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1.
Food Chem ; 435: 137534, 2024 Mar 01.
Artigo em Inglês | MEDLINE | ID: mdl-37769562

RESUMO

The insufficient water vapor barrier and mechanical capacity of sodium alginate (SA) film limited its application in fruit preservation. Herein, cellulose nanocrystals (CNCs) were used to stabilize Pickering emulsion. Then, we prepared SA composite films. Ginger essential oil (GEO) was loaded as antimicrobials and antioxidants. Finally, the application on mangos were investigated. Compared to coarse emulsion, Pickering emulsion and its film-formation-solution showed more stable system and larger droplet size. The emulsion significantly changed the properties of SA film. Specifically, CNCs improved the thermal, tensile, and barrier properties of the film and GEO enhanced the ultraviolet-visible light barrier capacity. Additionally, the SA/CNC film possessed a homogeneous micromorphology which had a sustained-release effect on GEO, thus maintaining high postharvest quality and long-term bioavailability for mangos. In conclusion, the film prepared via Pickering emulsion showed satisfactory properties which had great potential in fruit preservation.


Assuntos
Mangifera , Nanopartículas , Óleos Voláteis , Zingiber officinale , Emulsões/química , Alginatos/química , Preparações de Ação Retardada , Frutas , Celulose/química , Nanopartículas/química
2.
ACS Nano ; 18(21): 13528-13537, 2024 May 28.
Artigo em Inglês | MEDLINE | ID: mdl-38747549

RESUMO

Dental caries is a widespread oral disease that poses a significant medical challenge. Traditional caries prevention methods, primarily the application of fluoride, often fall short in effectively destroying biofilms and preventing enamel demineralization, thereby providing limited efficacy in halting the progression of caries over time. To address this issue, we have developed a green and cost-effective synergistic strategy for the prevention of dental caries. By combining natural sodium phytate and chitosan, we have created chitosan-sodium phytate nanoparticles that offer both the antimicrobial properties of chitosan and the enamel demineralization-inhibiting capabilities of sodium phytate. In an ex vivo biofilm model of human teeth, we found that these nanoparticles effectively prevent biofilm buildup and acid damage to the mineralized tissue. Additionally, topical treatment of dental caries in rodent models has shown that these nanoparticles effectively suppress disease progression without negatively impacting oral microbiota diversity or causing harm to the gingival-mucosal tissues, unlike traditional prevention methods.


Assuntos
Biofilmes , Quitosana , Cárie Dentária , Nanopartículas , Ácido Fítico , Cárie Dentária/prevenção & controle , Quitosana/química , Quitosana/farmacologia , Humanos , Nanopartículas/química , Ácido Fítico/química , Ácido Fítico/farmacologia , Ácido Fítico/administração & dosagem , Animais , Biofilmes/efeitos dos fármacos , Streptococcus mutans/efeitos dos fármacos , Antibacterianos/farmacologia , Antibacterianos/química , Antibacterianos/administração & dosagem , Camundongos
3.
Int J Biol Macromol ; 166: 288-296, 2021 Jan 01.
Artigo em Inglês | MEDLINE | ID: mdl-33129905

RESUMO

Due to the environmental pollution problems caused by plastic-based packaging, the development of edible food packaging films is imminent. However, the performance of most edible packaging films is insufficient to meet practical applications, so recent studies have focused on the research of various fillers to improve film properties. This article reviews recent applications of cellulose nanocrystals (CNC) and cellulose nanofiber (CNF) in edible food packaging films including the effect on thickness, optical properties, barrier properties, water sensitivity, mechanical properties, antioxidant and antimicrobial properties. The main conclusion of this review is that the incorporation of CNC and CNF could significantly improve the performance of edible food packaging films. Particular finding is that although CNC and CNF can be used as excellent addition to improve the performance of edible food packaging films, there is a key "optimum" concentration. In addition, we also found that CNC and CNF as excellent controlled release agents and stabilizers significantly increased the antioxidant and antibacterial properties of edible food packaging films.


Assuntos
Celulose/química , Filmes Comestíveis/normas , Nanofibras/química , Nanopartículas/química
4.
Int J Nanomedicine ; 15: 9389-9405, 2020.
Artigo em Inglês | MEDLINE | ID: mdl-33262594

RESUMO

INTRODUCTION: Polyimide (PI) exhibits good biocompatibility and high mechanical strength, but biological inertness that does not stimulate bone regeneration, while laponite possesses excellent bioactivity. METHODS: In this study, to improve the bioactivity of PI, nano-laponite ceramic (LC)-PI composites (LPCs) were fabricated by melt processing as implantable materials for bone repair. RESULTS: The compressive strength, hydrophilicity, and surface roughness of LPCs with 40 w% LC content (LPC40s) were higher than LPC20s, and LPC20s higher than pure PI. In addition, no apatite mineralization occurred on PI, while apatite mineralized on LPCs in simulated body fluid. Compared with LPC20, more apatite deposited on LPC40, indicating good bioactivity. Moreover, the adhesion, proliferation, and alkaline phosphatase activity of rat bone mesenchymal stem cells on LPCs significantly increased with LC content increasing in vitro. Furthermore, the evaluations of animal experiments (micro-CT, histology, and pushout load) revealed that compared with LPC20 and PI, LPC40 significantly enhanced osteogenesis and osseointegration in vivo. DISCUSSION: Incorporation of LC into PI obviously improved not only surface physicochemical properties but also biological properties of LPCs. LPC40 with high LC content displayed good biocompatibility and bioactivity, which markedly promoted osteogenesis and osseointegration. Therefore, with its superior biocompatibility and bioactivity, LPC40 could be an alternative candidate as an implant for orthopedic applications.


Assuntos
Apatitas/metabolismo , Materiais Biocompatíveis/farmacologia , Cerâmica/química , Imidas/química , Osseointegração/efeitos dos fármacos , Silicatos/química , Silicatos/farmacologia , Animais , Materiais Biocompatíveis/química , Regeneração Óssea/efeitos dos fármacos , Adesão Celular/efeitos dos fármacos , Proliferação de Células/efeitos dos fármacos , Células-Tronco Mesenquimais/citologia , Células-Tronco Mesenquimais/efeitos dos fármacos , Nanoestruturas/química , Osteogênese/efeitos dos fármacos , Ratos , Propriedades de Superfície
5.
Food Chem ; 300: 125194, 2019 Dec 01.
Artigo em Inglês | MEDLINE | ID: mdl-31325749

RESUMO

The effects of near freezing temperature (NFT) storage at -1.9 °C on cell wall degradation of 'Shushanggan' apricot was studied comparing to 0 °C and 5 °C storage. Our results indicated that NFT storage strongly inhibited the solubilization of Na2CO3-soluble pectin and cellulose, by the suppression of cell wall modifying enzymes (polygalacturonase, ß-Galactosidase, pectin methyl esterase and cellulase) and related genes expressions. The loss of side chains was the main modification in CDTA (Cyclohexane-diamine-tetraacetic Acid)-soluble pectin during storage and made the main contribution to the softening of apricot, while the loss of side chain was suppressed by NFT storage. Microscopic observation showed that NFT storage delayed the degradation of pectin fraction and protected cell wall structure from loosing. This study proves that NFT storage is an effective technology to suppress the cell wall polysaccharides degradation and ultrastructure modification of apricot.


Assuntos
Parede Celular/ultraestrutura , Armazenamento de Alimentos/métodos , Polissacarídeos/química , Prunus armeniaca/química , Hidrolases de Éster Carboxílico/química , Hidrolases de Éster Carboxílico/metabolismo , Parede Celular/química , Parede Celular/metabolismo , Celulose/química , Temperatura Baixa , Congelamento , Frutas/química , Frutas/citologia , Frutas/ultraestrutura , Pectinas/química , Células Vegetais/química , Células Vegetais/ultraestrutura , Poligalacturonase/química , Poligalacturonase/metabolismo , Polissacarídeos/metabolismo , Prunus armeniaca/citologia , Solubilidade , beta-Galactosidase/química , beta-Galactosidase/metabolismo
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