Nickel sulfide nanoworm network architecture as a binder-free high-performance non-enzymatic glucose sensor.

Nickel sulfide nanoworm (Ni3S2 NW) network architecture was directly grown on the poly (3,4-ethylenedioxythiophene)-reduced graphene oxide hybrid films (PEDOT-rGO HFs) modified on glassy carbon electrode (GCE), acting as a binder-free sensor for high-performance non-enzymatic glucose monitoring. The sensor exhibited the satisfactory sensitivity (2123 µA mM-1 cm-2), wide linear range (15~9105 µM), low detection limit (0.48 µM), and rapid response time (< 1.5 s) at a potential of 0.5 V (vs. SCE) in 0.1 M NaOH and possessed good selectivity, reproducibility, and stability. The enhanced electrocatalytic activity of the sensor towards glucose oxidation was attributed to the particular morphology, satisfying hydrophilic nature, strong combination between Ni3S2 NWs, PEDOT-rGO, and bare GCE. Moreover, it can be used for assaying glucose in human serum samples without dilution, indicating potential for clinical diagnostic applications. Graphical abstract Nickel sulfide nanoworms (Ni3S2 NWs)/poly (3,4-ethylenedioxythiophene)-reduced graphene oxide hybrid films (PEDOT-rGO HFs) were used to construct a binder-free high-performance non-enzymatic glucose sensor with satisfactory sensitivity, wide linear range, low detection limit, good selectivity, amazing reproducibility, and stability.

Curly fish scales-like Ni2.5Mo6S6.7 electrodeposited on PEDOT-rGO with uneven surface as ultrafast response electrode for electrocatalytic glucose, nitrite and hydrogen peroxide.

The difficulty to achieve rapid detection is the limitation of many enzyme-free sensors today. Thus, designing tri-functionalsensors with ultra-fast and efficientdeterminationis a challenging taskin biological science. Herein, curly fish scales-like Ni2.5Mo6S6.7 active materials was anchored on poly (3,4-ethylenedioxythiophene)-reduced graphene oxide (PEDOT-rGO) hybrid membranes with uneven surface (Ni2.5Mo6S6.7/PEDOT-rGO) as a high-performance tri-functional catalyst for glucose, nitrite and hydrogen peroxide determination.The sensor constructed under optimal conditions exhibited ultrafast response performance towards glucose and nitrite within 2 s, and hydrogen peroxide within 1 s. Meanwhile, it provided the wide linear range with a low detection limit towards glucose (as low as 0.001 mM and up to 15.000 mM, and 0.33 µM), nitrite (as low as 0.001 mM and up to 10.000 mM, and 0.33 µM) and hydrogen peroxide (from 0.010 mM to 7.000 mM, and 0.79 µM), respectively. In addition, the sensor demonstrated satisfied selectivity, repeatability, reproducibility and stability. Furthermore, the sensor has potential application in real samples. This study may provide a new strategy for the construction of tri-functional electrode materials with the ultra-fast response.