RESUMEN
BACKGROUND: Many researchers have studied the relationship between facial asymmetry and cranial base morphology, but they have failed to reach a consensus. In this study, we aimed to verify whether the cranial base is involved in hemifacial microsomia (HFM). METHODS: We included 66 patients with HFM who were treated at the Plastic and Reconstructive Surgery Department of Shanghai Ninth People's Hospital from January 2013 to October 2016. The patients were divided into three groups according to Pruzansky and OMENS classifications, separately. The controls were 20 patients diagnosed with mandibular angle hypertrophy but with no facial asymmetry. Angular and linear measurements of the cranial base were obtained for all patients. RESULTS: The two classification methods yielded similar results. The intersection angle between two planes showed differences in the severe group. In the moderate and severe groups, the middle and posterior cranial angles were significantly different and the CIP and SP lengths were shorter in the affected side. Landmarks such as the carotid canal and internal acoustic canal could be considered as references. CONCLUSIONS: The cranial base is involved in hemifacial microsomia. This relationship supports the hypothesis of HFM pathogenesis and opens new avenues to classification methods.