Alveolar osteotomy associated with resorbable non-ceramic hydroxylapatite or intra-oral autogenous bone for height augmentation in posterior mandibular sites: a split-mouth prospective study.

BACKGROUND: The presence of the inferior alveolar nerve within the body of the mandible could jeopardize the placement of dental implants. Previous studies have shown that the interpositional osteotomy for posterior mandible ridge augmentation could be a predictable procedure. Nevertheless, there are few prospective, controlled, and randomized studies that evaluated this technique using different bone graft materials. PURPOSE: This prospective, controlled split-mouth study evaluated, using tomographic and Resonance Frequency Analyses (RFA), implants placed in the augmented mandibular area. MATERIAL AND METHODS: Alveolar augmentation osteotomies were performed bilaterally in 12 partially edentulous mandibular patients in a split-mouth design. The alveolar segmental osteotomies were assigned in two groups: test group, interpositional non-ceramic hydroxylapatite bone graft, and control group, interpositional intra-oral autogenous bone graft. After 6 months healing, implants were placed. The tomographic measurements of bone gain were recorded at baseline and 6 months after surgery, when the implants were placed. At 12 months after osteotomy, RFA were performed for each implant. RESULTS: The mean of bone gain 6.5 ± 2.4 mm and 7.0 ± 1.76 mm to control and test group, respectively (P > 0.05). RFA values between groups were similar at baseline and 12 months follow-up (P > 0.05). CONCLUSION: Alveolar osteotomies associated with sandwich interpositional bone graft, independently of bone graft, resulted in bone formation over a period of 12 months.

Effect of anesthetics containing lidocaine and epinephrine on cardiovascular changes during dental implant surgery.

The purpose of this study was to evaluate cardiovascular changes during dental implant surgery using 2% lidocaine with 1:80 000 epinephrine. Eleven normotensive subjects, ranging from 18 to 56 years, were selected to undergo dental implant surgery in the jaw. They were monitored in the pre-, intra-, and postsurgical periods by continuous noninvasive automatic arterial pressure and cardiac frequency measurements taken every 2 minutes. Parameter scores were obtained for the following phases: P1, 15 minutes during preparation of the patient (control period); P2, before anesthesia; P3, immediately after anesthesia; P4, 2 minutes into anesthesia; P5, during incision and detachment; P6, during perforation; P7, during implant placement; P8, during suturing; P9, on completion; and P10, 10 minutes after termination. Individualized statistical analysis for each group during the pre-, intra-, and postoperative periods were performed by analysis of variance. The greatest variations in systolic pressure were increases of 2.29% during phase P2 and 2.59% in phase P5. Diastolic pressure decreased during phase P6 (-2.58%) and increased in P10 (3.27%). The greatest changes in heart rate occurred in phase P10 (-3.24%). There were no statistically significant changes among the evaluated phases (P > .05). In conclusion, there were no changes in the analyzed cardiocirculatory parameters during dental implant surgery (systolic, diastolic, and mean arterial blood pressures and heart rate) in normotensive subjects anesthetized with 2% lidocaine with epinephrine 1:80000.

A histological study of non-ceramic hydroxyapatite as a bone graft substitute material in the vertical bone augmentation of the posterior mandible using an interpositional inlay technique: A split mouth evaluation.

The aim of this study was to compare the influence of graft material (non-ceramic hydroxyapatite versus autologous bone) on bone behaviour and perform a resonance frequency analysis of implants placed in augmented sites to evaluate stability. For this study, 11 patients with bilateral edentulous areas in the mandibular posterior region were selected. Alveolar augmentation osteotomies were bilaterally (split mouth design) performed. In one hemiarch, the space generated by the osteotomy was grafted with an interpositional intra-oral autologous bone graft (control group). In the other hemiarch, the space generated by the osteotomy was grafted with an interpositional non-ceramic hydroxyapatite (ncHA) (test group). The groups were randomized. After 6 months of healing, a bone sample was retrieved from each side for histological evaluation using a trephine drill that was 2-mm in internal diameter. The implant stability quotient (ISQ) was measured by the resonance frequency immediately following implant placement at baseline and after 6 months of follow-up. Good incorporation of the graft was observed in both groups; however, in the test group, a residual-grafted material was observed. Bone density and marrow spaces were similar between groups. Correlations between the ISQ values and the histometric variables were not observed (p>0.05). The results of this trial suggest that both intra-oral autologous bone and ncHA may be elected as interpositional grafting materials to vertically augment posterior atrophic mandibles.

Stability of implants placed in augmented posterior mandible after alveolar osteotomy using resorbable nonceramic hydroxyapatite or intraoral autogenous bone: 12-month follow-up.

PURPOSE: This prospective, controlled split-mouth study evaluated the stability of dental implants placed in the augmented mandibular areas with alveolar segmental "sandwich" osteotomies using nonceramic hydroxyapatite (ncHA) or autogenous bone. MATERIAL AND METHODS: This study included 11 bilaterally partially edentulous mandibular patients in a split-mouth design. Alveolar augmentation osteotomies were performed bilaterally with interpositional ncHA graft (test group) or interpositional intraoral autogenous bone graft (control group). After 6 months of healing, four implants (two implants in each side) were placed in each patient. Forty-four implants were inserted and loaded after 6-month healing period. At 1-year follow-up, radiographic, prosthetic, and resonance frequency analysis parameters were assessed. Success criteria included absence of pain, sensitivity, suppuration, and implant mobility; absence of continuous peri-implant radiolucency; and distance between the implant shoulder and the first visible bone contact (DIB) < 2 mm. RESULTS: After a 1-year loading period, the overall implant survival rate was 95.45%, with two implant losses (one of each group). Among the surviving implants (42 out of 44), two did not fulfill the success criteria; therefore, the implant success was 90.90%. DIB was 0.71 ± 0.70 and 0.84 ± 0.72 mm for ncHA and autogenous bone grafts, respectively (p > .05). Implant stability measurements were similar between the groups during the 12-month follow-up (p > .05). CONCLUSION: Within the limits of this study, the implants placed either in sites augmented with ncHA or autogenous bone seem to represent a safe and successful procedure, at least, after 12-month follow-up.

Influência de diferentes topografias de implantes sobre o tecido ósseo peri-implantar humano / Influence of different implant tomographies on human peri-implant bone tissue

O principal parâmetro para avaliação do sucesso dos implantes osseointegrados é baseado no percentual do contato do tecido ósseo à superfície do implante. Este processo depende de vários fatores que vão desde a inserção do implante no leito cirúrgico e a formação do coágulo sanguíneo a todos os eventos celulares relacionados à biologia óssea peri-implantar. Logo, o objetivo deste estudo foi avaliar, de maneira sistemática, a sequência de eventos celulares assim como os fatores que influenciam a qualidade e a quantidade de contato do tecido ósseo humano a superfície do implante e suas consequências clínicas.