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1.
Br J Psychol ; 113(1): 264-286, 2022 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-34541676

RESUMO

In most studies of facial attractiveness perception, judgments are based on the whole face images. Here we investigated how attractiveness judgments from parts of faces compare to perceived attractiveness of the whole face, and to each other. We manipulated the extent and regions of occlusion, where either the left/right or the top/bottom half of the face was occluded. We also further segmented the face into relatively small horizontal regions involving the forehead, eyes, nose, or mouth. The results demonstrated the correlated nature of face regions, such that an attractiveness judgment for one face part can be highly predictive of the attractiveness of the whole face or the other parts. The left/right half of the face created more accurate predictions than the top/bottom half. Judgments involving a larger area of the face (i.e., left/right or top/bottom halves) produced more accurate predictions than those derived from smaller regions, such as the eyes or the mouth alone, but even the smallest and most featureless region investigated (the forehead) provided useful information. The correlated nature of the attractiveness of face parts shows that perceived attractiveness is determined by multiple covarying cues that the visual system can exploit to determine attractiveness from a single glance.


Assuntos
Beleza , Sinais (Psicologia) , Olho , Face , Humanos , Julgamento
2.
Bioorg Med Chem ; 18(7): 2447-55, 2010 Apr 01.
Artigo em Inglês | MEDLINE | ID: mdl-20304657

RESUMO

We described here the design, synthesis, molecular modeling, and biological evaluation of a series of peptide and Schiff bases (PSB) small molecules, inhibitors of Escherichia coli beta-Ketoacyl-acyl carrier protein synthase III (ecKAS III). The initial lead compound was reported by us previously, we continued to carry out structure-activity relationship studies and optimize the lead structure to potent inhibitors in this research. The results demonstrated that both N-(2-(3,5-dichloro-2-hydroxybenzylideneamino)propyl)-2-hydroxybenzamide (1f) and 2-hydroxy-N-(2-(2-hydroxy-5-iodobenzylideneamino)propyl)-4-methylbenzamide (3e) posses good ecKAS III inhibitory activity and well binding affinities by bonding Gly152/Gly209 of ecKAS III and fit into the mouth of the substrate tunnel, and can be as potential antibiotics agent, displaying minimal inhibitory concentration values in the range 0.20-3.13microg/mL and 0.39-3.13microg/mL against various bacteria.


Assuntos
Antibacterianos/síntese química , Antibacterianos/farmacologia , Bactérias/efeitos dos fármacos , Bactérias/enzimologia , Peptídeos/síntese química , Peptídeos/farmacologia , Bases de Schiff/síntese química , Bases de Schiff/farmacologia , 3-Oxoacil-(Proteína de Transporte de Acila) Sintase/antagonistas & inibidores , Domínio Catalítico/efeitos dos fármacos , Biologia Computacional , Cristalografia por Raios X , Inibidores Enzimáticos/síntese química , Inibidores Enzimáticos/farmacologia , Escherichia coli/efeitos dos fármacos , Escherichia coli/enzimologia , Indicadores e Reagentes , Ligantes , Espectroscopia de Ressonância Magnética , Testes de Sensibilidade Microbiana , Modelos Moleculares , Ligação Proteica , Espectrometria de Massas por Ionização por Electrospray
3.
Q J Exp Psychol (Hove) ; 68(2): 249-60, 2015.
Artigo em Inglês | MEDLINE | ID: mdl-25203612

RESUMO

For familiar faces, the internal features (eyes, nose, and mouth) are known to be differentially salient for recognition compared to external features such as hairstyle. Two experiments are reported that investigate how this internal feature advantage accrues as a face becomes familiar. In Experiment 1, we tested the contribution of internal and external features to the ability to generalize from a single studied photograph to different views of the same face. A recognition advantage for the internal features over the external features was found after a change of viewpoint, whereas there was no internal feature advantage when the same image was used at study and test. In Experiment 2, we removed the most salient external feature (hairstyle) from studied photographs and looked at how this affected generalization to a novel viewpoint. Removing the hair from images of the face assisted generalization to novel viewpoints, and this was especially the case when photographs showing more than one viewpoint were studied. The results suggest that the internal features play an important role in the generalization between different images of an individual's face by enabling the viewer to detect the common identity-diagnostic elements across non-identical instances of the face.


Assuntos
Aprendizagem por Discriminação/fisiologia , Face , Reconhecimento Visual de Modelos/fisiologia , Reconhecimento Psicológico/fisiologia , Adolescente , Adulto , Análise de Variância , Feminino , Percepção de Forma , Humanos , Masculino , Pessoa de Meia-Idade , Estimulação Luminosa , Adulto Jovem
4.
Nan Fang Yi Ke Da Xue Xue Bao ; 34(9): 1386-9, 2014 Aug.
Artigo em Zh | MEDLINE | ID: mdl-25263382

RESUMO

OBJECTIVE: To investigate the effect of cetylpyridinium chloride buccal tablets on halitosis induced by oral conditions. METHODS: With Porphyromonas gingivalis, Prevotella intermedia and Fusobacterium nucleatum as the testing bacteria, the minimal inhibitory concentration (MIC) of cetylpyridinium chloride buccal tablets was determined using minute amount serial dilution test. The production of volatile sulfur compounds (VSCs) was measured using sulfide detector halimeter in the anaerobic bacteria culture at 4 and 8 h after addition of the tablets. The effect of the tablets in suppressing odor production by mouth-borne halitosis bacteria was assessed using cysteine challenge test in healthy volunteers, and the effectiveness was evaluated by measuring the reduction in VSCs production and the duration of the effect. RESULTS: Cetylpyridinium chloride buccal tablets inhibited the growth of all the 3 bacteria. The tablets obviously inhibited VSCs production by the 3 bacteria with a effect similar to chlorhexidine. Compared with distilled water gargle, the buccal tablets significantly reduced cysteine-induced VSCs production level in the healthy volunteers (P<0.05), and the effect lasted for 230 min. CONCLUSION: Cetylpyridinium chloride tablets can obviously suppress bacteria responsible for oral halitosis and produce good effects in the treatment of halitosis induced by oral conditions.


Assuntos
Cetilpiridínio/uso terapêutico , Halitose/tratamento farmacológico , Fusobacterium nucleatum/efeitos dos fármacos , Humanos , Testes de Sensibilidade Microbiana , Porphyromonas gingivalis/efeitos dos fármacos , Prevotella intermedia/efeitos dos fármacos , Compostos de Enxofre/análise , Comprimidos , Compostos Orgânicos Voláteis/análise
5.
J Exp Psychol Learn Mem Cogn ; 38(1): 61-77, 2012 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-21823809

RESUMO

Describing a face in words can either hinder or help subsequent face recognition. Here, the authors examined the relationship between the benefit from verbally describing a series of faces and the same-race advantage (SRA) whereby people are better at recognizing unfamiliar faces from their own race as compared with those from other races. Verbalization and the SRA influenced face recognition independently, as evident on both behavioral (Experiment 1) and eye movement measures (Experiment 2). The findings indicate that verbalization and the SRA each recruit different types of configural processing, with verbalization modulating face learning and the SRA modulating both face learning and recognition. Eye movement patterns demonstrated greater feature sampling for describing as compared with not describing faces and for other-race as compared with same-race faces. In both cases, sampling of the eyes, nose, and mouth played a major role in performance. The findings support a single process account whereby verbalization can influence perceptual processing in a flexible and yet fundamental way through shifting one's processing orientation.


Assuntos
Movimentos Oculares/fisiologia , Face , Reconhecimento Visual de Modelos/fisiologia , Reconhecimento Psicológico/fisiologia , Detecção de Sinal Psicológico/fisiologia , Aprendizagem Verbal/fisiologia , Adulto , Análise de Variância , Povo Asiático , Discriminação Psicológica , Feminino , Humanos , Masculino , Tempo de Reação/fisiologia , População Branca , Adulto Jovem
6.
Shanghai Kou Qiang Yi Xue ; 15(1): 15-8, 2006 Feb.
Artigo em Zh | MEDLINE | ID: mdl-16525601

RESUMO

PURPOSE: To evaluate antibacterial effects of Jinzhi Hanshuye on infected root canals. METHODS: 30 infected single-root-canals were collected from 27 clinical patients, and randomly divided into two groups. In the experimental group, Jinzhi Hanshuye was used as irrigating solution and intracanal medicament, while in the control group tosylchloramide sodium irrigating and calcium hydroxide disinfecting root canals were adopted. Microbiological sampling was performed before treatment, after instrumentation, and after intracanal medication. The frequency of positive culture and CFU of each culture were evaluated by ANOVA. RESULTS: The frequency of positive culture was dropped from 73.3% to 46.7% after instrumentation and to 13.3% after medication in the experimental group, while in the control group the frequency was dropped from 73.3% to 20.0% and 26.7% after medication (P=0.9721). CFU was dropped from 1462.9 to 27.9 after instrumentation and 15.7 after medication, while in the control group CFU was dropped from 1402.8 to 14.0 and 45.1 after medication (P=0.688). CONCLUSIONS: Jinzhi Hanshuye had good antibacterial effects on anaerobics of infected root canals.


Assuntos
Antibacterianos/farmacologia , Cavidade Pulpar/efeitos dos fármacos , Irrigantes do Canal Radicular/farmacologia , Hidróxido de Cálcio , Humanos
7.
Hua Xi Kou Qiang Yi Xue Za Zhi ; 24(3): 221-4, 2006 Jun.
Artigo em Zh | MEDLINE | ID: mdl-16845954

RESUMO

OBJECTIVE: To investigae the function of the glass colorant on the color of the machinable infiltrated ceramics(MIC). METHODS: Five kinds of glass with different colorant were infiltrated through the aluminous matrix by heating the components to 1 100 degrees C for 2 hours. The specimens surface was polished, and their thickness was 0.5 mm. RESULTS: The refractive index of the MIC infiltration glass was 1.59691 (587.6 nm, nd) . The most different parameter of the MIC color were L*, then a*, and b* had little difference . The parameters of the color space of MIC were: L*(64.55-71.46), a*(3.35-7.38), b*(10.00-12.41), Ca*b*(11.38-13.95), ha*b*(54.07-73.00). These were almost close to the color parameters of Vita In-ceram. CONCLUSION: This experiment proved that the glass colorant was changed the MIC color parameters, and the main function was on L*, then a*. The ceramic color was up to the requirement of clinic.


Assuntos
Cerâmica , Vidro , Óxido de Alumínio , Cor , Materiais Dentários , Porcelana Dentária , Humanos
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