Integrated Preparation of Hollow Lignin Nanoparticles as a Drug Carrier and Levulinic Acid from the Poplar Wood Prehydrolysis Liquor.

Prehydrolysis liquid (PHL) from dissolving pulp and biorefinery industries is rich in saccharides and lignin, being considered as a potential source of value-added materials and platform molecules. This study proposed an environmentally friendly and simple method to prepare morphologically controllable hollow lignin nanoparticles (LNPs) and levulinic acid (LA) from PHL. In the first step, after hydrothermal treatment of PHL with p-toluenesulfonic acid (p-TsOH), lignin with a uniform molecular weight was obtained to prepare LNPs. The prepared LNPs have an obvious hollow structure, with an average size of 490-660 nm, and exhibit good stability during 30 days of storage. When the as-obtained LNPs were used as a sustained-release agent for amikacin sulfate, the encapsulation efficiency reached over 70% and the release efficiency within 40 h reached 69.2% in a pH 5.5 buffer. Subsequently, the remaining PHL that contains saccharides was directly used for LA production under the catalysis of p-TsOH. At 150 °C for 1.5 h, the LA yield reached 58.4% and remained at 56% after 5 cycles of p-TsOH. It is worth noting that only p-TsOH was used as a reactive reagent throughout the entire preparation process. Overall, this study provided a novel pathway for the integrated utilization of PHL and showed the immense potential of the preparation and application of LNPs.

Integrated preparation of functional lignin nanoparticles and levulinic acid directly from the pre-hydrolysis liquor of poplar wood.

The pre-hydrolysis liquor (PHL) produced during pulp dissolution and biomass refining is mainly composed of hemicellulose and lignin, and it is a potential source for production of value-added materials and platform chemicals; however, their utilization has been a serious challenge. In this study, we proposed a green and simple strategy to simultaneously prepare size-controlled functional lignin nanoparticles (LNPs) and levulinic acid (LA) from PHL as the raw material. The as-prepared LNPs exhibited remarkable stability thanks to the presence of saccharides with abundant oxygen-containing groups and surface charges, which prevented aggregation and maintained long-term storage stability. Trace amounts of the LNPs (≤ 0.2 wt%) could stabilize various Pickering emulsions, even with oil-to-water ratios as high as 5:5 (v/v). Subsequently, the remaining PHL was directly used to produce LA without adding a catalyst; under optimal conditions (160 °C and 1 h), the yield of LA was 56.3 % based on the dry saccharide content in the raw PHL. More importantly, p-toluenesulfonic acid (p-TsOH), the only reactive reagent used during the entire preparation process, including the two preparation steps of the LNPs and LA, was reusable, and the recovery rate was >70 % after five cycles. Overall, this green and simple strategy effectively and comprehensively utilized the PHL and showed potential for producing biobased nanomaterials and platform chemicals.

Advances in green materials derived from wood for detecting and removing mercury ions in water.

The issue of mercury pollution in environmental remediation has garnered significant attention due to its severe health hazards to humans. Various strategies have been devised to mitigate the impact of toxic mercury ions, including coagulation, ion exchange, adsorption, membrane technology, and electrochemical treatment. Among these approaches, adsorption has emerged as an efficient and widely employed method for the uptake of low concentrations of mercury ions. It offers convenient operation, high removal efficiency, and facile regeneration of the adsorbent. Wood, being the most abundant renewable and sustainable bioresource, has garnered attention as a promising material for treating heavy metal wastewater. This is attributed to its unique physical and chemical characteristics, encompassing hierarchical pores, aligned channels, active functional groups, biodegradability, and cost-effectiveness. However, a comprehensive examination of the cutting-edge applications of wood and wood-derived biopolymers in the detection and removal of mercury ions from wastewater has yet to be undertaken. Consequently, this article presents a chronological overview of recent advancements in materials and structures derived from bulk wood and its constituents, including cellulose, lignin, hemicellulose, and tannin, with a specific focus on their utility in detecting and eliminating mercury from water sources. Subsequently, the most promising techniques and strategies involving wood and wood-derived biopolymers in addressing the predicament of mercury pollution are explored. Furthermore, this piece offers insights into the existing challenges and future prospects concerning environmentally friendly materials derived from wood, aiming to foster the development of cost-effective mercury adsorbents and detection devices.

Co-production of xylose, lignin, and ethanol from eucalyptus through a choline chloride-formic acid pretreatment.

A choline chloride-formic acid (ChCl-FA) pretreatment followed by enzymatic hydrolysis and fermentation were developed in this work for co-produce bioethanol, xylose, and lignin from eucalyptus. Results showed that ChCl-FA pretreatment can simultaneously degrade the xylan (∼95.2%) and lignin (∼74.4%) in eucalyptus, and obtained the pretreated eucalyptus having high glucan content and a numbers of cracks and holes, which was conducive to follow-up cellulase attacking. The hydrolysis experiments showed the maximum yield of glucose of 100 g eucalyptus was 35.3 g, which was equivalent to 90.3% of glucan in eucalyptus feedstock. The fermentation of enzymatic hydrolysate finally achieved the ethanol yield of 16.5 g, which corresponded to 74.5% theoretical ethanol yield from initial glucan in eucalyptus. In addition, 12.1 g xylose and 23.9 g lignin also could be obtained in pretreated liquid or/and hydrolysis residue, which represented for 61.4% xylan and 80.7% lignin in eucalyptus feedstock, respectively.

Lignin-silver triggered multifunctional conductive hydrogels for skinlike sensor applications.

Conductive hydrogels have attracted tremendous attention as a novel generation of wearable devices and body monitoring due to their great stretchability and high flexibility. Here, a multifunctional cellulose nanocrystal @sodium lignosulfonate-silver-poly(acrylamide) nanocomposite hydrogel was prepared by radical polymerization within only a few minutes. This polymerization rapidly occurred by lignosulfonate-silver (Ls-Ag) dynamic catalysis that efficiently activated ammonium persulfate (APS) to initiate the free-radical polymerization. In particular, the hydrogel exhibited excellent tensile strength (406 kPa), ultrahigh stretchability (1880 %), self-recovery, and fatigue resistance. Furthermore, due to the inclusion of Ls-Ag metal ion nanocomposite in the hydrogels, the composite hydrogel presented repeated adhesion to various objects, excellent conductivity (σ âˆ¼ 9.5 mS cm-1), remarkable UV resistance (100 % shielding of the UV spectral region), and high antibacterial activity (above 98 %), which enabled the hydrogel to be applied to epidermal sensors. In addition, the high-sensitivity (gauge factor of 2.46) sensor constructed of the hydrogel monitored the large and subtle movements of the human body and was used as a biological electrode to collect human electromyography and electrocardiographic signals. This work provided a novel strategy for the high-value utilization of lignin, which had potential application prospects in many fields such as wearable bioelectrodes.

Pretreatment of willow using the alkaline-catalyzed sulfolane/water solution for high-purity and antioxidative lignin production.

In this study, an alkaline-catalyzed sulfolane/water solvent system was developed for isolating high-purity and antioxidative lignin from willow (Salix matsudana cv. Zhuliu). Optimization of the pretreatment conditions such as temperature, sulfolane/water ratio, and alkaline catalyst (NaOH) dosage were comprehensively investigated for effective lignin extraction from willow. The 44.4% of lignin was recovered from the biomass with 54% of delignification in 50/50 (w/w) sulfolane/water system at 170 °C. As the addition of the alkaline catalyst (NaOH) increased to 4%, the delignification yield was increased up to 94% with about 70% of lignin recovery yield. The recovered lignin was comparatively investigated with its control, milled wood lignin (MWL). The ß-O-4 linkages and phenolic hydroxyl were well preserved in the extracted lignin fractions with the sulfolane/water system. Furthermore, excellent radical scavenging ability was observed with the extracted lignins by sulfolane/water pretreatments owing to rich phenolic hydroxyl groups in the lignins. Hence, systematical investigation on the lignin properties and potential applications under sulfolane organosolv pretreatment would promote the utilization of lignin in biorefinery processes.