Do oral conditions influence the incidence of bloodstream infection after hematopoietic stem cell transplantation? A retrospective study in Japan.

PURPOSE: This study aimed to evaluate the incidence of bloodstream infection (BSI) among patients undergoing hematopoietic stem cell transplantation (HSCT) for teeth indicated for extraction. METHODS: Patients who underwent HSCT at Toranomon Hospital (Tokyo, Japan) between January 2017 and December 2019 were retrospectively evaluated. The incidence of BSI among patients with teeth indicated for extraction who did not undergo extraction (oral high-risk group) and patients who did not have this risk (oral low-risk group) was compared. RESULTS: Among the 191 consecutive patients included in this study, 119 patients were classified as undergoing high-risk transplantation. BSI after HSCT was observed in 32 out of 60 (53.3%) patients and 56 out of 131 (42.7%) patients in the oral low-risk and oral high-risk groups, respectively (p = 0.173). Multivariable analyses revealed that the presence of > 3 teeth as intraoral sources of infection and age over 50 years were determinants of BSI originating from the oral cavity after engraftment (odds ratio [OR], 9.11; 95% confidential interval [CI] 2.27-36.61]; p = 0.002; OR, 3.22; CI [1.47-7.08], p = 0.004, respectively). CONCLUSION: In patients undergoing HSCT, the presence of less than three intraoral sources of infection did not affect the incidence of BSI after HSCT.

DO ORAL CARE AND REHABILITATION IMPROVE COGNITIVE FUNCTION? A SYSTEMATIC REVIEW OF CLINICAL STUDIES.

OBJECTIVES: An increasing number of studies have identified an association between oral health status and cognitive function. However, the effect of oral interventions, including oral health care, dental treatment and oral motor exercises, on cognitive function remains unclear. This systematic review examined whether oral interventions contribute to the long-term improvement of cognitive status. METHODS: Four databases were searched (MEDLINE, Web of Science, Cochrane Library, and ICHUSHI Web) to identify randomized and nonrandomized controlled trial studies and prospective cohort studies from inception until 1 September 2023, published in English or Japanese. The Cochrane risk of bias tool for randomized controlled trials and the risk of bias assessment tool for nonrandomized studies were used to assess bias risk. RESULTS: A total of 20 articles were included in the qualitative analysis; 13 articles were published in English, and 7 were published in Japanese. The implemented interventions were oral care in 8 studies, dental treatment in 8 studies, and oral motor exercise in 4 studies. One study found a significant effect on attention following oral care intervention. Some dental treatments influenced cognitive function, although a clear positive effect was not determined. In 1 study, attention and working memory improved in the chewing exercise group. CONCLUSIONS: Several studies verified the improvement effects of oral interventions, such as oral care, dental treatment, and oral motor exercise, on cognitive function or impairment. However, there was still a lack of conclusive evidence that such an intervention clearly improved cognitive function. To clarify the effects of oral interventions on cognitive function, it is necessary to examine participants, interventions, and outcome measures in detail.

Quantitative text analysis of the mechanisms of tooth injury: Analysis of accidents in five sports that occurred in 15 years under school control.

BACKGROUND/AIM: Dental trauma may occur in school settings and it can impact patients' quality of life. Analysis of the occurrences of dental trauma is essential in identifying preventive methods. There are numerous reports of such accidents but most are quantitative analyses with limited data. The aim of this study was to extract information on the mechanisms of injuries that leads to prevention by performing a qualitative analysis of the occurrence of dental trauma. MATERIAL AND METHODS: After screening 7684 cases of dental injuries that occured in schools and were reported to the Japan Sports Council between 2005 and 2020, 533 detailed descriptions of injuries that occurred during sports were included. Quantitative text analysis was performed on the target data by performing statistical analysis, extracting frequently used words, and creating a co-occurrence network. Injury mechanisms were evaluated based on appearance of words. RESULTS: Dental injuries occurred frequently in five sports included in the survey. They were in order of decreasing frequency: baseball, basketball, soccer, volleyball, and rugby. Males were injured more often in all sports other than volleyball. The number of accidents increased in all sports among high school students. The frequent word list and co-occurrence network were different for each sport. This allowed typical accident occurrence mechanisms to be extracted for these five sports. CONCLUSIONS: Typical accident occurrence mechanisms were extracted from quantitative text analysis targeting free texts on the occurrence of accidents for five sports. Quantitative text analysis is useful for the evaluation of accident cases, which may aid in accident prevention.

Fracture strength of flared root canals reinforced using different post and core materials.

PURPOSE: To examine the fracture strength and fracture mode of flared root canals reinforced with different post and core materials. MATERIALS AND METHODS: Forty endodontically treated bovine teeth structured to mimic human mandibular premolars with flared root canals were reinforced with resin composite and glass fiber post (FRC), composite resin (RC), ceramic core (LD), and ceramic core with resin composite reinforcement (RLD), and restored with single zirconia crowns (n = 10 in each group). The fracture strength and mode of the root canals restored with zirconia crown were assessed. The fracture strength was compared with a one-way analysis of variance (ANOVA) following Tukey HSD tests. A multiple regression analysis was conducted to test the effect of the post/core materials on the fracture loads. Fisher's exact test was used in the failure mode analysis. RESULTS: The mean fracture strength of RLD was significantly higher than RC, FRC, and LD (p < 0.05), while no significant differences were found among RC, FRC, and LD (p < 0.05). The regression analysis found that the fracture strength using the lithium disilicate was significantly lower for the post and higher for the core than that using the resin composite (p < 0.05), and there were no significant difference in the fracture strengths between the resin composite and glass fiber used for the post (p > 0.05). Most of the specimens exhibited root fractures, and no significant differences were observed among the groups (p < 0.05). CONCLUSIONS: The results of this study suggest that reinforcement of flared root canals using a combination of resin composite for the core and lithium disilicate ceramic for the post is superior to resin composite and glass fiber in mechanical properties when restoring a single crown.

Functional oral health-related quality of life impact: A systematic review in populations with tooth loss.

Patients perceive the impact of oral disorder in four major areas, the dimensions of oral health-related quality life (OHRQoL) Oral Function, Orofacial Pain, Orofacial Appearance, and Psychosocial Impact. The functional aspect is essential given the need of chewing, biting, speech and swallowing. The objective of this study was to identify OHRQoL information for dental subjects with functional oral health problems. In a systematic review, distinct and clinically relevant groups of dental subject samples, in this study called "population groups," with such functional OHRQoL information based on the Oral Health Impact Profile (OHIP) were identified (PROSPERO registration: CRD42017064033). The search strategy was "Oral Health Impact Profile" or OHIP. Searches were conducted in the PubMed interface of the Medline database, EMBASE, Cochrane, CINAHL and PsyINFO on 8 June 2017 and updated on 14 January 2019. Published OHIP domain data of different versions were recalculated into OHIP-14`s Physical Disability domain score, characterising the subject's Oral Function impact. 3,653 potentially abstracts were screened. We identified 78 publications reporting dimensional information on 154 subject samples with 52 populations. A typical mean functional impact for partially dentate subjects was 1.6 units on a 0 to 8 unit metric, while for edentate subjects, the mean functional impact was 2.6 units. The functional impact score ranged from 0 to 7.9 units with 50% of the patient samples located between 0.8 and 2.6 units. For the first time, we provide normalised and therefore comparable metric information about the functional OHRQoL impact for a substantial number of functional oral conditions.

A new masticatory performance scale to integrate food biting, comminution and mixing ability in removable partial denture wearers.

BACKGROUND: The existing masticatory performance (MP) tests cannot comprehensively evaluate objective masticatory function. OBJECTIVES: We aimed to examine the construct validity and responsiveness and determine the clinically minimum important difference (MID) and related factors of a newly developed MP scale to integrate food biting, comminution and mixing ability in patients with removable partial dentures (RPDs). METHODS: Masticatory performance tests using gummy jelly, peanuts and colour-changeable gum were performed before and 3 months after RPD treatment in 248 partially dentate patients. A 10-point ordinal subscale was created for each MP test based on the distributions of MP values, and the three subscales were integrated into a single scale (iMP scale). We analysed the correlations between MP values and iMP scores and determined the effect size for RPD treatments and the MID on the basis of patient perception of chewing ability. RESULTS: iMP scores exhibited moderate correlations with the three MP values (|ρ| = 0.73-0.79, p < .001) and with the change scores (|ρ| =0.61-0.64, p < .001). The mean iMP score significantly increased after RPD treatment (p < .001), and the effect size was 0.35. Of the 248 patients, 55 (22%) reported a slight improvement in chewing ability with a mean iMP score change of 2.1 points. Sex and the number of missing teeth were significantly associated with iMP scores (p < .05). CONCLUSIONS: The iMP scale comprehensively evaluated objective masticatory function, including food biting, comminution and mixing ability in RPD wearers, and an increase of two points on the iMP scale was considered to be the MID in RPD treatments.

Responsiveness of methods to evaluate chewing ability after removable partial denture treatments.

BACKGROUND: The ability of an instrument to detect a clinically important change in patient-reported outcomes following prosthetic treatment is critical for its use in clinical practice and research settings. OBJECTIVES: This study aimed to examine the responsiveness of instruments in evaluating patient perception of chewing ability after removable partial denture (RPD) treatment in a prospective cohort. METHODS: A single 100-mm visual analogue scale (VAS), 20-item food intake questionnaire (FIQ) and 6-point chewing difficulty scale (CDS) were administered to 248 partially edentulous patients to evaluate chewing ability pre- and post-RPD treatment. We conducted a statistical comparison between the pre- and post-treatment scores and determined the effect size (r) of RPD treatment for the instruments. RESULTS: A significant improvement in chewing ability after RPD treatment was identified by VAS and CDS (P < .05), but not by FIQ (P = .16), which identified an improvement after controlling for sex, age, the number of missing teeth and presence/absence of existing removable dentures. The effect size was medium for VAS (r = .54), weak for CDS (r = .14-.17) and absent for FIQ (r = -.09). The increase in r was significantly associated with impaired chewing ability before treatment (ρ = -0.87, P < .001). CONCLUSIONS: These results suggest that the 100-mm VAS, followed by CDS, is the most responsive instrument to detect an improvement in chewing ability after RPD treatment. Pre-treatment impairment of chewing ability was associated with better responsiveness of the instruments.

Mapping Oral Disease Impact with a Common Metric (MOM)-Project summary and recommendations.

Oral Function, Orofacial Pain, Orofacial Appearance, and Psychosocial Impact-the dimensions of oral health-related quality of life-capture dental patients' oral health problems worldwide and regardless of whether the patient currently suffers from oral diseases or intends to prevent them in the future. Using scores for these dimensions, the project Mapping Oral Disease Impact with a Common Metric (MOM) aims to provide four-dimensional oral health impact information across oral diseases and settings. In this article, project authors summarize MOM's findings and provide recommendations about how to improve standardized oral health impact assessment. Project MOM's systematic reviews identified four-dimensional impact information for 189 adult and 22 pediatric patient populations that were contained in 170 publications. A typical functional, pain-related, aesthetical, and psychosocial impact (on a 0-8 impact metric based on two items with a response format 0 = never, 1 = hardly ever, 2 = occasionally, 3 = fairly often, 4 = very often) was about 2 to 3 units. Project MOM provides five recommendations to improve standardized oral health impact assessment for all oral diseases in all settings.

Does oral dryness influence pressure pain sensitivity in the oral mucosa of removable denture wearers?

OBJECTIVE: This study aimed to determine if oral dryness is associated with oral pain sensitivity in removable denture wearers. MATERIALS AND METHODS: The pressure pain threshold (PPT) in the mucosa at the midline between the central incisors in the maxilla and mandible was evaluated in 333 removable denture wearers (mean age 71.2 years, male 33.3%). The frequency of oral dryness and severity of anxiety were evaluated using self-reported questionnaires. Multilevel analyses considering the correlated data structure (jaws nested within individual) adjusted for age, sex, number of missing teeth, anxiety level, smoking status, and systemic diseases were performed to examine the association between PPT and oral dryness. Further subgroup analysis stratified by number of missing teeth was performed. RESULTS: Oral dryness was present in 122 (21.6%) of 566 jaws in 73 (21.9%) of the 333 subjects. The mean (standard deviation) of the log PPT was 2.00 (0.26) in the subjects who perceived oral dryness and 2.04 (0.22) in those who did not. Oral dryness was associated with a lower log PPT, but the relationship was not significant (coefficient - 0.017; 95% confidence interval - 0.071, 0.038). Subjects with oral dryness and edentulous oral mucosa had a significantly lower PPT (coefficient - 0.145; 95% confidence interval - 0.283, - 0.006) than their partially dentate counterparts. CONCLUSION: There was a significant association of oral dryness with increased pressure pain sensitivity in the oral mucosa only in jaws with complete dentures. CLINICAL RELEVANCE: The approach to oral dryness could contribute to reduction of oral pain sensitivity.

Pre-treatment impairment of oral health-related quality of life is associated with variations in minimal clinically important differences among patients with removable partial denture treatment.

BACKGROUND: The minimal clinically important differences (MID) of the Oral Health-related Quality of Life (OHRQoL) are the benchmark to meaningfully interpret treatment outcomes. However, there is no available information regarding the factors impact the MID variations after removable partial denture (RPD) treatment. OBJECTIVE: The purpose of this study was to determine the influence of the pre-treatment OHRQoL impairment on the MID in the oral health impact profile (OHIP) after RPD treatment. METHODS: In this prospective study, OHIP and Self-reported Oral Health (SROH) questionnaires were administered to patients before and 3 months after RPD treatment. The MID in each OHIP version (OHIP-49, OHIP-20, OHIP-14 and OHIP-5) was the mean score of patients who showed a minimum SROH improvement. Multiple linear regression analysis was conducted to determine the influence of the pre-treatment OHIP summary score on the MID score. RESULTS: Among 248 participants who completed both evaluations, 85 (34%) patients had minimum SROH improvements after RPD treatment. Multiple regression analysis indicated that each 10-point increase in the pre-treatment summary OHIP score was associated with an increase in the MID score of three points for OHIP-49 and four points for OHIP-20, OHIP-14 and OHIP-5 (P < .05), after controlling for age, sex and the number of missing teeth. Therefore, the MID increased as the pre-treatment OHRQoL was impaired. CONCLUSIONS: The MID was accounted for by approximately one-third of the pre-treatment summary score, independent of the OHIP version, in the interpretation of the effects of RPD treatment on patients' OHRQoL.

The association between mucosal pain and subjective masticatory function in patients with partial removable dental prostheses.

BACKGROUND: Improvement of masticatory function is critical in prosthetic treatment. Multiple factors are related to patients' perception of chewing ability in denture wearers. However, the associations between such factors and chewing ability have not yet been fully elucidated. OBJECTIVE: To investigate the association between mucosal pain and subjective masticatory function in patients with partial removable dental prostheses (PRDPs). METHODS: This cross-sectional study included 333 consecutive patients with PRDPs (mean age 71.2 years, male 33.3%) who were recruited from the prosthetic clinic of a dental hospital in Japan. Patients' perception of chewing ability was evaluated using a food intake questionnaire consisting of 20 items, and chewing difficulty was rated by patients using an 11-point numerical scale. Participants rated the pain intensity of the denture-supporting mucosa and oral dryness while chewing. In addition, the bilateral maximal biting force (MBF) was recorded. A structural equation model was used to identify the factors associated with chewing ability and chewing difficulty. RESULTS: The model indicated that mucosal pain, oral dryness, the number of occluding pairs, the denture type (interim/definitive PRDPs) and the MBF were significant independent predictors of chewing ability and chewing difficulty (P < 0.01). CONCLUSIONS: Our findings suggest that mucosal pain is a risk factor for impairment of subjective masticatory function in patients with PRDPs. It is clinically important to consider the denture design and to select denture base materials with regard to the prevention of mucosal pain.

A comparison of the fitting accuracy of thermoplastic denture base resins used in non-metal clasp dentures to a conventional heat-cured acrylic resin.

OBJECTIVE: To incorporate a metal framework into removable partial dentures, the dimensional accuracy of thermoplastic resins requires precision equivalent to conventional acrylic resins. This study aimed to evaluate the fitting accuracy of thermoplastic resins compared to heat-cured acrylic resin. MATERIALS AND METHODS: Four thermoplastic resins (polyethylene terephthalate [EstheShot, ES; EstheShot Bright, ES-B], polyamide [Lucitone FRS, LF], polycarbonate [Reigning Resin N, RN] and a heat-curing acrylic resin [Acron, AC]) were used. The specimens were created on master casts constructed of high-strength stone that simulated a maxillary edentulous ridge. Additionally, high-expansion stone was used as the master cast for RN specimens. The ES-B, LF and RN specimens were prepared with and without annealing after injection molding. The gaps between the molded resin and the cast were measured. RESULTS: ES had the smallest gap and was significantly smaller than AC (p < 0.05). The gap sizes of ES-B, LF and RN (high-expansion stone) without annealing were similar to AC (p > 0.05), while the gap size of RN (high-strength stone) with and without annealing was significantly greater than AC (p < 0.001). The gap sizes of ES-B and LF with annealing were significantly less than AC (p < 0.05). Further, the gap sizes of ES-B, LF and RN with annealing were significantly smaller than the gaps without annealing (p < 0.05). CONCLUSIONS: The results suggested that ES, ES-B and LF have adequate fitting accuracy for incorporating metal framework into dentures and that annealing effectively improved the fitting accuracy of ES-B, LF and RN.

Clinical application of robots in dentistry: A scoping review.

PURPOSE: The surge in digitalization and artificial intelligence has led to the wide application of robots in various fields, but their application in dentistry started relatively late. This scoping review aimed to comprehensively explore and map the current status of the clinical application of robots in dentistry. STUDY SELECTION: An iterative approach was used to gather as much evidence as possible from four online databases, including PubMed, the China National Knowledge Infrastructure, the Japan Science and Technology Information Aggregator, Electronic, and the Institute of Electrical and Electronics Engineers, from January 1980 to December 2022. RESULTS: A total of 113 eligible articles were selected from the search results, and it was found that most of the robots were developed and applied in the United States (n = 56; 50%). Robots were clinically applied in oral and maxillofacial surgery, oral implantology, prosthodontics, orthodontics, endodontics, and oral medicine. The development of robots in oral and maxillofacial surgery and oral implantology is relatively fast and comprehensive. About 51% (n = 58) of the systems had reached clinical application, while 49% (n = 55) were at the pre-clinical stage. Most of these are hard robots (90%; n = 103), and their invention and development were mainly focused on university research groups with long research periods and diverse components. CONCLUSIONS: There are still limitations and gaps between research and application in dental robots. While robotics is threatening to replace clinical decision-making, combining it with dentistry to gain maximum benefit remains a challenge for the future.

Surface strain at the cervical area and fracture strength of flared root canals reinforced using a zirconia tube and glass-fiber post.

Background/purpose: Recently, an effective core build-up system for teeth with flared root canals is needed. This research aimed to evaluate the effect of foundation restorations using a composite resin core with a fiber post reinforced with a zirconia tube for the surface strain at the cervical area and the fracture load of teeth with flared root canals. Materials and methods: Bovine teeth were shaped to mimic human premolars with flared root canals and restored using three types of composite resin foundation restorations with each materials described below: a fiber post (FC), a zirconia tube (ZC), a fiber post and zirconia tube (ZFC). Each specimen was restored with a zirconia crown. The surface strains of the specimens at the cervical area and fracture loads were analyzed using a one-way analysis of variance (ANOVA), followed by Tukey's honest significant difference test. Results: The surface strains of Groups ZFC and ZC were significantly lower than that of Group FC in the buccal root. The fracture strengths of Groups ZFC and ZC were significantly higher than that of Group FC. The strength of Group ZFC was significantly higher than that of Group ZC. Conclusion: The use of a composite resin core with a zirconia tube for the simulated premolar with flared root canals reduced surface strain at the cervical area and provided higher fracture strength compared to using a composite resin core with a fiber post. And the zirconia tubes provided even higher fracture strength when used with a fiber post.

Effects of immersion in 4-methacryloyloxyethyl trimellitate anhydride/methyl methacrylate-tri-n-butyl borane resin-activated liquid on microtensile bond strength of root canal dentin.

Background/purpose: 4-methacryloyloxyethyl trimellitate anhydride/methyl methacrylate-tri-n-butyl borane (4-META/MMA-TBB) resin is used for indirect restorations. We aimed to evaluate effects of immersion in 4-META/MMA-TBB-activated liquid on the bond strength of root canal dentin. Materials and methods: We used freshly extracted single-rooted human teeth. After decoronation, each root was vertically sectioned into halves; their dentin walls were polished and flattened. The control group underwent dentin treatment with Green Activator. The immersion group was treated with Green Activator and Teeth Primer and immersed in 4-META/MMA-TBB-activated liquid. After bonding the resin blocks with Super-Bond, microtensile bond strength (µTBS) tests were performed (n = 6), and fracture surfaces were analyzed. Before surface treatment, dentin was immersed in a sodium fluorescein solution for 3 h, and resin blocks were bonded with Super-Bond with rhodamine B as in the bond strength test. The bonded cross section was observed using confocal laser scanning microscopy (CLSM). Results: µTBS was significantly higher in the immersion group than in the control group (61.5 [51.3-66.7] vs. 33.0 [20.4-57.8] MPa; P < 0.05). Fracture mode analysis showed that, compared with the control group, the immersion group had a significantly lower rate of adhesive failure at the dentin interface and a significantly higher rate of cohesive failure in Super-Bond (P < 0.01). CLSM showed a water droplet-like accumulation of fluorescein dye above the hybrid layer in the control group, not in the immersion group. Conclusion: Immersion in a 4-META/MMA-TBB-activated liquid inhibited water exudation from the root canal dentin and improved the bond strength.

Marginal fit and retention force of zirconia resin-bonded fixed dental prostheses in the posterior region with different designs.

Background/purpose: Retainer debonding of resin-bonded fixed dental prostheses (RBFDPs) is one of the major reasons for their lower survival rates than fixed dental prostheses (FDPs) with full-coverage crowns. Recent advances in milling technology have enabled the fabrication of RBFDPs with complex retainers (D-shaped designs). This study aimed to assess the marginal fit and retention force of zirconia RBFDPs with inlay-, L-, and D-shaped designs to clarify their clinical applications. Materials and methods: Three abutment teeth models without maxillary second premolars were created using inlay-, L-, and D-shaped retainer designs. The zirconia RBFDPs were designed and fabricated according to the manufacturer's instructions (n = 10). The marginal gap was measured using the silicone replica technique. Zirconia frameworks were bonded to the abutment teeth using resin cement. Tensile test was conducted after thermal cycling and dynamic loading tests. The loads during debonding or fracture were recorded. The failure pattern was analyzed by observing the fracture surface using a scanning electron microscope. Results: D-shaped RBFDPs showed a significantly larger marginal gap than inlay- and L-shaped RBFDPs (P < 0.05). However, the mean marginal values were clinically acceptable (<120 µm). The D-shaped model exhibited the highest tensile strength in the tensile tests. The inlay-shaped and most of the D-shaped RBFDPs experienced debonding with cohesive failure, whereas the L-shaped RBFDPs showed fractures near the connector. Conclusion: The D-shaped retainer design was superior to the inlay- and L-shaped designs with respect to the inhibition of retainer debonding. However, the marginal fitness needs to be improved.

Emergence angle: Comprehensive analysis and machine learning prediction for clinical application.

PURPOSE: To analyze and compare the emergence angle (EA) using two measurement methods, conventional and modified (EA-GPT and EA-R), the EAs of all-natural teeth were evaluated and classified to derive a suitable and predictable clinically applicable measurement method. METHODS: Natural human teeth (n=600) were classified, cleaned, and thoroughly inspected. Teeth were scanned using an intraoral scanner. The scanned data were analyzed using three-dimensional analysis software for both methods with several points per surface. A Bland-Altman analysis was used for statistical analysis and a heat map and a nonparametric density plot to assess the repetition and distribution. An XGBoost regression model was used for prediction. RESULTS: The EA-R method showed significantly different values compared to the EA-GPT method, representing an increase of 17.5-20.7% for the proximal surfaces. An insignificant difference between the two methods was observed for other surfaces. Different teeth classes showed variation in the normal range, thereby resulting in a new classification of the EA for all-natural teeth based on the interquartile range. The machine learning gradient boosting model predicted conventional data with an average mean absolute error of 0.9. CONCLUSIONS: Variations in the natural teeth EA and measurement methods, suggest a new classification for EA. The established artificial intelligence method demonstrated robust performance, which could aid in implementing EA measurement in prosthetic designs.

Knowledge acquisition efficacy of a remote flipped classroom on learning about removable partial dentures.

PURPOSE: Coronavirus disease 2019 has forced the use of remote education worldwide. In 2020, the authors conducted a fully digitized, remote flipped (RF) classroom focusing on removable partial dentures. This study aimed to evaluate the learning outcomes of the RF classroom and compare these with those of the on-site classroom. METHODS: The fourth-year dental students in 2017-2019 attended on-site flipped classroom (OF; n=70) or on-site lecture classroom (OL; n=67), and those in 2020 (n=58) attended the RF classroom. Lecture videos and text were provided online in the OF and RF groups, while only the text was given to the OL group. Individual and group tests were conducted to assess knowledge acquisition one week after all the classes ended. A one-way analysis of variance following Tukey's test was performed to compare individual/group test scores among the OF, OL, and RF groups. Multilevel linear regression analysis was performed to identify the factors associated with an increase in each test score. RESULTS: The mean individual test scores in the RF and OF groups were significantly higher than in the OL group (P<0.01). The mean group test score in the RF group was significantly higher than in the OF and OL groups (P<0.001). The multilevel analysis identified remote and flipped classroom styles in the individual test, and the remote style in the group test, as significant effective factors in learning (P<0.05). CONCLUSIONS: These results suggest that the RF classroom is more effective than the on-site lecture in knowledge acquisition in undergraduate prosthodontic education.

A composite resin core with a new zirconia tube reduces the surface strain at the cervical area of a mandibular molar: A model tooth study.

PURPOSE: This study aimed to evaluate the surface strain at the cervical area of endodontically treated molars with a large pulp chamber restored using a composite resin core with three different types of core build-up systems. METHODS: Reproduction models of human mandibular molars with prepared post spaces were used in this study. Roots duplicated with a composite resin were used as the experimental teeth. Three types of core build-up systems were used: composite resin core(RC), composite resin core with fiber posts (FC), and composite resin core with a prefabricated zirconia tube (ZC). Each group comprised eight specimens. Crowns made of yttria partially stabilized zirconia were cemented with dual-cure resin cement. Four strain gauges were attached to the surfaces of each specimen: the cervical area of the root and crown, on the buccal and lingual sides. The surface strain at each cervical area was measured using a static loading test and statistically analyzed. RESULTS: In the case of static loading to the buccal cusp inner slope, ZC showed a significantly lower strain than RC in the crown on the buccal side and in the root and FC in the root. In the central fossa, ZC showed a significantly lower strain than FC in the root on the lingual side. CONCLUSIONS: The prefabricated zirconia tube reduced the surface strain at the cervical area of the buccal/lingual root in molars; however, the effect was small in the cervical area of the crown.

Effects of delayed-onset muscle soreness on masticatory function.

The aim was to clarify the effects of experimentally provoked delayed-onset muscle soreness (DOMS) in the jaw-closing muscles on subjective and objective measures of masticatory function. Twenty-one dentate female subjects, without pain-related signs and symptoms of temporomandibular disorders, participated. Delayed-onset muscle soreness was provoked with eccentric and concentric contractions of the jaw-closing muscles using a custom-made apparatus. At baseline, and 24 h and 1 wk after the exercises, data were gathered on the subjective measures of muscle fatigue, muscle pain, and masticatory chewing ability using visual analogue scale (VAS) scores, on the maximum voluntary bite force (MVBF), and on the food Mixing Ability Index (MAI). After 24 h, muscle fatigue and muscle pain had increased and the MAI had decreased. All had returned to baseline levels after 1 wk. There were no significant changes found in the chewing ability VAS scores and in the MVBF over time. After correction for its baseline value, the MAI after 24 h was found to be significantly related to the muscle pain after 24 h. In conclusion, DOMS in the jaw-closing muscles can cause a decrease in the objectively scored chewing ability, while the subjectively scored chewing ability remained the same.