RESUMO
OBJECTIVES: Ameloblastoma is a benign odontogenic neoplasm with an origin reputed to reactivation of odontogenic structures. Histological classification is based on microscopic features and architectural distribution of neoplastic cells. The importance of squamous metaplasia and keratinization has been disputed in ameloblastomas. Clinical and histopathological aspects were evaluated of 85 ameloblastomas, with attention to keratinization and squamous metaplasia features. STUDY DESIGN: Clinical-demographical information of 85 ameloblastomas were gleaned from the medical records. Microscopic analysis of all cases was carried out with emphasis on keratinization aspects of each tumor. RESULTS: Most ameloblastomas (54.12%) were diagnosed in males with a mean age of 37 years. Fifty-six patients were Caucasians (65.88%) and the mandible was affected in 68 (89.4%) cases. Most cases analyzed presented areas of squamous metaplasia/keratinization. Recurrence was detected in 16 cases; this was not related to keratinization aspects of the tumor. CONCLUSIONS: Keratinization is a common feature in ameloblastomas with no impact in tumor behavior.
Assuntos
Ameloblastoma/patologia , Neoplasias Maxilomandibulares/patologia , Queratinas/metabolismo , Adolescente , Adulto , Idoso , Idoso de 80 Anos ou mais , Criança , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Adulto JovemRESUMO
O cisto ósseo simples, lesão incomum dentre as patologias da cavidade oral, apresenta uma etiologia ainda inconclusiva, o que se pode constatar frente à variedade de termos que têm sido utilizados para descrever tal condição. Clinicamente, este se apresenta de forma assintomática, sendo na grande maioria dos casos, diagnosticado a partir de um achado ra- diográfico. Apresenta uma predileção pela mandíbula, em regiões dentadas, caracterizando-se radiograficamente como uma lesão unilocular sem expansão das paredes ósseas circundantes. Este artigo visa relatar dois casos clínicos de cistos ósseos simples diagnosticados como atípicos devido ao acometimento do osso mandibular em regiões edêntulas, sendo que em um dos casos apresentou expansão das paredes ósseas; aspecto que, diverge do comumente encontrado na literatura. Ambos os casos clínicos foram submetidos à curetagem e promoção do sangramento das paredes ósseas, com subseqüente formação de um coágulo sanguíneo estável. Como visto na maioria dos casos relatados na literatura, a curetagem da região acometida pelo cisto ósseo traumático apresenta-se como uma alternativa terapêutica extremamente eficaz, devendo o paciente ser periodicamente monitorado, através de exames radiográficos, ate que haja a completa formação do tecido ósseo, já que a recorrência local, apesar de raramente relatada, pode ocorrer.
The sim pie bone cyst is not an ordinary lesion among the oral cavity pathologies and still does not present a conclusive etiology. This can be very well noticed when we face the many terms that have been used to describe it. Clinically speaking, it is not presented in a symptomatic way, being diagnosed, mostly, from X-ray exams. It happens preferably in the teeth regions of the mandible, and can be identified through radiographic exams as an unilocular lesion with no expansion of the surround bone walls. This article aims to relate two clinical cases in which the simple bone cysts have been diagnosed as atypical because of the damage caused on the mandible bone at edentulous regions, considering that in one of them there has been an expansion of the bone walls. Such aspects are not in accordance with what has been described at the common literature. Both clinical cases have been submitted to a curettage proceeding, what developed the bleeding of the bone walls, with subsequent formation of a stable blood coagulum. According to the literature, in most cases, the curettage proceeding at the affected region with the traumatic bone cyst is a very effective therapeutic alternative, in which the patient should be monitored periodically, through radiographic examination, until the bone texture is completely rebuilt, since although it is rare, the local reincidence may occur.