RESUMO
PURPOSE: This clinical and histological study evaluated the healing of extraction sockets after implantation of a biphasic calcium sulfate (CS) alone or in combination with a gamma-radiated human mineralized allograft. MATERIALS AND METHODS: Ten healthy adult patients participated in the study. A minimum of 2 teeth, per patient, extracted for different reasons were evaluated. Each socket was randomly filled to the crest with either (a) a biphasic CS or (b) large particulate gamma-radiated human mineralized allograft in combination with a biphasic CS. RESULTS: No complications during reentry of the socket site during bone core retrieval, such as inflammation/immunogenic response, were observed. Histological findings showed a mean new bone (NB) of 33% for sockets filled with biphasic CS and 31% for sockets filled with biphasic CS in combination with allograft material. There was no statistically significant difference in the percentage of NB and the presence of soft tissue between graft materials. CONCLUSION: Biphasic CS used alone or in combination with an allograft resulted in the same amount of NB formation in alveolar ridge preservation procedures.
Assuntos
Substitutos Ósseos , Alvéolo Dental/patologia , Adolescente , Adulto , Antibacterianos/administração & dosagem , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Extração Dentária , Adulto JovemRESUMO
There are over 100 modified bases that occur in RNA with the majority found in transfer RNA. It has been widely believed that the queuine modification is limited to four transfer RNA species in vivo. However, given the vast amount of the human genome (60-70%) that is transcribed into non-coding RNA (Mattick [10]), probing the presence of modified bases in these RNAs is of fundamental importance. The mechanism of incorporation of queuine, via transglycosylation, makes this uniquely poised to probe base modification in RNA. Results of incubations of Escherichia coli cell cultures with [(3)H] preQ(1) (a queuine precursor in eubacteria) clearly demonstrate preQ(1) incorporation into a number of RNA species of various sizes larger than transfer RNA. Specifically, significant levels of preQ(1) incorporation into ribosomal RNA are observed. The modification of other large RNAs was also observed. These results confirm that non-coding RNAs contain modified bases and lead to the supposition that these modifications are necessary to control non-coding RNA structure and function as has been shown for transfer RNA.
Assuntos
Escherichia coli/metabolismo , Guanina/análogos & derivados , Pirimidinonas/química , Pirróis/química , Processamento Pós-Transcricional do RNA , RNA Bacteriano/química , Resinas Acrílicas/química , Eletroforese em Gel de Ágar , Guanina/análise , Marcação por Isótopo , RNA de Transferência/química , Trítio/químicaRESUMO
La aplicación de los computadores en la odontología ha sido poco explorada en el campo de la capacitación y la educación odontológica. La nueva era de la capacitación y de la educación asistida por la informática se basa en el desarrllo de programas realizados por multimedia como medio auxiliar.El proyecto que realizamos pretende aplicar un método lógico,científico y concreto de manera objetiva,mediante la utilización de un programa computarizado de Sofware,como ayuda al estudiante de pregrado,en la capacitación y entendimiento de los desórdenes craneomandibulares,en su definición,etiología,diagnóstico clínico,signos y síntomas,medios diagnósticos y plan de tratamiento.