Detalhe da pesquisa
1.
Lipid nanoparticle structure and delivery route during pregnancy dictate mRNA potency, immunogenicity, and maternal and fetal outcomes.
Proc Natl Acad Sci U S A
; 121(11): e2307810121, 2024 Mar 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-38437545
2.
The mixing method used to formulate lipid nanoparticles affects mRNA delivery efficacy and organ tropism.
Eur J Pharm Biopharm
; 192: 126-135, 2023 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-37838143
3.
The replacement of helper lipids with charged alternatives in lipid nanoparticles facilitates targeted mRNA delivery to the spleen and lungs.
J Control Release
; 345: 819-831, 2022 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-35346768
4.
Lipid nanoparticle chemistry determines how nucleoside base modifications alter mRNA delivery.
J Control Release
; 341: 206-214, 2022 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34801660