Use of Calcium Phosphate Cement for Repairing Bone Defects: Histomorphometric and Immunohistochemical Analyses.

This study aimed to assess the repair of surgically created bone defects filled with blood clot, autogenous bone, and calcium phosphate cement, by histomorphometric and immunohistochemical analyses. Ten adult male rabbits were used. Three bone defects were prepared with an 8-mm diameter trephine bur in the parietal region of each animal and filled with blood clot (Group BC), autogenous bone (Group AB), and calcium phosphate bone cement (Group CPC). The animals were euthanized at 40 and 90 postoperative days. The sections were subjected to histomorphometric analysis of the new bone formed inside the calvarial defects and immunohistochemical staining to determine the expression of osteocalcin (OC), osteopontin (OP), and tartrate-resistant acid phosphatase (TRAP) proteins. Histomorphometric data were analyzed statistically by analysis of variance and Tukey's post hoc test at 5% significance level. In the results at 40 and 90 days, Group AB differed significantly from Group CPC regarding the area of newly formed bone. The immunohistochemical analysis revealed expression of OP, OC, and TRAP proteins in all groups. Group AB showed prevalence of OC and OP, and lower TRAP expression. Therefore, the calcium phosphate bone cement assessed in the present study did not accelerate the protein expression dynamics during bone healing, compared with the autogenous group.

Rehabilitation using immediate loading in patients with partial resection of the jaw

ABSTRACT: Ameloblastoma is a rare tumor that affects the maxillomandibular region. Surgical resection is often indicated, and oral rehabilitation becomes a challenge. This study aims to report on the mandibular rehabilitation with implant supported prosthesis using immediate loading with subsequent resection. A patient with a confirmed diagnosis of multicystic ameloblastoma in the left jaw underwent a partial resection of the mandible and a reconstruction with a titanium plate. After 2 years of follow-up with clinical examinations and imaging testing and with no signs of recurrence, the patient underwent the technique of immediate load implants, rehabilitating the mandible with an implant supported fixed prosthesis and the maxilla with a conventional complete denture. During the seven years of follow-up with the patient, there was no sign of recurrence of ameloblastoma. The rehabilitation with oral implants under immediate loading demonstrated to be successful, and the cemented cylinder technique used in this study coupled with passivity showed a favorable prognosis for the longevity of implants.

Fratura de mandíbula após a instalação de implantes - relato de caso / Mandibular fracture after implants instalation - case report

As fraturas de mandíbulas após a instalação de implante são pouco descritas na literatura e, geralmente, estão relacionadas ao enfraquecimento ósseo devido à baixa densidade e vascularização desse osso em idosos. Este relato de caso clínico associado à revisão de literatura tem o objetivo de apresentar um caso de fratura de mandíbula tardia após a instalação de implantes e aplicação de carga imediata. No presente caso, uma paciente de 86 anos de idade, do gênero feminino, foi submetida à instalação de 4 implantes dentários, entre os forames mentuais, seguida de prótese do tipo protocolo inferior com carga imediata. Passado 3 semanas do procedimento cirúrgico foi diagnosticado a fratura incompleta do ângulo mandibular direito. O tratamento dessa paciente foi conservador com orientação dietética, prescrição medicamentosa e acompanhamento por 60 dias. Após o período de 180 dias foi constatado o reparo completo da região. Com base nesse caso clínico foi possível concluir que o tratamento conservador é uma alternativa viável para o tratamento de fratura mandibular tardia após a instalação de implantes dentários...

The atrophic mandible fractures after the installation of the implant are widely described in the literature and generally relate to a weakening due to low bone density and that bone vascularity in the elderly. This case report associated clinical literature review aims to present a case of atrophic mandible fractures caused after installation of dental implants. In this case, a 86 year-old female, underwent installation of 4 dental implants, among mentuals foramen, then the type of prosthesis with immediate loading protocol below. Last three weeks of the surgical procedure was diagnosed incomplete fracture of the right mandibular angle. The treatment of this patient was conservatively with dietary counseling, prescriptions and follow- -up for 60 days. After of period 180 days it was found complete repair of the region. Based on this case study it was con-cluded that conservative treatment is a viable alternative for the treatment of atrophic mandibular fracture after installation of dental implants...