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1.
BMC Oral Health ; 18(1): 10, 2018 01 10.
Artigo em Inglês | MEDLINE | ID: mdl-29321012

RESUMO

BACKGROUND: The purpose of this study was to gain an in-depth understanding of Arabic-speaking mothers views on the usefulness of existing oral health education leaflets aimed at young children and also to record their views on the tailored versions of these leaflets. METHODS: This qualitative study was nested within a large ongoing birth cohort study in South Western Sydney, Australia. Arabic-speaking mothers (n = 19) with young children were purposively selected and approached for a semi-structured interview. Two original English leaflets giving advice on young children's oral health were sent to mother's prior to the interview. On the day of interview, mothers were given simplified-English and Arabic versions of both the leaflets and were asked to compare the three versions. Interviews were audio-recorded, subsequently transcribed verbatim and analysed by thematic analysis. Ethical approval was obtained from Human Research Ethics Committees of the former Sydney South West Area Health Service, University of Sydney and Western Sydney University. RESULTS: Mothers reported that simplified English together with the Arabic version of the leaflets were useful sources of information. Although many mothers favoured the simplified version over original English leaflets, the majority favoured the leaflets in Arabic. Ideally, a "dual Arabic - simplified English leaflet" was preferred. The understanding of key health messages was optimised through a simple layout and visual images. CONCLUSIONS: There is a need to tailor oral health education leaflets for Arabic-speaking migrants. Producers of dental leaflets should also consider a "dual Arabic - simplified English leaflet" to improve oral health knowledge of Arabic-speaking migrants. The use of simple layout and pictures assists Arabic-speaking migrants to understand the content of dental leaflets.


Assuntos
Árabes , Emigrantes e Imigrantes/educação , Saúde Bucal/educação , Educação de Pacientes como Assunto/métodos , Adulto , Austrália , Criança , Saúde da Criança , Escolaridade , Feminino , Humanos , Lactente , Entrevistas como Assunto , Mães/educação , Pesquisa Qualitativa , Adulto Jovem
2.
J Biomed Opt ; 22(9): 1-5, 2017 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-28925108

RESUMO

Optically scattering phantoms composed of silica microspheres embedded in an optically clear silicone matrix were manufactured using a previously developed method. Multiple problems, such as sphere aggregation, adsorption to the cast, and silicone shrinkage, were, however, frequently encountered. Solutions to these problems were developed and an improved method, incorporating these solutions, is presented. The improved method offers excellent reliability and reproducibility for creating phantoms with uniform scattering coefficient. We also present evidence of decreased sphere aggregation.


Assuntos
Microesferas , Imagens de Fantasmas , Dióxido de Silício , Silicones , Reprodutibilidade dos Testes
3.
J Am Coll Cardiol ; 59(17): 1539-48, 2012 Apr 24.
Artigo em Inglês | MEDLINE | ID: mdl-22516444

RESUMO

OBJECTIVES: With combined positron emission tomography and computed tomography (CT), we investigated coronary arterial uptake of 18F-sodium fluoride (18F-NaF) and 18F-fluorodeoxyglucose (18F-FDG) as markers of active plaque calcification and inflammation, respectively. BACKGROUND: The noninvasive assessment of coronary artery plaque biology would be a major advance particularly in the identification of vulnerable plaques, which are associated with specific pathological characteristics, including micro-calcification and inflammation. METHODS: We prospectively recruited 119 volunteers (72 ± 8 years of age, 68% men) with and without aortic valve disease and measured their coronary calcium score and 18F-NaF and 18F-FDG uptake. Patients with a calcium score of 0 were used as control subjects and compared with those with calcific atherosclerosis (calcium score >0). RESULTS: Inter-observer repeatability of coronary 18F-NaF uptake measurements (maximum tissue/background ratio) was excellent (intra-class coefficient 0.99). Activity was higher in patients with coronary atherosclerosis (n = 106) versus control subjects (1.64 ± 0.49 vs. 1.23 ± 0.24; p = 0.003) and correlated with the calcium score (r = 0.652, p < 0.001), although 40% of those with scores >1,000 displayed normal uptake. Patients with increased coronary 18F-NaF activity (n = 40) had higher rates of prior cardiovascular events (p = 0.016) and angina (p = 0.023) and higher Framingham risk scores (p = 0.011). Quantification of coronary 18F-FDG uptake was hampered by myocardial activity and was not increased in patients with atherosclerosis versus control subjects (p = 0.498). CONCLUSIONS: 18F-NaF is a promising new approach for the assessment of coronary artery plaque biology. Prospective studies with clinical outcomes are now needed to assess whether coronary 18F-NaF uptake represents a novel marker of plaque vulnerability, recent plaque rupture, and future cardiovascular risk. (An Observational PET/CT Study Examining the Role of Active Valvular Calcification and Inflammation in Patients With Aortic Stenosis; NCT01358513).


Assuntos
Doença da Artéria Coronariana/diagnóstico por imagem , Radioisótopos de Flúor/farmacocinética , Fluordesoxiglucose F18/farmacocinética , Tomografia por Emissão de Pósitrons , Fluoreto de Sódio/farmacocinética , Idoso , Aorta Torácica/diagnóstico por imagem , Aorta Torácica/patologia , Biomarcadores/análise , Angiografia Coronária/métodos , Vasos Coronários/diagnóstico por imagem , Vasos Coronários/patologia , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Variações Dependentes do Observador , Estudos Prospectivos , Reprodutibilidade dos Testes , Medição de Risco , Sensibilidade e Especificidade , Índice de Gravidade de Doença , Tomografia Computadorizada por Raios X
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