Detalhe da pesquisa
1.
Comparison between Nanoparticle Encapsulation and Surface Loading for Lysosomal Enzyme Replacement Therapy.
Int J Mol Sci
; 23(7)2022 Apr 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-35409394
2.
Enhanced Delivery and Effects of Acid Sphingomyelinase by ICAM-1-Targeted Nanocarriers in Type B Niemann-Pick Disease Mice.
Mol Ther
; 25(7): 1686-1696, 2017 07 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-28606376
3.
Biodegradable "Smart" Polyphosphazenes with Intrinsic Multifunctionality as Intracellular Protein Delivery Vehicles.
Biomacromolecules
; 18(6): 2000-2011, 2017 Jun 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-28525259
4.
How Carrier Size and Valency Modulate Receptor-Mediated Signaling: Understanding the Link between Binding and Endocytosis of ICAM-1-Targeted Carriers.
Biomacromolecules
; 17(10): 3127-3137, 2016 10 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-27585187
5.
Clathrin-mediated endocytosis is impaired in type A-B Niemann-Pick disease model cells and can be restored by ICAM-1-mediated enzyme replacement.
Mol Pharm
; 11(8): 2887-95, 2014 Aug 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-24949999
6.
Comparative binding, endocytosis, and biodistribution of antibodies and antibody-coated carriers for targeted delivery of lysosomal enzymes to ICAM-1 versus transferrin receptor.
J Inherit Metab Dis
; 36(3): 467-77, 2013 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-22968581
7.
Polymer-based drug delivery systems under investigation for enzyme replacement and other therapies of lysosomal storage disorders.
Adv Drug Deliv Rev
; 197: 114683, 2023 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-36657645
8.
Targeted Nanocarriers Co-Opting Pulmonary Intravascular Leukocytes for Drug Delivery to the Injured Brain.
ACS Nano
; 17(14): 13121-13136, 2023 07 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-37432926
9.
A fibrinogen-derived peptide provides intercellular adhesion molecule-1-specific targeting and intraendothelial transport of polymer nanocarriers in human cell cultures and mice.
J Pharmacol Exp Ther
; 340(3): 638-47, 2012 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-22160267
10.
Enhanced delivery of α-glucosidase for Pompe disease by ICAM-1-targeted nanocarriers: comparative performance of a strategy for three distinct lysosomal storage disorders.
Nanomedicine
; 8(5): 731-9, 2012 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-21906578
11.
Control of endothelial targeting and intracellular delivery of therapeutic enzymes by modulating the size and shape of ICAM-1-targeted carriers.
Mol Ther
; 16(8): 1450-8, 2008 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-18560419
12.
Combining vascular targeting and the local first pass provides 100-fold higher uptake of ICAM-1-targeted vs untargeted nanocarriers in the inflamed brain.
J Control Release
; 301: 54-61, 2019 05 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-30871995
13.
Delivery of acid sphingomyelinase in normal and niemann-pick disease mice using intercellular adhesion molecule-1-targeted polymer nanocarriers.
J Pharmacol Exp Ther
; 325(2): 400-8, 2008 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-18287213
14.
In vivo imaging of 64Cu-labeled polymer nanoparticles targeted to the lung endothelium.
J Nucl Med
; 49(1): 103-11, 2008 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-18077519
15.
Co-coating of receptor-targeted drug nanocarriers with anti-phagocytic moieties enhances specific tissue uptake versus non-specific phagocytic clearance.
Biomaterials
; 147: 14-25, 2017 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-28923682
16.
Flow shear stress differentially regulates endothelial uptake of nanocarriers targeted to distinct epitopes of PECAM-1.
J Control Release
; 210: 39-47, 2015 Jul 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-25966362
17.
Enhancing biodistribution of therapeutic enzymes in vivo by modulating surface coating and concentration of ICAM-1-targeted nanocarriers.
J Biomed Nanotechnol
; 10(2): 345-54, 2014 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-24738342
18.
In vivo performance of polymer nanocarriers dually-targeted to epitopes of the same or different receptors.
Biomaterials
; 34(13): 3459-66, 2013 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-23398883
19.
Biological functionalization of drug delivery carriers to bypass size restrictions of receptor-mediated endocytosis independently from receptor targeting.
ACS Nano
; 7(12): 10597-611, 2013 Dec 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-24237309
20.
Transport of nanocarriers across gastrointestinal epithelial cells by a new transcellular route induced by targeting ICAM-1.
J Control Release
; 163(1): 25-33, 2012 Oct 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-22698938