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1.
Oral Maxillofac Surg ; 27(1): 69-78, 2023 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-35119553

RESUMO

The aim of this cohort case series is to present a new subperiosteal implant device that uses CAD-CAM technologies together with 3D metal printing capabilities to produce direct bone-anchored dental prosthetic solutions for the management of atrophic edentulous alveolus and jaws. The clinical experience of 21 subperiosteal devices implanted over a 4-year period is presented. The results of this study showed 14 of the 21 cases were successful (66.7%), while 7 cases had complications including exposure of the metal frame (5 cases), mobility of the device (1 case) and 1 case failed for reasons unrelated to the device. Four of the 7 cases were successfully salvaged resulting in an overall success rate of 85.7% (18 /21 cases). This study supports the use of fully customized subperiosteal jaw implants as a simple and reliable alternative for dental rehabilitation of atrophic edentulous cases which would otherwise require bone grafts for conventional fixed dental implant solutions. With more research, the clinical potential for this device is significant as it not only avoids the need for complex and lengthy reconstructive jaw surgery but also allows for the placement of immediate prosthetic teeth at the time of implantation.


Assuntos
Implantes Dentários , Arcada Edêntula , Boca Edêntula , Humanos , Arcada Edêntula/reabilitação , Arcada Edêntula/cirurgia , Boca Edêntula/cirurgia , Maxila/cirurgia , Prótese Dentária Fixada por Implante , Implantação Dentária Endóssea/métodos , Resultado do Tratamento , Seguimentos , Falha de Restauração Dentária
2.
J Craniomaxillofac Surg ; 43(7): 1127-32, 2015 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-26032758

RESUMO

PURPOSE: To describe the efficacy of denosumab in the treatment of an aggressive giant cell granuloma of the mandible. METHODS: Denosumab was administered to a patient with a large aggressive giant cell granuloma of the mandible resistant to standard medical therapy. The effectiveness and response was measured on the basis of patient symptoms and radiological parameters. RESULTS: A significant reduction in patient symptoms was reported in association with tumour regression on follow up radiographs. CONCLUSION: This report demonstrates potential use of denosumab in aggressive giant cell granulomas of the jaws that have been resistant to medical therapy.


Assuntos
Conservadores da Densidade Óssea/uso terapêutico , Denosumab/uso terapêutico , Granuloma de Células Gigantes/tratamento farmacológico , Adulto , Conservadores da Densidade Óssea/administração & dosagem , Denosumab/administração & dosagem , Feminino , Humanos
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