Biomechanical effects of clear aligner with different shape design at extraction space area during anterior teeth retraction.

OBJECTIVE: This study aimed to investigate the biomechanical effects of clear aligner (CA) with different shape designs at extraction space (CAES) area during space closing. MATERIALS AND METHODS: A finite-element method (FEM) model of mandibular dentition, periodontal ligaments, attachments, and corresponding CA was established. The connecting rod design of CAES was modelled for the control group. Eight test groups with different heights of CAES from -4 mm to +4 mm were designed. Tooth displacement tendencies were calculated. The maximum principal stress in PDLs, teeth, and CAs was analysed. Both global coordinate system and local coordinate system were also used to evaluate individual tooth movements. RESULTS: Across all groups, stresses concentrated on the lingual outer surface of CAESs. For the lowered CAES groups, both the stress value and the stress distribution area at CAESs were increased. The lowered CAES groups showed reduced movement in anterior teeth and less tipping tendency of the canines. CONCLUSION: The shape of CAES has a biomechanical impact on anterior teeth movement and should be considered in aligner design. The results suggest that increasing the height of CAES can enhance anterior teeth retraction, while lowered CAES may facilitate controlled root movement. Changes in the shape of CAES represent a potential direction for biomechanical improvement of clear aligner in extraction cases and are worth exploring.

[Soft and hard tissue changes of hyperdivergent class â ¡ patients before and after orthodontic extraction treatment].

OBJECTIVE: To investigate the hard and soft tissue changing trend and contributing factors of skeletal class Ⅱ hyperdivergent patients before and after orthodontic camouflage treatment by analyzing the cephalogram and the three dimensional (3D) facial scan data. METHODS: Eighteen skeletal class Ⅱ hyperdivergent adult female patients who finished camouflage orthodontic treatment were selected. Skeletal and dental measurements were carried out with the cephalometric analysis before and after the treatment. 3D facial data before and after orthodontic treatment were acquired and the anatomical landmarks were set after the repositioning and superimposition process. Hard tissue measurement included 17 mea-surement indicators (sella-nasion-subspinale angle, sella-nasion-supramental angle, subspinale-nasion-supramental angle, facial angle, angle of convexity, Frankfort horizontal plane-mandibular plane angle (FH-MP), Y axis angle, sella-nasion plane-mandibular plane angle (MP-SN), pogonion-nasion-supramental distance, upper incisor-nasion-subspinale distance, upper incisor to sella-nasion, lower incisor-nasion-supramental distance, lower incisor-nasion-supramental angle, upper incisor to lower incisor, upper incisor to sella-nasion, lower incisor-mandibular plane angle, and Z angle), and the changes before and after treatment were measured for 11 of them. Twenty soft tissue landmarks (left/right cheekbone, left/right chelion, left/right crista philtra, soft tissue gnathion, left/right gonion, glabella, labrale infe-rius, labrale superius, soft tissue menton, left/right mid-mandibular border, soft tissue pogonion, stomion superius, sublabial, subnasale, and supralabial) and 9 soft tissue indicators (lower lip height, facial convexity, lower vermilion height, mandibular contour, nasolabial angle, philtral length, philtral width, upper lip height, and upper vermilion height) were measured and recorded for treatment changes. Linear-regression analysis and correlation analysis were carried out for analyzing the relationship between hard and soft tissue changes before and after the treatment. RESULTS: Significant differences were noticed for 18 out of the 20 cephalometric measurements and facial measurements before and after the treatment (P < 0.05), which mainly represented the sagittal retraction of lip area after the treatment. Significant vertical displacements were revealed for soft tissue menton after treatment [(1.88±2.61) mm, P < 0.05]. Significant sagittal displacements were revealed for left/right cheilion [(-2.95±1.9) mm, (-2.90±1.92) mm], labrale inferius[(-4.94±1.95) mm], labrale superius[(-3.25±1.44) mm], sublabial [(-3.10±3.5) mm], and subnasale [(-1.23±1.06) mm] after treatment (P < 0.05). An average of 4.10°±2.57° increasement was noticed for Z angle after treatment. High correlation (r>0.7) was noticed for the displacement of menton after treatment with FH-MP, with the rate of -0.183 :1, and MP-SN, with the rate of -0.157 :1. Moderate correlations (0.7≥r>0.4) were noticed for the other measurements with correlations (P < 0.05). CONCLUSION: A certain extent of facial improvements could be achieved with orthodontic camouflage treatment for skeletal class Ⅱ hyperdivergent patients, which were mostly represented by the improvement of sagittal relationship of nose, lips, and chin. Certain correlations were noticed for the hard and soft tissue changes.

A quantitative analysis of facial changes after orthodontic treatment with vertical control in patients with idiopathic condylar resorption.

OBJECTIVE: This study aimed to investigate temporomandibular joint (TMJ) stability and three-dimensional (3D) facial changes in class II hyperdivergent patients with stable idiopathic condylar resorption (ICR) after orthodontic camouflage treatment with vertical control by using temporary anchorage devises (TADs). METHODS: Nineteen skeletal class II hyperdivergent patients who were diagnosed with stable ICR underwent bicuspid extraction orthodontic treatment with vertical control via TADs were enrolled. TMJ was evaluated with the cone beam computerized tomography (CBCT) and clinical records before and after treatment. Changes in dental and skeletal parameters were evaluated with cephalometric and dental cast measurements. The 3D morphable model (3DMM) method was performed with the MeshMonk toolbox for the 3D facial analysis. After the reposition and landmark setting process, 3D facial heatmaps were used to illustrate facial changes, and the 3D deviations of landmarks were calculated. RESULTS: Both the imaging evaluation and clinical examination proved that TMJs remained stable after treatment. The retrusion of the upper and lower incisors reached 6.63 ± 0.79 mm and 3.78 ± 1.49 mm. The intrusion of the upper first molar reached 2.65 ± 0.75 mm, with a 2.27 ± 0.82° counterclockwise rotation of the mandibular plane. An upward shift of the soft tissue pogonion (2.34 ± 2.03 mm) and protrusion of Po-NB (0.82 ± 0.70 mm) was gained. Larger intrusion was found in the lower lip (3.29 ± 0.80 mm) than in the upper lip (2.20 ± 0.69 mm). CONCLUSION: Camouflage orthodontic treatment with TAD for vertical control is acceptable for skeletal class II hyperdivergent patients with ICR, which can improve the facial profile.

3D-printed titanium surgical guides for extraction of horizontally impacted lower third molars.

OBJECTIVES: This prospective study introduced a digitally designed sectioning guide and evaluated its feasibility for the extraction of horizontally impacted lower third molars. MATERIALS AND METHODS: This study included 38 horizontally impacted lower third molars, randomly divided into experimental and control groups. The teeth were extracted using a 3D-printed titanium surgical guide in the experimental group; free-hand extractions were performed in the control group. The surgical duration, tooth sectioning duration, cortical bone perforation, and postoperative complications, including pain, swelling, trismus, dry socket, infection, and hemorrhage, were evaluated. RESULTS: Although not statistically significant, guided surgery tended to reduce the number of tooth sectioning steps compared to free-hand extractions. There were no cases of cortical bone perforation in the experimental group. Although the surgical duration was greater in the experimental group (p < 0.05), there were no differences in postoperative pain, swelling, and trismus. There were no cases of postoperative infection and hemorrhage in either group. CONCLUSIONS: 3D-printed titanium surgical guides had superior accuracy and safety compared to free-hand surgery. Further studies with larger sample sizes are required to verify these findings. CLINICAL RELEVANCE: The template improved the safety of tooth sectioning during impacted lower third molar surgery and resulted in a more predictable extraction. The narrow sectioning groove could fit comfortably with hypertrophic soft tissues in the posterior mandible.

Optimization of the dimension of computer numerical control-milled polyetheretherketone clasps: An in vitro evaluation of accuracy.

STATEMENT OF PROBLEM: The accuracy and optimal dimensions of computer numerical control (CNC)-milled polyetheretherketone (PEEK) removable partial denture (RPD) clasps are unclear. PURPOSE: The purpose of this in vitro study was to investigate the trueness and precision of CNC-milled PEEK clasps with different thicknesses and lengths. MATERIAL AND METHODS: Ladder-shaped specimens of 2 thicknesses with 5 lengths of clasps were designed and milled with PEEK and commercially pure titanium (CP Ti) (n=6). All milled specimens were scanned and superimposed onto the design data. Three-dimensional and 2-dimensional deviation analyses were carried out to evaluate the trueness of milled PEEK clasps. The scanning data of each group were superimposed pairwise, and the 3-dimensional deviations were analyzed to evaluate the precision. Nonparametric tests, ANOVA, the Pearson correlation, and univariate linear regression were used for statistical analysis (α=.05). RESULTS: The deviation of trueness of the PEEK clasps (0.047 to 0.164 mm) was higher than that of the CP Ti clasps (0.037 to 0.060 mm) (P<.001). Increasing the length of the clasps increased the deviations (P<.001). Deviation in the 2 thicknesses was not significantly different (P=.210). The correlation coefficients of 1.0-mm-thick and 1.5-mm-thick PEEK and CP Ti clasps were 0.843, 0.794, 0.638, and 0.405. The positive correlation coefficients of PEEK were higher than those of CP Ti and those of 1.0-mm-thick clasps was higher than those of 1.5-mm-thick clasps. The deviations were evenly distributed in the 9-mm length of the clasp for CP Ti and in the 6-mm length of the clasp for PEEK. Beyond these lengths, deviations increased with increased length. The increasing amplitude of CP Ti was smaller than that of the PEEK group, and that of the 1.5-mm-thick clasp was smaller than that of the1.0-mm-thick clasp. The measured range of precision of PEEK clasps was 0.079 to 0.152 mm, while that of CP Ti clasps was 0.036 to 0.096 mm. CP Ti clasps tended to have better precision than PEEK clasps, except for the 1.0-mm-thick clasps with a length greater than 9 mm and the 1.5-mm-thick clasp with a 12-mm length. The correlation of the clasp length with precision showed that the lengths of 1.0-mm-thick clasps strongly influenced precision (PEEK, P=.020; CP Ti, P<.001); this correlation decreased sharply when the thickness of clasps was 1.5 mm (PEEK, P=.199; CP Ti, P=.107). CONCLUSIONS: Greater elasticity increased the deviations of milled clasps. The increased thickness helped the clasp remain stable during the milling process. The 1.5-mm-thick PEEK clasps in the 3-mm and 6-mm lengths were the optimal design tested.

The accuracy of a three-dimensional face model reconstructing method based on conventional clinical two-dimensional photos.

BACKGROUND: This study aims to investigate the accuracy of a three-dimensional (3D) face reconstruction method based on conventional clinical two-dimensional (2D) photos. METHODS: Twenty-three patients were included, and Character Creator v3.2 software with the Headshot v1.0 plugin was used for 3D face model reconstruction. Various facial landmarks were finely adjusted manually to refine the models. After preprocessing and repositioning, 3D deviation analysis was performed. The accuracy of the landmarks in different dimensions was determined, and twelve facial soft tissue measurements were compared to validate the clinical potential of the method. RESULT: The reconstructed 3D face models showed good facial morphology with fine texture. The average root mean square errors between face scan models and reconstructed models at perioral area (1.26 ± 0.24 mm, 95%CI: 1.15-1.37 mm) were significantly smaller than the entire facial area (1.77 ± 0.23 mm, 95%CI:1.67-1.88 mm), P < 0.01. The deviation of menton of soft tissue was significantly larger than pronasale (P < 0.01). The deviations of all landmarks in the Y-direction were significantly larger than those in the other 2 dimensions (Y > Z > X, P < 0.01). A significant difference (P < 0.05) of approximately 1.5 mm was found for facial height. Significant differences (P < 0.05) were also identified in the remaining 6 soft tissue measurements, with average deviations no greater than 0.5 mm (linear measurement) or 1.2° (angular measurements). CONCLUSION: A 3D face modeling method based on 2D face photos was revealed and validated. The reconstruction accuracy of this method is clinically acceptable for orthodontic measurement purposes, but narrow clinical indications and labor-intensive operations remain problems.

Digital Workflow for a Scleroderma Patient with Microstomia: A Clinical Report.

Making impressions in patients with microstomia is often rather problematic due to their restricted mouth opening. Herein, this report describes a novel digital workflow for making impressions with computer-aided design and computer-aided manufacturing (CAD/CAM) custom sectional trays for a 58-year-old female patient with scleroderma and microstomia. CAD/CAM custom sectional trays were made based on digital dentition models from another case with similar arch scale. After the sectional impressions were obtained, the sectional casts were scanned and digitally aligned to form the final dentition models. The removable partial dentures were designed on the final digital models and printed using a 3D printer. This procedure was executed with a successful prosthetic outcome that included good fit and acceptable esthetics. The patient also reported a high level of satisfaction.

Expansion rebound deformation of clear aligners and its biomechanical influence: a three-dimensional morphologic analysis and finite element analysis study.

OBJECTIVES: To determine the expansion rebound deformation (ERD) of clear aligners (CAs) and its biomechanical influence. MATERIALS AND METHODS: A four-premolar extraction treatment plan was carried out for a patient with 2 CA companies. Thirty-six digitally scanned clear aligners with the corresponding 36 virtually constructed "ideal" aligners were constructed. The arch width and length between pairs of reference landmarks of the scanned CAs and corresponding dentition models were measured. Cone-beam computed tomography data and digital dental models were used for three-dimensional (3D) finite element analysis (FEA) modeling. Thirty-six scanned CA models with the corresponding 36 ideal CA models were constructed. One-way analysis of variance was used to determine the differences among deviation values at tooth level, and paired t-test was used to compare the displacements of teeth between the two group of CAs. RESULTS: All CAs were wider and shorter than the digital model from which they were constructed. In the scanned CA model group, significant stress was observed in the buccolingual area of the periodontal ligament on posterior teeth, and the corresponding displacements of teeth were also noted. Significantly larger coronal displacements were noted for the lateral incisor, the canine, the second premolar, and the first molar in the scanned CA group (P < .05). CONCLUSIONS: The general trend of ERD of thermoformed CAs was shown. This deformation may cause unforeseen tooth movements and negatively affect treatment outcomes.

Orthodontic craniofacial pattern diagnosis: cephalometric geometry and machine learning.

Efficient and reliable diagnosis of craniofacial patterns is critical to orthodontic treatment. Although machine learning (ML) is time-saving and high-precision, prior knowledge should validate its reliability. This study proposed a craniofacial ML diagnostic workflow base on a cephalometric geometric model through clinical verification. A cephalometric geometric model was established to determine the landmark location by analyzing 408 X-ray lateral cephalograms. Through geometric information and feature engineering, nine supervised ML algorithms were conducted for sagittal and vertical skeleton patterns. After dimension reduction, plane decision boundary and landmark contribution contours were depicted to demonstrate the diagnostic consistency and the consistency with clinical norms. As a result, multi-layer perceptron achieved 97.56% accuracy for sagittal, while linear support vector machine reached 90.24% for the vertical. Sagittal diagnoses showed average superiority (91.60 ± 5.43)% over the vertical (82.25 ± 6.37)%, where discriminative algorithms exhibited more steady performance (93.20 ± 3.29)% than the generative (85.98 ± 9.48)%. Further, the Kruskal-Wallis H test was carried out to explore statistical differences in diagnoses. Though sagittal patterns had no statistical difference in diagnostic accuracy, the vertical showed significance. All aspects of the tests indicated that the proposed craniofacial ML workflow was highly consistent with clinical norms and could supplement practical diagnosis.

The effect of maxillary molar distalization with clear aligner: a 4D finite-element study with staging simulation.

INTRODUCTION: Long-term simulation of tooth movement is crucial for clear aligner (CA) treatment. This study aimed to investigate the effect of maxillary molar distalization with CA via an automatic staging simulation. METHOD: A finite-element method (FEM) model of maxillary dentition, periodontal ligaments, attachments, and corresponding CA was established, and a prescribed 2-mm distalization with 0.1 mm each step of the second molar was simulated. The long-term tooth movement under orthodontic force was simulated with an iterative computation method. The morphologic changes of CA during staging were simulated with the thermal expansion method. RESULTS: Twenty steps of molar distalization were simulated. Significant distal tilting of the second molar was revealed, along with the proclination of anterior teeth, which caused the 'reversed bow effect'. For the second molar, 4.63°distal tilting at the 20th step was revealed. The intrusion of the incisors and the second molar were 0.43 mm, 0.39 mm, and 0.45 mm, respectively, at step 20. All the anterior teeth showed a proclination of approximately 1.41°-2.01° at the 20th step. The expression rate of the designed distalization of the second molar was relatively low (approximately 68%) compared to the high efficacy of interdental space opening between molars with CA (approximately 89%). CONCLUSION: A novel method of simulating long-term molar distalization with CA with FEM was developed. The FEM results suggested distal tilting of the second molar and the proclination of anterior teeth during the molar distalization.

Effects of orthodontic camouflage treatment vs orthodontic-orthognathic surgical treatment on condylar stability in Class II hyperdivergent patients with severe temporomandibular joint osteoarthrosis: a retrospective observational study.

OBJECTIVES: To investigate the differences in profile changes and stability of the condyles between orthodontic camouflage treatment assisted by vertical control and that accomplished via orthognathic surgery in Class II hyperdivergent patients with TMJ osteoarthrosis (TMJOA). MATERIALS AND METHODS: This study included 27 Class II hyperdivergent TMJOA patients (54 condyles) who received orthodontic camouflage treatment (13 patients) or orthognathic surgery (14 patients) Cone-beam computerized tomography (CBCT) scans were taken before treatment (T1) and 1 year after treatment (T2). Cephalometric and TMJ measurement analyses were conducted to evaluate the change in profile and condyles from T1 to T2 using independent samples t-test and paired t-test. Three-dimensional (3D) deviation analysis was also performed to evaluate the stability of condyles from T1 to T2. RESULTS: Both groups showed significant profile improvement from T1 to T2. The changes in Z angle and ANB angle were larger in the surgical group than in the orthodontic group. Condylar width, length, and height remained stable after treatment in the orthodontic group (P > .05), while they reduced by 0.67 ± 0.85 mm, 1.14 ± 1.10 mm, and 1.07 ± 1.34 mm, respectively, in the surgical group (P < .05). Superior, posterior, medial, and lateral joint spaces were significantly reduced in the orthodontic group (P < .05). 3D deviations intuitively showed that condylar bone in the orthodontic group was more stable than that in the surgical group. CONCLUSIONS: For Class II hyperdivergent patients with severe TMJOA, orthodontic camouflage treatment with vertical control can effectively maintain the stability of condyles while significantly improving the profile. Surgical treatment yields a better profile but may increase the risk of condyle resorption.

Effect of Different Anchorage Reinforcement Methods on Long-Term Maxillary Whole Arch Distalization with Clear Aligner: A 4D Finite Element Study with Staging Simulation.

The objective of this study was to examine how various anchorage methods impact long-term maxillary whole arch distalization using clear aligners (CAs) through an automated staging simulation. Three different anchorage reinforcement methods, namely, Class II elastics, buccal temporary anchorage device (TAD), and palatal TAD, were designed. Orthodontic tooth movement induced by orthodontic forces was simulated using an iterative computation method. Additionally, the automatic adjustment of the CA was simulated through the application of the thermal expansion method. The results indicated that the palatal TAD group had the largest retraction of incisors, followed by the buccal TAD group and the Class II elastic group, while the least was in the control group. The largest distal displacements and efficiency of molar distalization for the first and the second molars were noticed in the palatal TAD group. Arch width increased at the molar and premolar levels in all groups. The FEM results suggested palatal TAD had the best performance considering anterior teeth anchorage maintenance, both sagittally and vertically. However, attention should be paid to the possible increasement of arch width.

Audit to assess the quality of 916 prosthetic prescriptions of removable partial dentures.

OBJECTIVES: The objectives of this study were to assess the quality of prosthetic prescriptions of removable partial dentures (RPDs) and to analyze the current situation of the communication and information delivery between clinicians and technicians. METHODS: All RPD prosthetic prescriptions received by a major dental laboratory in 4 weeks were involved in a quality audit, and the prescriptions were divided into three groups in accordance with the grades of clients. The filling of prosthetic prescriptions was recorded. The items in the prescriptions for audit included the general information of the patient, the general information of the clinician, the design diagram information, other detailed information, and the return date. The prescriptions were categorized into four levels on the basis of their quality by two quality inspectors who have been working for more than 10 years. RESULTS: A total of 916 prescriptions were collected and assessed. The names in the general information of the patient and the clinician were filled out best, both at the rate of 97.6% (n=894). The return date was filled out worst, only at the rate of 6.4% (n=59). Of those prescriptions, 86.8% (n=795) exhibited inadequate design diagram information. The results of the quality assessment demonstrated that 74.2% of prescriptions were assessed as noncompliant ones and failed to meet the acceptable clinical quality standard. CONCLUSIONS: At present, the overall quality of RPD prosthetic prescriptions is poor. The responsibilities of clinicians and technicians are unclear, and the communication between them is not ideal.

Casein phosphopeptide-amorphous calcium phosphate modified glass ionomer cement attenuates demineralization and modulates biofilm composition in dental caries.

The study investigated the effects of the modified conventional glass ionomer cement (GIC) incorporated with casein phosphopeptide-amorphous calcium phosphate (CPP-ACP) on biofilm composition of dental caries. Shear bond strength, durability tests, adhesive remnant index (ARI) and scanning electron microscope were used to measure the physical properties. Microhardness and ions release were determined to evaluate anti-demineralization effects; growth of the biofilm and its composition were assessed using MTT assay and Q-PCR assay. All experimental groups exhibited a significant stimulation of ions release, and reduced attenuation of microhardness. Nearly 39% reduction in the bacterial biofilm was observed with 5% CPP-ACP group. The regulation ability is mainly manifested in the inhibition of S. mutans and promotion of S. gordonii. The modified GICs by exhibiting anti-demineralization effects potentially lead to a reduction in the cariogenicity of plaque and can serve as a putative promising remineralization system with both enhanced antimicrobial and remineralization properties.

[A technique to design the framework of removable partial denture by multi-stage expert system].

This study aims to apply a new expert system to design removable partial denture (RPD) framework. The RPD design is completed in three steps, namely, "selecting missing teeth", "selecting abutment condition", and "selecting personalized clasp". The system can help auxiliary dentists develop personalized treatment plans to reduce their clinical workload. It can also generate a dental preparation guideline for clinical preparation, which can prevent tooth preparation mistakes. By generating the standard electronic drawings of the framework design, the system can reduce the inconvenience caused by manual drawing, thereby facilitating dentist-technician communication and reducing the rate of remade.

Effectiveness of surface texture simulation of fixed dental prostheses by curvature analysis.

OBJECTIVE: The current design methods for the surface texture of prostheses are unsatisfactory: the line-drawing method relies heavily on the subjective experience of technicians, and the powder-coating method requires high costs. A new innovative method is proposed: curvature-analysis with reverse engineering. The objective was to compare operation times and esthetic parameters in generating surface textures among the three methods. METHOD AND MATERIALS: Twenty-seven patients with maxillary central incisor fixed dental prostheses were randomly divided into three groups, and prostheses were built by three technicians using line-drawing, powder-coating, or curvature-analysis methods, respectively. Porcelain grinding times were recorded. The final prostheses were analyzed regarding the three-dimensional deviation from the control group that used the contralateral tooth. A senior technician and clinician made a single-blind evaluation of the prostheses' surface texture. RESULTS: In the curvature-analysis method, large, medium, and small curvatures effectively showed an intrinsic labial surface, the developmental groove, and other surface morphology structures, respectively. Operation times in the line-drawing, powder-coating, and curvature-analysis methods were 19.51 ± 0.95, 16.87 ± 1.30, and 12.41 ± 0.94 minutes, respectively, with statistically significant differences among the three methods; evaluation scores were statistically significantly different between the line-drawing and curvature-analysis methods. The three-dimensional deviation root mean square values were 0.451 ± 0.083, 0.396 ± 0.029, and 0.295 ± 0.080 mm, respectively, indicating curvature analysis had the smallest three-dimensional deviation. CONCLUSIONS: Curvature analysis helps manufacture the surface texture accurately with enhanced efficiency, improving esthetics and reducing operation time and material waste.

A three-dimensional finite element analysis of mechanical function for 4 removable partial denture designs with 3 framework materials: CoCr, Ti-6Al-4V alloy and PEEK.

Polyetheretherketone (PEEK) is a new material used for the frameworks of removable partial dentures (RPD). The questions whether the PEEK framework has similar stress distribution on oral tissue and displacement under masticatory forces as titanium alloy (Ti-6Al-4V) or cobalt-chromium alloy (CoCr) remain unclear and worth exploring. A patient's intraoral data were obtained via CBCT and master model scan. Four RPDs were designed by 3Shape dental system, and the models were processed by three-dimensional finite element analysis. Among three materials tested, PEEK has the lowest maximum von Mises stress (VMS) on periodontal ligament (PDL), the greatest maximum VMS on mucosa, the maximum displacement on free-end of framework, and the lowest maximum VMS on framework. Results suggested that PEEK framework has a good protective effect on PDL, suggesting applications for patients with poor periodontal conditions. However, the maximum displacement of the free-end under masticatory force is not conducive for denture stability, along with large stress on the mucosa indicate that PEEK is unsuitable for patients with more loss of posterior teeth with free-end edentulism.