1.
Methods Mol Biol
; 1963: 25-29, 2019.
Artigo
em Inglês
| MEDLINE
| ID: mdl-30875041
RESUMO
We provide a DNA extraction protocol optimized for the recovery of highly fragmented molecules preserved within bones and teeth. In this method, the hard tissue matrix is degraded using an EDTA/Proteinase K lysis buffer, and the DNA is purified using spin columns with silica membranes. This method efficiently recovers molecules as short as 35 base-pairs long.