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1.

Nanoscale Probing of Liposome Encapsulating Drug Nanocrystal Using Atomic Force Microscopy-Infrared Spectroscopy.

Khanal, Dipesh; Khatib, Isra; Ruan, Juanfang; Cipolla, David; Dayton, Francis; Blanchard, James D; Chan, Hak-Kim; Chrzanowski, Wojciech.

Anal Chem ; 92(14): 9922-9931, 2020 07 21.

Article En | MEDLINE | ID: mdl-32551576

2.

Tuning Ciprofloxacin Release Profiles from Liposomally Encapsulated Nanocrystalline Drug.

Cipolla, David; Wu, Huiying; Eastman, Simon; Redelmeier, Tom; Gonda, Igor; Chan, Hak-Kim.

Pharm Res ; 33(11): 2748-62, 2016 11.

Article En | MEDLINE | ID: mdl-27439506

3.

The effect of actuator nozzle designs on the electrostatic charge generated in pressurised metered dose inhaler aerosols.

Chen, Yang; Young, Paul M; Fletcher, David F; Chan, Hak Kim; Long, Edward; Lewis, David; Church, Tanya; Traini, Daniela.

Pharm Res ; 32(4): 1237-48, 2015 Apr.

Article En | MEDLINE | ID: mdl-25270573

4.

NanoXCT: a novel technique to probe the internal architecture of pharmaceutical particles.

Wong, Jennifer; D'Sa, Dexter; Foley, Matthew; Chan, John Gar Yan; Chan, Hak-Kim.

Pharm Res ; 31(11): 3085-94, 2014 Nov.

Article En | MEDLINE | ID: mdl-24867423

5.

Aerosol performance and long-term stability of surfactant-associated liposomal ciprofloxacin formulations with modified encapsulation and release properties.

Cipolla, David; Wu, Huiying; Gonda, Igor; Chan, Hak-Kim.

AAPS PharmSciTech ; 15(5): 1218-27, 2014 Oct.

Article En | MEDLINE | ID: mdl-24889736

6.

Effects of the deformation and size of the upper airway on the deposition of aerosols.

Gou, Dazhao; Zhu, Qixuan; Chan, Hak-Kim; Kourmatzis, Agisilaos; Cheng, Shaokoon; Yang, Runyu.

Int J Pharm ; 657: 124165, 2024 May 25.

Article En | MEDLINE | ID: mdl-38663643

7.

Does the United States Pharmacopeia throat introduce de-agglomeration of carrier-free powder from inhalers?

Tang, Patricia; Kwok, Philip Chi Lip; Tong, Zhenbo; Yang, Runyu; Raper, Judy Agnes; Chan, Hak-Kim.

Pharm Res ; 29(7): 1797-807, 2012 Jul.

Article En | MEDLINE | ID: mdl-22327971

8.

Topical liquid formulation of bacteriophages for metered-dose spray delivery.

Chang, Rachel Yoon Kyung; Okamoto, Yuko; Morales, Sandra; Kutter, Elizabeth; Chan, Hak-Kim.

Eur J Pharm Biopharm ; 177: 1-8, 2022 Aug.

Article En | MEDLINE | ID: mdl-35671913

9.

Isoniazid proliposome powders for inhalation-preparation, characterization and cell culture studies.

Rojanarat, Wipaporn; Changsan, Narumon; Tawithong, Ekawat; Pinsuwan, Sirirat; Chan, Hak-Kim; Srichana, Teerapol.

Int J Mol Sci ; 12(7): 4414-34, 2011.

Article En | MEDLINE | ID: mdl-21845086

10.

Storage stability of inhalable, controlled-release powder formulations of ciprofloxacin nanocrystal-containing liposomes.

Khatib, Isra; Ke, Wei-Ren; Cipolla, David; Chan, Hak-Kim.

Int J Pharm ; 605: 120809, 2021 Aug 10.

Article En | MEDLINE | ID: mdl-34144139

11.

Modeling of a spray drying method to produce ciprofloxacin nanocrystals inside the liposomes utilizing a response surface methodology: Box-Behnken experimental design.

Khatib, Isra; Chow, Michael Y T; Ruan, Juanfang; Cipolla, David; Chan, Hak-Kim.

Int J Pharm ; 597: 120277, 2021 Mar 15.

Article En | MEDLINE | ID: mdl-33540024

12.

Hydrogel formulations containing non-ionic polymers for topical delivery of bacteriophages.

Chang, Rachel Yoon Kyung; Okamoto, Yuko; Morales, Sandra; Kutter, Elizabeth; Chan, Hak-Kim.

Int J Pharm ; 605: 120850, 2021 Aug 10.

Article En | MEDLINE | ID: mdl-34216771

13.

Controlled release antibiotics for dry powder lung delivery.

Adi, Handoko; Young, Paul Michael; Chan, Hak-Kim; Salama, Rania; Traini, Daniela.

Drug Dev Ind Pharm ; 36(1): 119-26, 2010 Jan.

Article En | MEDLINE | ID: mdl-19656005

14.

In vitro-in vivo correlations (IVIVCs) of deposition for drugs given by oral inhalation.

Newman, Stephen P; Chan, Hak-Kim.

Adv Drug Deliv Rev ; 167: 135-147, 2020 12.

Article En | MEDLINE | ID: mdl-32593641

15.

Topical application of bacteriophages for treatment of wound infections.

Chang, Rachel Yoon Kyung; Morales, Sandra; Okamoto, Yuko; Chan, Hak-Kim.

Transl Res ; 220: 153-166, 2020 06.

Article En | MEDLINE | ID: mdl-32268129

16.

Formation of ciprofloxacin nanocrystals within liposomes by spray drying for controlled release via inhalation.

Khatib, Isra; Tang, Patricia; Ruan, Juanfang; Cipolla, David; Dayton, Francis; Blanchard, James D; Chan, Hak-Kim.

Int J Pharm ; 578: 119045, 2020 Mar 30.

Article En | MEDLINE | ID: mdl-31981702

17.

Optimization of inhalable liposomal powder formulations and evaluation of their in vitro drug delivery behavior in Calu-3 human lung epithelial cells.

Yu, Shihui; Yuan, Huiya; Chai, Guihong; Peng, Kuan; Zou, Peizhi; Li, Xuxi; Li, Jian; Zhou, Fanfan; Chan, Hak-Kim; Zhou, Qi Tony.

Int J Pharm ; 586: 119570, 2020 Aug 30.

Article En | MEDLINE | ID: mdl-32593649

18.

Polymeric Nanocarriers With Mucus-Diffusive and Mucus-Adhesive Properties to Control Pharmacokinetic Behavior of Orally Dosed Cyclosporine A.

Sato, Hideyuki; Kaneko, Yuuki; Yamada, Kohei; Ristroph, Kurt D; Lu, Hoang D; Seto, Yoshiki; Chan, Hak-Kim; Prud'homme, Robert K; Onoue, Satomi.

J Pharm Sci ; 109(2): 1079-1085, 2020 02.

Article En | MEDLINE | ID: mdl-31697948

19.

Ciprofloxacin nanocrystals liposomal powders for controlled drug release via inhalation.

Khatib, Isra; Khanal, Dipesh; Ruan, Juanfang; Cipolla, David; Dayton, Francis; Blanchard, James D; Chan, Hak-Kim.

Int J Pharm ; 566: 641-651, 2019 Jul 20.

Article En | MEDLINE | ID: mdl-31202900

20.

Preparation and characterisation of controlled release co-spray dried drug-polymer microparticles for inhalation 1: influence of polymer concentration on physical and in vitro characteristics.

Salama, Rania; Hoe, Susan; Chan, Hak-Kim; Traini, Daniela; Young, Paul M.

Eur J Pharm Biopharm ; 69(2): 486-95, 2008 Jun.

Article En | MEDLINE | ID: mdl-18226880

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