[Conditionally pathogenic microorganisms in patients with bisphosphonate jaw osteonecrosis].

The objective of the study was to define treatment strategy in cases of facial bones bisphosphonate induced osteonecrosis based on the study of the role of conditionally pathogenic oral microorganisms. Three typical clinical cases of bisphosphonate osteonecrosis of the facial bones were analyzed and 15 conditionally pathogenic oral microorganisms were identified in these patients using real-time PCR in saliva, wound and bone samples. A comparative analysis was carried out with purulent-inflammatory diseases of maxillofacial area. The study results proved an important role of conditionally pathogenic microorganisms of the oral cavity in the development of osteonecrosis of the facial bones. Wide range of bacterial species was identified in osteonecrosis of the facial bones patients. While bone tissue is most exposed to microbial communities, surgical treatment results in effective rehabilitation for a long period.

[Surgical treatment of patients with drug abuse and mandible necrosis].

The article describes clinical and radiological classification of osteonecrosis of the mandible in patients with drug dependence, surgical options presented on the basis of classification proposed. Clinical case of simultaneous application of individual plate of nikelid titanium in patient with osteonecrosis of the mandible is presented.

[Nickelid titanium mesh for orbital floor reconstruction].

The treatment plan for patients with mid-face fractures was presented in this article. In maxillofacial department of the I.M. Sechenov First Moscow State Medical University we used nickelid titanium mesh for reconstruction of the orbital floor. The clinical case with good result of treatment was presented here.

[Methods of tissue engineering of bone tissue in maxillofacial surgery].

For the last decade many experimental and clinical data about the study and application of regenerative medicine methods in the maxillofacial surgery were accumulated. For better bone regeneration mesenchymal stem cells are often used. Considering the general wariness of researchers in some aspects of cell therapy, methods of study of mesenchymal stem cells and the technologies of its clinical application are constantly being upgraded. This review will consider methods of tissue engineering used to regenerate bone tissue defects in maxillofacial surgery.

[Treatment tactics by mandibular fractures in teeth-bearing area].

The aim of this study was to develop treatment plan for mandibular fractures in tееth bearing area in order to decrease complication rate. We have developed indication and contraindication for endonontic procedures and the extraction of the tooth in the fracture line. It was concluded that the overall complication rate was low and can further be reduced.

[Superelastic constructions in surgical treatment of mandible condylar process fractures with full medial head of mandible dislocation].

Between 2007 and 2009 15 patients with medially dislocated head fractures of condylar process were surgically treated in Sechenov Moscow Medical Academy. All patients were surgically treated with open reduction--mandibular rami osteotomy, replantation of condylar head and osteosynthesis with nikelide titanium gages. Modern surgical technologies implementing nikelide titanium gages for osteosynthesis simplifies operation technique, decreased surgical trauma and increased overall treatment quality of such patients.

[Use of constructions from porous titanium nikelide for treatment of fractures of lower wall of eye-socket].

Surgical reconstructive treatment was done in 45 patients with fractures of lower wall of eye-socket in the clinic of maxillofacial surgery of MMA (named after I.M. Sechenov) during the period from July 2007 to July 2008. All fractures were cured with constructions from titanium nikelide. Use of implants from porous titanium nikelide let to shorten the operation time, to decrease the risk of infection joining, to prevent fibrous capsule formation along implant periphery that was essential in prevention of scarring and enophthalmia.

[The use of titanium nickelide devices in treating fractures of the zygomatico-orbital complex]. / Primenenie ustroistv iz nikelida titana pri lechenii perelomov skuloglaznichnogo kompleksa.

The authors analyze the results of surgical treatment of 78 patients with zygomatico-orbital injuries. Mini-cramps and mini-plates of titanium nickelide with thermomechanical memory were employed for fracture fixation. Surgical strategy based on osteosynthesis with the use of such devices provides a reliable fixation of bone fragments and makes the operation less traumatic.

[Results of treatment of chronic generalized periodontitis with a dispersed biomaterial Alloplant]. / Rezul'taty lecheniia khronicheskogo generalizovannogo parodontita s ispol'zovaniem dispergirovannogo biomateriala Alloplant.

There is a method of treatment of generalized chronic periodontitis with using dispersing biomaterial Alloplant and immunological, histomorphological criteria of this estimation.

[The clinical and X-ray classification of osteonecrosis of the low jaw].

OBJECTIVE: To elaborate a clinical and X-ray classification of osteonecrosis of the low jaw in people with desomorphine or pervitin addiction. MATERIAL AND METHODS: Ninety-two patients with drug addiction who had undergone orthopantomography, direct frontal X-ray of the skull, and multislice computed tomography, followed by multiplanar and three-dimensional imaging reconstruction were examined. One hundred thirty four X-ray films and 74 computed tomographic images were analyzed. RESULTS: The authors proposed a clinical and X-ray classification of osteonecrosis of the low jaw in people with desomorphine or pervitin addiction and elaborated recommendations for surgical interventions on the basis of the developed classification. CONCLUSION: The developed clinical and X-ray classification and recommendations for surgical interventions may be used to treat osteonecroses of various etiology.