. Subjects and method: the study analyzed a polytraumatized volunteer subjected to physical therapy treatment, a volunteer with mandibular fracture without physical therapy treatment, and three volunteers without fractures as control group. A first electromyographic data collection was performed in the first days after the discharge from the surgery department responsible for the treatment of fractures, and a second collection occurred 60 days later. In the individual subjected to physiotherapeutic treatment, a third collection was performed 90 days later. Results: the polytraumatized volunteer subjected to the physiotherapeutic treatment obtained, in 90 days, electrical activity of the masseter muscle similar to the control group. The volunteer with mandibular fracture not subjected to physical therapy presented results similar to the control group 60 days after hospital discharge. Final considerations: it is concluded that the physiotherapeutic intervention in polytraumatized patients is of great relevance, returning the physiological muscular condition of chewing, regarding the electrical activity, within a period of up to 90 days, also presenting advantages in the reduction of the function disharmonizing symptomatology.(AU)

The approach of ameloblastoma of the mandible: a case treated by hyperbaric oxygen therapy and bone graft reconstruction.

BACKGROUND: Reconstruction of mandibular defects after tumor resection is a challenge to the head and neck surgeon because of associated functional and esthetic problems. The intention of mandibular reconstructive surgery is to achieve maximum possible functionality, which means the restoration of masticatory function and speech with a good esthetic result. Hyperbaric oxygen therapy (HBO) is already a well-accepted adjunct in the treatment of extensive bone defects. It has been shown to enhance osteogenesis and improve soft tissue wound healing in a variety of circumstances. CASE REPORT: The following case report describes a 29-year-old woman who was diagnosed with mandibular ameloblastoma. The treatment of choice is resection with mandibular base maintenance. The patient underwent 10 sessions of hyperbaric oxygen therapy and subsequent nonvascularized iliac crest graft. Six months after, mandibular reconstruction is possible to observe the preservation of mandibular contouring and facial esthetics. A panoramic radiograph revealed good positioning of the bone graft and volume maintenance. DISCUSSION: The mandibular reconstruction is extremely important for the rehabilitation of the patient who underwent bone resection. The restoration of mandibular function and facial esthetics is essential to maintain the quality of life. The use of HBO in mandibular reconstruction is an important adjunct to successful treatment, however, more studies are needed to establish the best modalities of rehabilitation.

Abordagem clínico-cirúrgica de infecção complexa Em região maxilo-facial: relato de caso / Clinical-surgical approach to complex infection in Maxillofacial region: a case report

Infecções de origem odontogênica possuem o potencial de disseminar-se pelos espaços faciais e comprometer a vida do paciente, devendo, portanto ser tratadas como uma urgência e requerem intervenção imediata. Algumas comorbidades como deficiência imunológica, diabetes e cirrose hepática, podem predispor ao agravamento da infecção e dificultar seu tratamento. Neste relato de caso apresentamos um paciente de 66 anos de idade, com odontalgia em região de molares superiores. Ao exame clínico foi observado sinais flogísticos em fundo de vestíbulo na região de molares e pré-molares superiores direito. Foi iniciada antibioticoterapia por via oral seguida pela extração dos dentes comprometidos. Após 12 horas do primeiro atendimento, o paciente evoluiu com edema extenso de consistência lenhosa em hemiface direita, trismo severo, disfagia, dislalia e dispneia leve. O paciente foi submetido à drenagem cirúrgica do abscesso sob anestesia geral e 72 horas pós-procedimento evoluiu com insuficiência renal aguda, síndrome de abstinência alcoólica, hipertensão arterial sistêmica de difícil controle e piora do quadro infeccioso. Foram solicitados novos exames imaginológicos onde foi observada uma lesão apical inicialmente não diagnosticada associada ao dente 47. O paciente foi submetido à nova drenagem e remoção do dente 47. Após 10 dias do início da nova terapia antibiótica o paciente recebeu alta hospitalar. O mesmo permaneceu em acompanhamento ambulatorial recebendo alta definitiva após 30 dias de acompanhamento em bom estado geral. Para evitar recorrências e instituir um tratamento definitivo para infecções de origem odontogênica, é importante, além da intervenção imediata, um exame minucioso eliminando possíveis focos de infecção

Severe odontogenic infections have the potential to spread through facial spaces and compromise the patient´s life, thus should be treated as an emergency requiring immediate intervention. Some comorbidities such as immunological deficiency, diabetes and liver cirrhousis, can predispose worsening of infection making it difficult to treat. In this case report we present a 66 year old patient with toothache in the region of upper molars. Clinical examination revealed phlogistic signs in the vestibule fundus region of the upper right molars and premolars. Oral antibiotic therapy was initiated followed by extraction of the involved teeth. After 12 hours of the initial treatment, the patient developed extensive edema with woody consistency in right hemiface, severe trismus, dysphagia, dyslalia and slight dyspnoea. The patient underwent surgical drainage of the abscess under general anesthesia. After 72 hours of this procedure he evolved with acute renal failure, alcohol withdrawal syndrome, systemic arterial hypertension of difficult control and worsening of the infectious condition. New imaging exams were requested where an initial undetected apical lesion associated with tooth 47 was observed. The patient was submitted to new drainage and removal of the tooth 47. After 10 days of the start of the new antibiotic therapy the patient was discharged from hospital. The patient remained in outpatient follow-up receiving definitive discharge after 30 days of followup in good general condition. In order to avoid recurrences and to institute a definitive treatment for odontogenic infections, it is important, besides the immediate intervention, a thorough examination eliminating possible foci of infection