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1.
Eur Respir J ; 42(6): 1524-35, 2013 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-23222882

RESUMO

This study aimed to assess the potential association of periodontal diseases with lung volumes and airflow limitation in a general adult population. Based on a representative population sample of the Study of Health in Pomerania (SHIP), 1463 subjects aged 25-86 years were included. Periodontal status was assessed by clinical attachment loss (CAL), probing depth and number of missing teeth. Lung function was measured using spirometry, body plethysmography and diffusing capacity of the lung for carbon monoxide. Linear regression models using fractional polynomials were used to assess associations between periodontal disease and lung function. Fibrinogen and high-sensitivity C-reactive protein (hs-CRP) were evaluated as potential intermediate factors. After full adjustment for potential confounders mean CAL was significantly associated with variables of mobile dynamic and static lung volumes, airflow limitation and hyperinflation (p<0.05). Including fibrinogen and hs-CRP did not change coefficients of mean CAL; associations remained statistically significant. Mean CAL was not associated with total lung capacity and diffusing capacity of the lung for carbon monoxide. Associations were confirmed for mean probing depth, extent measures of CAL/probing depth and number of missing teeth. Periodontal disease was significantly associated with reduced lung volumes and airflow limitation in this general adult population sample. Systemic inflammation did not provide a mechanism linking both diseases.


Assuntos
Pneumopatias/fisiopatologia , Periodontite/fisiopatologia , Adulto , Fatores Etários , Idoso , Idoso de 80 Anos ou mais , Proteína C-Reativa/metabolismo , Monóxido de Carbono/análise , Monóxido de Carbono/química , Estudos Transversais , Feminino , Fibrinogênio/metabolismo , Humanos , Inflamação , Modelos Lineares , Pulmão/fisiopatologia , Pneumopatias/complicações , Masculino , Pessoa de Meia-Idade , Periodontite/complicações , Pletismografia , Estudos Prospectivos , Respiração , Testes de Função Respiratória , Fatores Sexuais , Fumar/efeitos adversos , Espirometria
2.
J Clin Periodontol ; 36(7): 550-7, 2009 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-19538327

RESUMO

OBJECTIVES: Chronic subclinical inflammation may elevate the risk of cognitive impairment. Periodontitis is associated with subclinical inflammation and accounts in part for tooth loss. The hypothesis was tested that periodontitis and tooth loss as a proxy of chronic periodontitis is associated with cognitive impairment in the elderly. SUBJECTS AND METHODS: The population-based Study of Health in Pomerania comprises 1336 subjects (60-79 years). Cognitive impairment was assessed with the Mini-Mental Status Examination (MMSE). Tobit regression analyses were adjusted for potential confounders. RESULTS: A decreased number of teeth was associated with lower MMSE scores in females (p<0.001) and males (p=0.007) in age-adjusted models. In the fully adjusted models, tooth loss was associated with cognitive impairment in females (p=0.002) but not in males (p=0.825). CONCLUSIONS: A significant association between tooth loss and cognitive impairment was found in females that was not accounted for by potential confounders. Former periodontitis may account for this association as periodontitis was frequently the cause for tooth extractions.


Assuntos
Transtornos Cognitivos/epidemiologia , Periodontite/epidemiologia , Perda de Dente/epidemiologia , Idoso , Causalidade , Distribuição de Qui-Quadrado , Transtornos Cognitivos/diagnóstico , Comorbidade , Estudos Transversais , Feminino , Avaliação Geriátrica , Alemanha/epidemiologia , Humanos , Masculino , Entrevista Psiquiátrica Padronizada , Análise de Regressão , Fatores Sexuais , Fatores Socioeconômicos , Estatísticas não Paramétricas
3.
J Hypertens ; 25(10): 2035-43, 2007 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-17885545

RESUMO

OBJECTIVES: Recently, we have demonstrated a sex-specific inverse association between the number of teeth and hypertension. Left ventricular hypertrophy is a major cardiac sequel of hypertension. With the present study we sought to investigate whether there is also an inverse association between the number of teeth and left ventricular mass (LVM). METHODS: We used data from 1913 subjects (1036 women and 877 men) who were recruited for the population-based Study of Health in Pomerania (SHIP). The number of teeth, with the exception of the third molars, was counted in the full mouth. LVM was determined echocardiographically. Multivariable analyses were adjusted for major confounders. RESULTS: Women with fewer teeth had higher values for LVM than women with more teeth. This association was stable when controlled for major confounders. In the full model, edentulous women had an adjusted LVM of 178.4 g [95% confidence interval (CI) 170.4, 186.3 g] while women with 24-28 teeth had an adjusted LVM of 164.8 g (95% CI 156.8, 172.9 g; P < 0.01). In men, no such differences were observed. CONCLUSIONS: We conclude that there is an association between the number of teeth and LVM in women aged 45 years or older. In women, these findings further explain why poor oral health predicts all-cause and circulatory mortality. Further research in young, low-risk populations is needed to explore this association in men.


Assuntos
Ventrículos do Coração/anatomia & histologia , Dente/anatomia & histologia , Adulto , Idoso , Estudos Transversais , Dentição , Feminino , Alemanha , Ventrículos do Coração/patologia , Humanos , Hipertensão/complicações , Hipertensão/patologia , Hipertrofia Ventricular Esquerda/etiologia , Hipertrofia Ventricular Esquerda/patologia , Masculino , Pessoa de Meia-Idade , Fatores de Risco , Dente/patologia
4.
J Hypertens ; 24(7): 1257-63, 2006 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-16794473

RESUMO

BACKGROUND: Tooth loss predicts total and circulatory mortality. The reasons for the increased mortality in subjects with a low number of teeth may be related to enhanced atherosclerosis, elevated arterial pressure and more frequent hypertension. The present study was designed to investigate whether there is an association between the number of teeth and arterial pressure or hypertension. METHODS: We used data of 4185 adult subjects (2150 women) collected for the population-based Study of Health in Pomerania. The number of teeth was counted by trained and certified dentists. Hypertension was defined as systolic blood pressure >or= 140 mmHg or diastolic blood pressure >or= 90 mmHg or use of antihypertensive medication. Multivariable analyses were adjusted for relevant confounders. RESULTS: The adjusted mean (standard error) systolic blood pressure in men having 0-6 teeth was 149.6 mmHg (1.3 mmHg) compared to 142.6 mmHg (1.2 mmHg) in men having 27-28 teeth (P < 0.05). The adjusted odds for hypertension in men with 0-6 teeth compared to men with 27-28 teeth were 1.91 (95% confidence interval 1.21; 3.02, P < 0.05). In women no such relations were found. CONCLUSION: There is an inverse association between the number of teeth and systolic blood pressure and hypertension in men but not in women. The present findings partly explain the relation between tooth loss and mortality.


Assuntos
Pressão Sanguínea , Hipertensão/epidemiologia , Perda de Dente/epidemiologia , Adulto , Idoso , Anti-Hipertensivos/uso terapêutico , Pressão Sanguínea/fisiologia , Feminino , Alemanha/epidemiologia , Humanos , Hipertensão/tratamento farmacológico , Masculino , Pessoa de Meia-Idade , Análise de Regressão , Fatores de Risco , Fatores Sexuais , Perda de Dente/fisiopatologia
5.
Am Heart J ; 150(6): 1198-203, 2005 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-16338258

RESUMO

BACKGROUND: Several studies have shown that periodontal disease and atherosclerosis are associated. Aortic valve sclerosis (AVS) represents the sum of processes that are similar to the development of atherosclerosis. The present analysis was performed to investigate associations between periodontal disease, tooth loss, and AVS. METHODS: The population-based SHIP was conducted in northeast Germany. A study population of 2341 individuals aged > or =45 years was available for the present analysis. Aortic valve sclerosis was determined by echocardiography. Periodontal status was assessed by attachment loss and tooth loss. RESULTS: The prevalence of AVS was 29.9%. Logistic regression analyses did not reveal attachment loss as an independent risk factor for AVS. However, a reduced number of teeth was independently associated with AVS. Other risk factors for AVS were age, history of myocardial infarction, body mass index, pulse pressure, plasma fibrinogen and lipoprotein (a) levels, and the use of drugs that act on the renin-angiotensin system. CONCLUSION: A reduced number of teeth was independently associated with the risk of AVS. This finding further strengthens the link between oral health and cardiovascular disorders.


Assuntos
Valva Aórtica/patologia , Aterosclerose/epidemiologia , Perda de Dente/epidemiologia , Adulto , Idoso , Valva Aórtica/diagnóstico por imagem , Aterosclerose/diagnóstico por imagem , Ecocardiografia , Feminino , Alemanha/epidemiologia , Humanos , Incidência , Masculino , Pessoa de Meia-Idade , Doenças Periodontais/epidemiologia , Prevalência , Análise de Regressão , Fatores de Risco , Esclerose/epidemiologia
6.
Quintessence Int ; 36(1): 55-64, 2005 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-15709498

RESUMO

OBJECTIVE: The aim of this investigation was to evaluate the role of various signs and symptoms of temporomandibular disorders (TMD), among other potential risk factors, in developing frequent headache in a population-based sample of the cross-sectional epidemiologic Study of Health in Pomerania (SHIP). The impact of headache and of myogenous and arthrogenous signs of TMD on the quality of life of this sample was evaluated. METHOD AND MATERIALS: Medical history and dental and sociodemographic parameters of 4,255 subjects were checked for correlations with frequent headache using a multivariate logistic regression model. The quality of life of the headache sufferers was evaluated with a questionnaire on mental and physical health. RESULTS: Of the sample, 9% reported suffering from frequent headache. Significant values for the odds ratios for the whole sample were found for pain on palpation of the masticatory muscles; the anamnestic question on masticatory muscle pain; ear noises; lateral palpation pain of the temporomandibular joints (TMJ); several sleep disorders; psychosomatic complaints; and risk for women. Palpation pain of the muscles showed a dose/response effect. Subjects with a higher education level had a significantly reduced risk for developing frequent headache. Anamnestic questions for pain in the TMJ area, TMJ clicking, smoking, alcohol abuse, contraceptives, income, and chronic diseases did not correlate significantly with frequent headache. Subjects who reported frequent headache exhibited a significant reduction of physical and mental health scores. Pain upon muscle palpation showed significantly reduced scores on both scales for both genders. CONCLUSION: Within the limitations of this study, in addition to sensitive TMJs, mainly palpation-sensitive masticatory muscles showed a significant relation to the occurrence of frequent headache. Because of the number of tested covariates originally included in the model, this relation seems essential.


Assuntos
Cefaleia/epidemiologia , Qualidade de Vida , Transtornos da Articulação Temporomandibular/epidemiologia , Adulto , Idoso , Artralgia/epidemiologia , Estudos Transversais , Estudos Epidemiológicos , Dor Facial/epidemiologia , Feminino , Alemanha/epidemiologia , Cefaleia/psicologia , Nível de Saúde , Humanos , Masculino , Músculos da Mastigação/fisiopatologia , Saúde Mental , Pessoa de Meia-Idade , Palpação , Transtornos Psicofisiológicos/epidemiologia , Fatores de Risco , Fatores Sexuais , Transtornos do Sono-Vigília/epidemiologia , Som , Transtornos da Articulação Temporomandibular/psicologia
7.
Angle Orthod ; 75(2): 183-90, 2005 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-15825780

RESUMO

An analysis of exclusively representative population-based studies on adults has shown that only few and inconsistent associations could be detected between malocclusions and clinical signs of temporomandibular disorders (TMD)--and none for functional occlusion factors (occlusal interferences, non-working side contacts, etc). The aim of this study was to analyze associations between morphologic occlusion as well as factors of functional occlusion and subjectively perceived symptoms of TMD--again on the basis of the population-based Study of Health in Pomerania (SHIP), providing a sample of 4310 subjects (out of 7008 subjects yielding a response rate of 68.8%) aged 20 to 81 years, and other international representative studies from the systematic review. Besides occlusal factors also parafunctions and socioeconomic status (SES) were taken into account (including age and sex). Multiple logistic regression analysis was used--adjusted for SES. In this study, none of the occlusal factors were significantly associated with the indication of more frequent subjective TMD symptoms. However, the parafunction "frequent clenching" was connected with subjective TMD symptoms (odds ratio = 3.4). Compared with other population-based studies few and (across studies) inconsistent associations between malocclusions and subjective TMD symptoms could be ascertained. No significant associations of factors of functional occlusion with TMD symptoms were identifiable.


Assuntos
Má Oclusão/complicações , Transtornos da Articulação Temporomandibular/etiologia , Adulto , Fatores Etários , Idoso , Idoso de 80 Anos ou mais , Artralgia/etiologia , Bruxismo/complicações , Criança , Oclusão Dentária Traumática/complicações , Dor Facial/etiologia , Feminino , Alemanha , Humanos , Modelos Logísticos , Masculino , Pessoa de Meia-Idade , Razão de Chances , Fatores Sexuais , Classe Social
8.
Stroke ; 35(9): 2029-35, 2004 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-15256677

RESUMO

BACKGROUND AND PURPOSE: Males carry a disproportionate burden of cardiovascular disease. Because males also bear a higher burden of periodontal disease, we investigated the existence of gender differences in the postulated relationship between periodontal infections, tooth loss, and subclinical atherosclerosis. METHODS: A total of 1710 randomly enrolled participants between the ages of 45 and 75 with no history of myocardial infarction or stroke received a clinical periodontal examination, carotid scan using high-resolution B-mode ultrasound, and extensive measurements for conventional cardiovascular risk factors (age, education, smoking, alcohol, body mass index, diabetes, systolic blood pressure, low-density lipoprotein-cholesterol, high-density lipoprotein-cholesterol, and triglycerides) as well as markers of healthy lifestyle and social network. RESULTS: In both genders, measures of current and long-term periodontitis worsened as tooth loss increased. In males but not females, an approximately 10% difference in carotid artery plaque prevalence was observed between the lowest and highest tertiles of tooth loss (P<0.05) and long-term periodontitis (P=0.05) after multivariate adjustment. Similar patterns were observed for intima-media thickness. The influence of gender on carotid artery plaque prevalence was most evident among the younger age group (<59 years). Between genders, carotid plaque prevalence differed by 10%, 15%, and 25% across increasing levels of tooth loss, and by 5%, 15%, and 25% across increasing levels of long-term periodontitis. CONCLUSIONS: Our data suggest that tooth loss and long-term periodontitis are related to subclinical atherosclerosis in men but not women. Gender variations in cardiovascular morbidity or mortality may be explained partly by the differential contributions of novel risk factors across genders.


Assuntos
Arteriosclerose/epidemiologia , Periodontite/epidemiologia , Fatores Sexuais , Perda de Dente/epidemiologia , Idoso , Doenças das Artérias Carótidas/diagnóstico por imagem , Doenças das Artérias Carótidas/epidemiologia , Comorbidade , Estudos Transversais , Diabetes Mellitus/epidemiologia , Feminino , Alemanha/epidemiologia , Humanos , Estilo de Vida , Lipídeos/sangue , Masculino , Pessoa de Meia-Idade , Higiene Bucal , Fatores de Risco , Fumar/epidemiologia , Apoio Social , Ultrassonografia
9.
Thromb Haemost ; 92(2): 244-52, 2004 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-15269819

RESUMO

The systemic response to periodontal disease was analyzed in the cross-sectional Study of Health in Pomerania (SHIP). The completed data of 2,738 subjects aged 20 to 59 years were used for logistic regression analysis with an increased plasma fibrinogen level (> or =3.25 g/L according to Clauss) as the dependent variable. Participants were divided into four groups according to the number of periodontal pockets > or =4 mm (0, 1-7, 8-14, > or =15 pocketing). An additional group comprised the 52 edentulous subjects. The adjusted odds ratio (OR) of > or =15 periodontal pockets for increased plasma fibrinogen levels was 1.88 (95% CI: 1.25-2.83). Edentulism per se was not associated with increased plasma fibrinogen levels but was contained in a two-way interaction with the number of cigarettes/day in current smokers (p = 0.031). For edentulous nonsmokers the adjusted OR was 1.10 (95% CI: 0.51-2.39). Furthermore, body mass index, the interaction between gender and body mass index, serum LDL cholesterol, medication, the interaction between LDL cholesterol and medication, aspirin, smoking, school education, chronic bronchitis, and the interaction between alcohol consumption and chronic gastritis were associated with plasma fibrinogen levels. Our results show that periodontal disease but not edentulism per se is associated with an increased plasma fibrinogen level.


Assuntos
Fibrinogênio/biossíntese , Boca Edêntula/sangue , Doenças Periodontais/sangue , Adulto , Fatores Etários , Idoso , Consumo de Bebidas Alcoólicas , Índice de Massa Corporal , Doenças Cardiovasculares/sangue , LDL-Colesterol/metabolismo , Feminino , Fibrinogênio/metabolismo , Humanos , Modelos Logísticos , Masculino , Pessoa de Meia-Idade , Razão de Chances , Fatores Sexuais , Fatores de Tempo
10.
Quintessence Int ; 35(2): 143-50, 2004 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-15000638

RESUMO

OBJECTIVE: Based on a randomized, population study (Study of Health in Pomerania [SHIP]), the objective of the present study was to determine incidence of signs and symptoms of temporomandibular disorders (TMD) in adults 20 years or older and to compare the data with TMD prevalence of other exclusively random sample studies that fulfilled criteria similar to those of this study (age > or = 20 years, age range > or = 40 years, sample size > or = 500 subjects, equal gender distribution). METHOD AND MATERIALS: Men and women (n = 7,008) 20 to 79 years of age from mid- and small-sized towns in a rural region in northeast Germany were randomly sampled from resident registry office files. The response rate was 68.8%. Adults between the ages of 20 and 81 years (n = 4,289) were clinically and anamnestically examined. RESULTS: Half of the subjects (49.9%) had one or more clinical signs of TMD, but only 2.7% were subjectively aware of temporomandibular joint (TMJ) pain symptoms. Women showed higher frequency for all signs and symptoms of TMD than men. However, these differences were not significant for all signs and symptoms in all age groups. The influence of age on TMD signs and symptoms was less pronounced. The prevalence for the following variables found in the present study compared to those of other comparable, random sample studies was: clinical examination; (TMJ) tenderness to palpation (5% versus 2% to 6%); masticatory muscle tenderness (15% versus 19% to 21%); joint sounds (25% versus 15% to 25%); limited maximum mouth opening < 40 mm (9% versus 5% to 8%); pain upon movement of the mandible (1% versus 1% to 3%); irregular jaw movements (deviation, deflection) (28% versus 28%); interview: subjective joint sounds (9% versus 11% to 13%); and subjective TMJ pain (3% versus 4% to 7%). CONCLUSION: The TMD incidence in the current study agreed quite well with the other studies based on random samples with similar subjects and design. The large range of prevalence for signs and symptoms of TMD documented in reviews and meta-analyses could therefore not be confirmed.


Assuntos
Transtornos da Articulação Temporomandibular/epidemiologia , Adulto , Idoso , Dor Facial/epidemiologia , Feminino , Alemanha/epidemiologia , Inquéritos Epidemiológicos , Humanos , Incidência , Entrevistas como Assunto , Masculino , Pessoa de Meia-Idade , Palpação , Prevalência , Amplitude de Movimento Articular , Estudos de Amostragem , Razão de Masculinidade , Som
11.
Quintessence Int ; 34(5): 370-8, 2003 May.
Artigo em Inglês | MEDLINE | ID: mdl-12795357

RESUMO

The goal of the Study of Health in Pomerania (SHIP) was to estimate the prevalence of diseases, identify potential risk factors in a defined region in northeast Germany, and examine the particular living situation of this population after the reunification of East and West Germany. One of the main concerns of the SHIP design is the analysis of the relationships between dental, medical, social, and environmentally and behaviorally determined health factors. SHIP is a cross-sectional study (clinical findings and sociologic interviews). The sample was drawn in two steps: Thirty-two communities in the region were selected, and within these communities, a simple random sample was drawn from residence registries, stratified by gender and age. The final sample included 4,310 males and females, aged 20 to 79 years. This is equivalent to a participation rate of 68.8%. Data collection was completed in May 2001. The data collection and items comprised four parts: oral health examination, medical examination, health-related interview, and a health- and risk-factor-related questionnaire. The oral health examination included the teeth, periodontium, oral mucosa, morphology and function of the craniomandibular system, and prosthodontics. The medical examination included blood pressure measurements; electrocardiography; echocardiography; carotid, thyroid, and liver ultrasound examinations; neurologic screening; and blood and urine sampling. The computer-assisted interview consisted of questions on symptoms of disease, utilization of medical and dental services, self-assessment of general and oral health, health behavior and knowledge, and socioeconomic variables. The self-administered questionnaire comprised housing conditions, social network, work conditions, subjective well-being, and individual consequences of the German reunification.


Assuntos
Transtornos Craniomandibulares/epidemiologia , Cárie Dentária/epidemiologia , Inquéritos de Saúde Bucal , Doenças Periodontais/epidemiologia , Adulto , Idoso , Certificação , Estudos Transversais , Prótese Dentária/estatística & dados numéricos , Feminino , Alemanha/epidemiologia , Humanos , Masculino , Má Oclusão/epidemiologia , Pessoa de Meia-Idade , Prevalência , Controle de Qualidade , Projetos de Pesquisa
12.
Quintessence Int ; 34(10): 772-8, 2003.
Artigo em Inglês | MEDLINE | ID: mdl-14620269

RESUMO

OBJECTIVE: The aim of this study was to evaluate associations among the dental status, socioeconomic factors, and general health of 1,877 subjects between the ages of 55 and 79. METHOD AND MATERIALS: Socioeconomic information (age, sex, education level) and questions on smoking and alcohol abuse were taken from an interview; income and medical information (number of diseases) were taken from a self-administered questionnaire; and HbA1C and CDT (diabetes and alcoholism markers) were taken from blood analyses. RESULTS: Of the subjects, 73% had a low education level, and 27% of the subjects had a monthly income of < 1,000 Euro and 13% of > 2,000 Euro. Twenty-six percent of the subjects were edentulous, and 29% had 20 or more teeth. The odds ratio of edentulism increased to 9.0 (95% confidence interval = 7.0-11.5) at the ages of 75 to 79 years compared to ages 55 to 79. Logistic regression analyses showed that edentulism was significantly associated with age, low education level, low income, smoking, and alcohol abuse. However, the retention of more than 20 teeth was associated with age. CONCLUSIONS: Age, low income, low education level, smoking, and alcohol abuse seemed to be risk markers for edentulism; whereas, the number of diseases, diabetes, and gender were not.


Assuntos
Nível de Saúde , Boca Edêntula/epidemiologia , Distribuição por Idade , Idoso , Alcoolismo/epidemiologia , Estudos Transversais , Diabetes Mellitus/epidemiologia , Escolaridade , Feminino , Avaliação Geriátrica , Alemanha/epidemiologia , Humanos , Renda , Modelos Logísticos , Masculino , Pessoa de Meia-Idade , Razão de Chances , Distribuição por Sexo , Fumar/epidemiologia
13.
Angle Orthod ; 74(4): 512-20, 2004 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-15387030

RESUMO

The objective of this study was to determine whether associations exist between occlusal factors and signs of temporomandibular disorders (TMD) in adults using the population-based Study of Health in Pomerania (SHIP), Germany. A representative sample of 4310 men and women aged 20 to 81 years (response 68.8%) was investigated for TMD signs, malocclusions, functional occlusion factors, and sociodemographic parameters. Multiple logistic regression analysis, adjusted for sex, age, and socioeconomic status, was used. The results were compared with other population-based studies identified by a systematic review. Few malocclusions and no factors of functional occlusion except socioeconomic parameters were associated with TMD signs, and these associations were mostly weak. Only bilateral open bite up to three mm appeared to be clinically relevant and was associated with TMD signs (odds ratio [OR] = 4.0). This malocclusion, however, was of rare occurrence, with a prevalence of 0.3% (n = 9), and this finding was not confirmed by other representative studies. Occlusal factors examined in this study explained only a small part of the differences between normal subjects and those with TMD signs. This and other population-based studies indicate that malocclusions and factors of functional occlusion surveyed should be seen as merely cofactors in the sense of one piece of the mosaic in the multifactorial problem of temporomandibular dysfunction. Single occlusal factors that showed significant effects throughout several studies could not be detected. In view of the large number of occlusal variables already investigated, other variables including nonocclusal ones probably also play a role and should be looked at more intensely.


Assuntos
Mordida Aberta/complicações , Transtornos da Articulação Temporomandibular/complicações , Adulto , Fatores Etários , Idoso , Idoso de 80 Anos ou mais , Oclusão Dentária Balanceada , Métodos Epidemiológicos , Feminino , Alemanha , Humanos , Masculino , Má Oclusão/complicações , Pessoa de Meia-Idade , Fatores Sexuais , Fatores Socioeconômicos
14.
J Orofac Orthop ; 65(2): 88-103, 2004 Mar.
Artigo em Inglês, Alemão | MEDLINE | ID: mdl-15206092

RESUMO

AIM AND METHOD: The objective was to determine with reference to a representative sample of 4310 men and women aged 20 to 81 (response rate 68.8%) drawn from the population-based Study of Health in Pomerania (SHIP-0) whether associations exist between malocclusions and temporomandibular dysfunctions in adults. Besides clinically investigated signs, subjectively perceived symptoms of temporomandibular disorders (TMD) were studied in each individual together with malocclusions (plus normal occlusion), functional occlusion factors, and sociodemographic parameters. A multivariate logistic regression analysis was used, adjusted for age and discriminated for gender. The results were compared with those of other population-based studies identified by a systematic review undertaken by the present authors. RESULTS: Some malocclusions were associated with signs or symptoms of TMD but tended to occur only rarely: unilateral open bite, negative overjet, and unilateral scissors-bite in men, and edge-to-edge bite in women. However, malocclusions (and functional occlusion factors) accounted for only a small part of the differences between the control population and the study population with signs or symptoms of TMD. In terms of the multifactorial problem of temporomandibular disorders they should be seen as cofactors. The results, together with those of other population-based studies, revealed no specific, i.e. recurring malocclusions (or other occlusal factors) presenting as risk markers.


Assuntos
Má Oclusão/epidemiologia , Transtornos da Articulação Temporomandibular/epidemiologia , Adulto , Comorbidade , Estudos Transversais , Inquéritos de Saúde Bucal , Feminino , Alemanha/epidemiologia , Humanos , Modelos Logísticos , Masculino , Má Oclusão/diagnóstico , Transtornos da Articulação Temporomandibular/diagnóstico
15.
Schweiz Monatsschr Zahnmed ; 114(6): 573-80, 2004.
Artigo em Alemão | MEDLINE | ID: mdl-15315217

RESUMO

Aim of the study was to determine whether associations exist in men as well as in women between occlusal factors like malocclusions or factors of functional occlusion and subjective temporomandibular joint (TMJ) symptoms, based on the population-based Study of Health in Pomerania (SHIP-0). A representative sample of 4310 men and women (response rate 68.8%) aged 20 to 81 years was examined for subjective temporomandibular joint symptoms, malocclusions (incl. normal occlusion), factors of functional occlusion and for sociodemographic parameters. Men and women were analyzed separately with multiple logistic regression analyses, adjusted for age. The results were compared to other population-based studies from an own systematic review on this subject. In men and women, none of the 48 occlusal factors under survey (malocclusions or functional occlusion) was significantly more frequently associated with the dependent variable "subjective temporomandibular joint symptoms". In contrast, the parafunction "frequent clenching" was associated more frequently and clinically relevant with TMJ symptoms in both sexes (for men, odds ratio = 4.2, prevalence 4.9%; for women OR = 2.9, prevalence 5.6%). Malocclusions and functional occlusion factors only explained a smaller part of the differences between the male and female population with and without subjective TMJ symptoms. Compared to other population-based studies only few and inconsistent associations between occlusal factors and subjective temporomandibular symptoms were ascertainable in both sexes.


Assuntos
Má Oclusão/psicologia , Síndrome da Disfunção da Articulação Temporomandibular/psicologia , Adulto , Idoso , Bruxismo/complicações , Feminino , Alemanha/epidemiologia , Humanos , Modelos Logísticos , Masculino , Má Oclusão/complicações , Pessoa de Meia-Idade , Razão de Chances , Prevalência , Autorrevelação , Fatores Sexuais , Classe Social , Síndrome da Disfunção da Articulação Temporomandibular/epidemiologia , Síndrome da Disfunção da Articulação Temporomandibular/etiologia
16.
Br J Clin Pharmacol ; 60(5): 552-9, 2005 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-16236046

RESUMO

AIM: Gingival overgrowth is a common undesired side-effect in patients taking calcium channel blockers. Different reports have suggested that the drug-induced gingival hyperplasia may aggravate inflammatory periodontal disease. However, representative epidemiological data are lacking. We investigated the association between the intake of calcium antagonists and periodontitis in a population-based analysis including the most important risk factors of periodontitis. METHODS: In a cross-sectional epidemiological investigation involving 4290 subjects aged 20-80 years, we recorded periodontal risk factors and identified participants using calcium antagonists. Periodontal parameters, attachment loss, probing depth and number of teeth were assessed. In a subgroup analysis with matched pairs, 456 subjects using calcium antagonists and 456 without were compared for periodontal status. RESULTS: Subjects treated with calcium antagonistic drugs had significantly deeper gingival pockets than their drug-free counterparts. This was observed in the total population of 4290 and confirmed by logistic regression analyses (P < 0.001) controlled for the known risk factors of periodontitis (age, sex, smoking, education). In the matched-pair analysis only the probing depth was increased: extent probing depth > or = 4 mm median 23.5 vs. 17.0% (P < 0.001); mean probing depth 3.0 +/- 0.8 vs. 2.7 +/- 0.9 mm (P < 0.001). No differences were found in extent and severity of clinical attachment loss and in the number of teeth. The risk of gingival overgrowth was aggravated in smokers. CONCLUSION: In the general population, treatment with calcium antagonists leads to gingival overgrowth without an aggravation of periodontal disease. Interaction with smoking indicates the multifactorial background of the undesired effect of calcium antagonists.


Assuntos
Bloqueadores dos Canais de Cálcio/efeitos adversos , Periodontite/induzido quimicamente , Adulto , Distribuição por Idade , Idoso , Idoso de 80 Anos ou mais , Métodos Epidemiológicos , Feminino , Alemanha/epidemiologia , Humanos , Masculino , Pessoa de Meia-Idade , Periodontite/epidemiologia , Fumar/efeitos adversos , Fumar/epidemiologia
17.
Int J Prosthodont ; 18(3): 232-9, 2005.
Artigo em Inglês | MEDLINE | ID: mdl-15945311

RESUMO

PURPOSE: The aim of this study was to investigate whether gender-dependent associations exist between signs of temporomandibular disorders (TMD) and occlusal support. MATERIALS AND METHODS: Stratified by gender, the data of 2,963 35- to 74-year-old participants from the epidemiologic Study of Health in Pomerania were used in logistic regression analyses with temporomandibular joint (TMJ) tenderness and muscle tenderness as the dependent variables. Occlusal support was classified according to the Eichner index, a classification system based on occluding pairs of teeth. The final model was adjusted for bruxism, age, and various sociodemographic data. RESULTS: Logistic regression analyses revealed increased odds ratios for TMJ tenderness in men with loss of all four molar and premolar supporting zones (odds ratio 3:9) and without antagonist contact (odds ratio 2:7). Significant relationships in men were also found between muscle tenderness and loss of one (odds ratio 2:1), three (odds ratio 2:1), or four supporting zones (odds ratio 2:7), and loss of any tooth contact (odds ratio 2:3). In women, significant associations between occlusal support and TMD signs were absent. Subjects with bruxism were more likely to have TMJ tenderness (odds ratio women 2:0, men 1:9). In women, an additional relationship existed between bruxism and muscle tenderness (odds ratio 1:7). The following habits showed no significance: gum chewing, unilateral chewing, and lip/tongue/cheek biting. CONCLUSION: Only in men was the loss of occlusal support significantly associated with muscle and TMJ tenderness. The association between bruxism and TMD signs supports the theory that repetitive adverse loading of the masticatory system may cause functional disturbances.


Assuntos
Oclusão Dentária , Transtornos da Articulação Temporomandibular/epidemiologia , Adulto , Fatores Etários , Idoso , Dente Pré-Molar , Bruxismo/epidemiologia , Bochecha/lesões , Goma de Mascar/estatística & dados numéricos , Estudos Transversais , Estudos Epidemiológicos , Feminino , Alemanha/epidemiologia , Humanos , Lábio/lesões , Masculino , Má Oclusão/epidemiologia , Mastigação , Pessoa de Meia-Idade , Dente Molar , Vigilância da População , Fatores Sexuais , Língua/lesões , Perda de Dente/epidemiologia
18.
Int J Prosthodont ; 18(5): 414-9, 2005.
Artigo em Inglês | MEDLINE | ID: mdl-16220807

RESUMO

PURPOSE: It is important to know whether tooth loss has an impact on an individual's quality of life, since tooth loss is common. The aim of this study was to determine whether oral status is associated with general health and related to quality of life. MATERIALS AND METHODS: Data of 1,406 subjects aged 60 to 79 years were taken from the Study of Health in Pomerania (SHIP). Sociodemographic (age, sex, and education level) and medical information (including the most common diseases in Germany) were gathered through an interview, and income data were obtained from a self-administered questionnaire. The prosthetic status in the maxilla and mandible was classified into complete denture or removable partial denture or with > or = 10 natural teeth including teeth replaced with fixed prosthodontics (> or = 10T) or with < or = 9 natural teeth including fixed prosthodontics (< or = 9T). The health-related quality of life was measured using the Short Form (SF-12) questionnaire. Multiple linear logistic regression analyses were used to identify the nonstandardized beta coefficient using physical and psychologic indices from the SF-12 as dependent variables and sociodemographic information, prosthetic status, and disease state as independent variables. RESULTS: Prosthetic status is related to the physical scale of the SF-12. Additionally, we found that < or = 9T had a significant effect on the physical index of general health-related quality of life. CONCLUSION: Reduced dentition without replacement of missing teeth by removable or fixed prosthodontics reduces the physical index of quality of life to the same extent as cancer or renal diseases.


Assuntos
Prótese Total/psicologia , Prótese Parcial Removível/psicologia , Arcada Edêntula/psicologia , Qualidade de Vida , Perda de Dente/psicologia , Idoso , Escolaridade , Feminino , Alemanha , Nível de Saúde , Humanos , Modelos Lineares , Masculino , Pessoa de Meia-Idade , Inquéritos e Questionários
19.
Int J Prosthodont ; 17(3): 333-9, 2004.
Artigo em Inglês | MEDLINE | ID: mdl-15237882

RESUMO

PURPOSE: Using a population-based sample of the cross-sectional epidemiologic "Study of Health in Pomerania" (SHIP), this study evaluated whether certain occlusal and sociodemographic factors besides age and gender are risk factors for high dental wear. MATERIALS AND METHODS: Medical history and dental and sociodemographic parameters of 2,529 dentate subjects selected representatively and according to age distribution were checked for correlations with the occurrence of high occlusal wear symptoms using a multivariate logistic regression model. Occlusal wear was recorded using the attrition index by Ekfeldt et al and was age adjusted by determining high occlusal wear for every 10-year age group as index values > or = 90th percentile. RESULTS: The following independent variables were found to be correlated with high occlusal wear: male gender, odds ratio 2.2; frequent bruxism, odds ratio 2.5; loss of molar occlusal contact (Eichner classification), odds ratio from 1.5 to 3.1; edge-to-edge relation of incisors, odds ratio 1.7; unilateral buccolingual cusp-to-cusp relation, odds ratio 1.8; and unemployment, odds ratio 1.6. In contrast, anterior cross-bite, unilateral posterior cross-bite, and anterior crowding were protective for high occlusal wear levels, as shown by significantly reduced odds ratios. Gender-separated analysis showed that self-reported bruxism was a risk factor only for men. CONCLUSION: In addition to some occlusal factors, the main factors associated with occlusal wear were bruxism and gender.


Assuntos
Abrasão Dentária/epidemiologia , Atrito Dentário/epidemiologia , Adulto , Distribuição por Idade , Idoso , Força de Mordida , Bruxismo/complicações , Feminino , Alemanha/epidemiologia , Humanos , Modelos Logísticos , Masculino , Má Oclusão/complicações , Pessoa de Meia-Idade , Prevalência , Fatores de Risco , Fatores Sexuais , Fatores Socioeconômicos , Abrasão Dentária/etiologia , Atrito Dentário/etiologia
20.
Gerodontology ; 21(1): 27-36, 2004 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-15074537

RESUMO

OBJECTIVE: The aim of this study was to describe the oral health status of older adults living in northeastern Germany. MATERIALS AND METHODS: Representative samples of adults aged 60 years or older were examined as part of Study of the Health in Pomerania, a cross-sectional, population-based study. Data on 1446 subjects aged 60-79 years were evaluated for coronal caries using the decayed/missing/filled teeth (DMFT) index, root caries using the root caries index (RCI), calculus, plaque, bleeding on probing, pocket depth and attachment loss. RESULTS: The prevalence of edentulousness varied from 16% in the 60-65-year-old group to 30% in the 75-79-year-old group, whereas the median number of remaining natural teeth per subject varied from 14 in the youngest age group (60-65 years) to one in the oldest (75-79 years). Among subjects aged 60-69 years, a quarter (26%) of the teeth examined had coronal restoration against 17% in the oldest age group (70-79 years). Coronal caries was found in 2% of the teeth in both age groups. Among teeth with gingival recession, 6% had fillings on root surfaces and 2% had root caries, irrespective of age. In all, 11% of the subjects had at least one untreated coronal lesion and 27% had at least one untreated root caries lesion. Plaque score, calculus score and bleeding on probing were higher in the oldest age group (70-79 years). The prevalence of periodontal disease expressed as the presence of at least one periodontal pocket of 4 mm and more, was higher in men and among the younger subjects (men aged 60-69 years: 85% vs. 71% in 70-79-year-old men; women aged 60-69 years: 71% vs. 62% in 70-79-year-olds). The prevalence of attachment loss of 3 mm or more followed a similar pattern. CONCLUSIONS: It seems therefore that in this population, the major oral health concern is related to caries and the small number of teeth retained among the dentate subjects.


Assuntos
Cárie Dentária/epidemiologia , Doenças Periodontais/epidemiologia , Fatores Etários , Idoso , Estudos Transversais , Índice CPO , Cálculos Dentários/epidemiologia , Placa Dentária/epidemiologia , Restauração Dentária Permanente/estatística & dados numéricos , Feminino , Alemanha/epidemiologia , Hemorragia Gengival/epidemiologia , Humanos , Masculino , Pessoa de Meia-Idade , Boca Edêntula/epidemiologia , Perda da Inserção Periodontal/epidemiologia , Bolsa Periodontal/epidemiologia , Vigilância da População , Prevalência , Cárie Radicular/epidemiologia , Fatores Sexuais
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