User acceptance of a touchless sterile system to control virtual orthodontic study models.

INTRODUCTION: In this article, we present an evaluation of user acceptance of our innovative hand-gesture-based touchless sterile system for interaction with and control of a set of 3-dimensional digitized orthodontic study models using the Kinect motion-capture sensor (Microsoft, Redmond, Wash). METHODS: The system was tested on a cohort of 201 participants. Using our validated questionnaire, the participants evaluated 7 hand-gesture-based commands that allowed the user to adjust the model in size, position, and aspect and to switch the image on the screen to view the maxillary arch, the mandibular arch, or models in occlusion. Participants' responses were assessed using Rasch analysis so that their perceptions of the usefulness of the hand gestures for the commands could be directly referenced against their acceptance of the gestures. Their perceptions of the potential value of this system for cross-infection control were also evaluated. RESULTS: Most participants endorsed these commands as accurate. Our designated hand gestures for these commands were generally accepted. We also found a positive and significant correlation between our participants' level of awareness of cross infection and their endorsement to use this system in clinical practice. CONCLUSIONS: This study supports the adoption of this promising development for a sterile touch-free patient record-management system.

Carica papaya induces in vitro thrombopoietic cytokines secretion by mesenchymal stem cells and haematopoietic cells.

BACKGROUND: Use of Carica papaya leaf extracts, reported to improve thrombocyte counts in dengue patients, demands further analysis on the underlying mechanism of its thrombopoietic cytokines induction METHODS: In vitro cultures of peripheral blood leukocytes (PBL) and stem cells from human exfoliated deciduous teeth (SHED) were treated with unripe papaya pulp juice (UPJ) to evaluate its potential to induce thrombopoietic cytokines (IL-6 and SCF) RESULTS: In vitro scratch gap closure was significantly faster (p < .05) in SHED culture treated with UPJ. IL-6 concentration was significantly increased (p < .05) in SHED and PBL culture supernatant when treated with UPJ. SCF synthesis in SHED culture was also significantly increased (p < .05) when treated with UPJ CONCLUSION: In vitro upregulated synthesis of IL -6 and SCF both in PBL and SHED reveals the potential mechanism of unripe papaya to induce thrombopoietic cytokines synthesis in cells of hematopoietic and mesenchymal origin.

Is the burden of oral diseases higher in urban disadvantaged community compared to the national prevalence?

BACKGROUND: The urban low income has often been assumed to have the greatest dental treatment needs compared to the general population. However, no studies have been carried out to verify these assumptions. This study was conducted to assess whether there was any difference between the treatment needs of an urban poor population as compared to the general population in order to design an intervention programme for this community. METHODS: A random sampling of living quarters (households) in the selected areas was done. 586 adults over 19 years old living in these households were clinically examined using World Health Organization (WHO) Oral Health Survey criteria 4th edition (1997). RESULTS: The overall prevalence of dental caries, periodontal disease, denture wearers and temporomandibular joint problems were 70.5%, 97.1%, 16.7% and 26%, respectively. The majority (80.5%) needed some form of dental treatment. The highest treatment needs were found in the oldest age group while the lowest were in the youngest group (19-29 years) (p = 0.000). The most prevalent periodontal problem was calculus; regardless of gender, ethnicity and age. Significantly more females (20.5%) wore prosthesis than males (11.1%) (p = 0.003). Prosthetic status and need significantly increased with age (p = 0.000). About one in four adults had Temporo-Mandibular Joint (TMJ) problems. Overall, it was surprising to note that the oral disease burden related to caries, prosthetic status and treatment need were lower in this population as compared to the national average (NOHSA, 2010). However, their periodontal disease status and treatment needs were higher compared to the national average indicating a poor oral hygiene standard. CONCLUSIONS: The evidence does not show that the overall oral disease burden and treatment needs in this urban disadvantaged adult population as higher than the national average, except for periodontal disease. The older age groups and elderly were identified as the most in need for oral health intervention and promotion. An integrated health intervention programme through a multisectoral common risk factor approach in collaboration with the Faculties of Medicine, Dentistry and other agencies is needed for the identified target group.

Effect of operators' experience and cement space on the marginal fit of an in-office digitally produced monolithic ceramic crown system.

OBJECTIVES: To investigate the marginal accuracy of Cerec three-dimensional (3D) all-ceramic crowns, in terms of gap and overhang, and to analyze the "operators' experience" and "cement space" effects on the marginal fit. METHOD AND MATERIALS: Thirty virtual models were obtained from a metal master die by scanning by three different operators: operator 1 (novice), operator 2 (beginner), and operator 3 (expert) (n = 10). These were further divided into two subgroups of five each, based on the cement space settings: 10 µm and 20 µm. Monolithic ceramic crowns (n = 10) were designed and milled for each virtual model and subjected to marginal gap and overhang evaluation at six designated margin locations. The influence of operators' experience and cement space on the marginal fit of the crowns was assessed by performing Box tests and MANOVA (multiple analysis of variance) (α = .05). Kruskal Wallis test was also used to analyze the interactions between the operators' experience and the cement space. RESULTS: The overall mean ± SD marginal gaps and overhangs for the Cerec 3D crowns, were 154 ± 56 µm and 74 ± 74 µm for novice, 158 ± 53 µm and 86 ± 66 µm for beginner, and 155 ± 52 µm and 47 ± 76 µm for expert, respectively. The MANOVA and Kruskal Wallis tests found no significant differences (P > .05) between the operators, in terms of gap and overhang, for all cement settings. CONCLUSION: The operator experience did not seem to influence the marginal accuracy of Cerec 3D fabricated crowns.