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1.

Chemical modification of bradykinin-polymer conjugates for optimum delivery of nanomedicines to tumors.

Appiah, Enoch; Nakamura, Hideaki; Assumang, Anthony; Etrych, Tomás; Haratake, Mamoru.

Nanomedicine ; 57: 102744, 2024 Apr.

Article En | MEDLINE | ID: mdl-38460653

2.

Therapeutic activity and biodistribution of a nano-sized polymer-dexamethasone conjugate intended for the targeted treatment of rheumatoid arthritis.

Rubanová, Daniela; Skoroplyas, Svitlana; Libánská, Alena; Randárová, Eva; Bryja, Josef; Chorvátová, Michaela; Etrych, Tomás; Kubala, Lukás.

Nanomedicine ; 55: 102716, 2024 Jan.

Article En | MEDLINE | ID: mdl-38738529

3.

HPMA copolymer conjugated 5-aminolevulinic acid exhibits superior efficacy for photodynamic therapy with tumor-responsive and targeting properties.

Islam, Rayhanul; Kotalík, Kevin; Subr, Vladimír; Gao, Shanghui; Zhou, Jian-Rong; Yokomizo, Kazumi; Etrych, Tomás; Fang, Jun.

Nanomedicine ; 48: 102636, 2023 02.

Article En | MEDLINE | ID: mdl-36549553

4.

Simultaneous Delivery of Doxorubicin and Protease Inhibitor Derivative to Solid Tumors via Star-Shaped Polymer Nanomedicines Overcomes P-gp- and STAT3-Mediated Chemoresistance.

Kostka, Libor; Sivák, Ladislav; Subr, Vladimír; Kovárová, Jirina; Sírová, Milada; Ríhová, Blanka; Sedlacek, Radislav; Etrych, Tomás; Kovár, Marek.

Biomacromolecules ; 23(6): 2522-2535, 2022 06 13.

Article En | MEDLINE | ID: mdl-35584053

5.

Polymer nanomedicines with enzymatically triggered activation: A comparative study of in vitro and in vivo anti-cancer efficacy related to the spacer structure.

Pechar, Michal; Pola, Robert; Studenovský, Martin; Bláhová, Markéta; Grosmanová, Eliska; Dydowiczová, Aneta; Filipová, Marcela; Islam, Rayhanul; Gao, Shanghui; Fang, Jun; Etrych, Tomás.

Nanomedicine ; 46: 102597, 2022 11.

Article En | MEDLINE | ID: mdl-36064033

6.

Glycopolymers for Efficient Inhibition of Galectin-3: In Vitro Proof of Efficacy Using Suppression of T Lymphocyte Apoptosis and Tumor Cell Migration.

Filipová, Marcela; Bojarová, Pavla; Rodrigues Tavares, Marina; Bumba, Ladislav; Elling, Lothar; Chytil, Petr; Gunár, Kristýna; Kren, Vladimír; Etrych, Tomás; Janousková, Olga.

Biomacromolecules ; 21(8): 3122-3133, 2020 08 10.

Article En | MEDLINE | ID: mdl-32697592

7.

High-Affinity N-(2-Hydroxypropyl)methacrylamide Copolymers with Tailored N-Acetyllactosamine Presentation Discriminate between Galectins.

Tavares, Marina Rodrigues; Bláhová, Markéta; Sedláková, Lieselotte; Elling, Lothar; Pelantová, Helena; Konefal, Rafal; Etrych, Tomás; Kren, Vladimír; Bojarová, Pavla; Chytil, Petr.

Biomacromolecules ; 21(2): 641-652, 2020 02 10.

Article En | MEDLINE | ID: mdl-31904940

8.

Polymer Cancerostatics Targeted by Recombinant Antibody Fragments to GD2-Positive Tumor Cells.

Pola, Robert; Král, Vlastimil; Filippov, Sergey K; Kaberov, Leonid; Etrych, Tomás; Sieglová, Irena; Sedlácek, Juraj; Fábry, Milan; Pechar, Michal.

Biomacromolecules ; 20(1): 412-421, 2019 01 14.

Article En | MEDLINE | ID: mdl-30485077

9.

Bloodstream Stability Predetermines the Antitumor Efficacy of Micellar Polymer-Doxorubicin Drug Conjugates with pH-Triggered Drug Release.

Chytil, Petr; Sírová, Milada; Kudlácová, Júlia; Ríhová, Blanka; Ulbrich, Karel; Etrych, Tomás.

Mol Pharm ; 15(9): 3654-3663, 2018 09 04.

Article En | MEDLINE | ID: mdl-29543465

10.

N-(2-Hydroxypropyl)methacrylamide-Based Linear, Diblock, and Starlike Polymer Drug Carriers: Advanced Process for Their Simple Production.

Koziolová, Eva; Kostka, Libor; Kotrchová, Lenka; Subr, Vladimír; Konefal, Rafal; Nottelet, Benjamin; Etrych, Tomás.

Biomacromolecules ; 19(10): 4003-4013, 2018 10 08.

Article En | MEDLINE | ID: mdl-30180562

11.

Macromolecular pHPMA-Based Nanoparticles with Cholesterol for Solid Tumor Targeting: Behavior in HSA Protein Environment.

Zhang, Xiaohan; Niebuur, Bart-Jan; Chytil, Petr; Etrych, Tomas; Filippov, Sergey K; Kikhney, Alexey; Wieland, D C Florian; Svergun, Dmitri I; Papadakis, Christine M.

Biomacromolecules ; 19(2): 470-480, 2018 02 12.

Article En | MEDLINE | ID: mdl-29381335

12.

Iterative Photoinduced Chain Functionalization as a Generic Platform for Advanced Polymeric Drug Delivery Systems.

Samad, Assala Al; Bethry, Audrey; Janouskova, Olga; Ciccione, Jérémie; Wenk, Christiane; Coll, Jean-Luc; Subra, Gilles; Etrych, Tomas; Omar, Fawaz El; Bakkour, Youssef; Coudane, Jean; Nottelet, Benjamin.

Macromol Rapid Commun ; 39(3)2018 Feb.

Article En | MEDLINE | ID: mdl-29094415

13.

Metastatic spread inhibition of cancer cells through stimuli-sensitive HPMA copolymer-bound actinonin nanomedicines.

Kousalová, Jana; Sírová, Milada; Kostka, Libor; Subr, Vladimír; Kovárová, Jirina; Behalová, Katerina; Studenovský, Martin; Kovár, Marek; Etrych, Tomás.

Nanomedicine ; 44: 102578, 2022 08.

Article En | MEDLINE | ID: mdl-35779856

14.

Pronounced Cellular Uptake of Pirarubicin versus That of Other Anthracyclines: Comparison of HPMA Copolymer Conjugates of Pirarubicin and Doxorubicin.

Nakamura, Hideaki; Koziolová, Eva; Chytil, Petr; Tsukigawa, Kenji; Fang, Jun; Haratake, Mamoru; Ulbrich, Karel; Etrych, Tomás; Maeda, Hiroshi.

Mol Pharm ; 13(12): 4106-4115, 2016 12 05.

Article En | MEDLINE | ID: mdl-27934482

15.

Biodegradable Micellar HPMA-Based Polymer-Drug Conjugates with Betulinic Acid for Passive Tumor Targeting.

Lomkova, Ekaterina A; Chytil, Petr; Janousková, Olga; Mueller, Thomas; Lucas, Henrike; Filippov, Sergey K; Trhlíková, Olga; Aleshunin, Pavel A; Skorik, Yury A; Ulbrich, Karel; Etrych, Tomás.

Biomacromolecules ; 17(11): 3493-3507, 2016 11 14.

Article En | MEDLINE | ID: mdl-27636143

16.

[Missile-Type Tumor-Targeting Polymer Drug, P-THP, Seeks Tumors via Three Different Steps Based on the EPR Effect].

Maeda, Hiroshi; Fang, Jun; Ulbrich, Karel; Etrych, Tomás; Nakamura, Hideaki.

Gan To Kagaku Ryoho ; 43(5): 549-57, 2016 May.

Article Ja | MEDLINE | ID: mdl-27210083

17.

Thermoresponsive Polymer Micelles as Potential Nanosized Cancerostatics.

Laga, Richard; Janousková, Olga; Ulbrich, Karel; Pola, Robert; Blazková, Jana; Filippov, Sergey K; Etrych, Tomás; Pechar, Michal.

Biomacromolecules ; 16(8): 2493-505, 2015 Aug 10.

Article En | MEDLINE | ID: mdl-26153904

18.

Anti-Lymphoma Efficacy Comparison of Anti-Cd20 Monoclonal Antibody-Targeted and Non-Targeted Star-Shaped Polymer-Prodrug Conjugates.

Lidický, Ondrej; Janousková, Olga; Strohalm, Jirí; Alam, Mahmudul; Klener, Pavel; Etrych, Tomás.

Molecules ; 20(11): 19849-64, 2015 Nov 04.

Article En | MEDLINE | ID: mdl-26556320

19.

Hybrid Macromolecular Constructs as a Platform for Spectral Nanoprobes for Advanced Cellular Barcoding in Flow Cytometry.

Kudlácová, Júlia; Kuzílková, Daniela; Bárta, Frantisek; Brdicková, Nadezda; Vávrová, Adéla; Kostka, Libor; Hovorka, Ondrej; Kalina, Tomás; Etrych, Tomás.

Macromol Biosci ; 24(2): e2300306, 2024 Feb.

Article En | MEDLINE | ID: mdl-37691533

20.

Iridium-based Polymeric Multifunctional Imaging Tools for Biochemistry.

Sansee, Anuson; Kostka, Libor; Marcalíková, Adéla; Kudlácová, Júlia; Sedlák, Frantisek; Kotrchová, Lenka; Sácha, Pavel; Etrych, Tomás; Kielar, Filip.

Chempluschem ; 89(5): e202300647, 2024 May.

Article En | MEDLINE | ID: mdl-38217401

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