Detalhe da pesquisa
1.
Hydrophobicity Tuning of Cationic Polyaspartamide Derivatives for Enhanced Antisense Oligonucleotide Delivery.
Bioconjug Chem
; 35(2): 125-131, 2024 02 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-38290165
2.
Analysis of the sustained release ability of bevacizumab-loaded tetra-PEG gel.
Exp Eye Res
; 223: 109206, 2022 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-35921961
3.
Dynamic Stabilization of Unit Polyion Complexes Incorporating Small Interfering RNA by Fine-Tuning of Cationic Block Length in Two-Branched Poly(ethylene glycol)-b-poly(l-lysine).
Biomacromolecules
; 23(1): 388-397, 2022 01 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-34935361
4.
Installation of a Thermoswitchable Hydrophobic Domain into a Unimer Polyion Complex for Enhanced Cellular Uptake of siRNA.
Bioconjug Chem
; 31(5): 1320-1326, 2020 05 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-32352276
5.
Noncovalent Stabilization of Vesicular Polyion Complexes with Chemically Modified/Single-Stranded Oligonucleotides and PEG-b-guanidinylated Polypeptides for Intracavity Encapsulation of Effector Enzymes Aimed at Cooperative Gene Knockdown.
Biomacromolecules
; 21(10): 4365-4376, 2020 10 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-32924444
6.
Systemic Brain Delivery of Antisense Oligonucleotides across the Blood-Brain Barrier with a Glucose-Coated Polymeric Nanocarrier.
Angew Chem Int Ed Engl
; 59(21): 8173-8180, 2020 05 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-31995252
7.
Self-Assembly of siRNA/PEG- b-Catiomer at Integer Molar Ratio into 100 nm-Sized Vesicular Polyion Complexes (siRNAsomes) for RNAi and Codelivery of Cargo Macromolecules.
J Am Chem Soc
; 141(8): 3699-3709, 2019 02 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-30729777
8.
Tuned Density of Anti-Tissue Factor Antibody Fragment onto siRNA-Loaded Polyion Complex Micelles for Optimizing Targetability into Pancreatic Cancer Cells.
Biomacromolecules
; 19(6): 2320-2329, 2018 06 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-29767505
9.
An Ethylenediamine-based Switch to Render the Polyzwitterion Cationic at Tumorous pH for Effective Tumor Accumulation of Coated Nanomaterials.
Angew Chem Int Ed Engl
; 57(18): 5057-5061, 2018 04 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-29512262
10.
Polyplex Micelles with Phenylboronate/Gluconamide Cross-Linking in the Core Exerting Promoted Gene Transfection through Spatiotemporal Responsivity to Intracellular pH and ATP Concentration.
J Am Chem Soc
; 139(51): 18567-18575, 2017 12 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-29188718
11.
siRNA-Loaded Polyion Complex Micelle Decorated with Charge-Conversional Polymer Tuned to Undergo Stepwise Response to Intra-Tumoral and Intra-Endosomal pHs for Exerting Enhanced RNAi Efficacy.
Biomacromolecules
; 17(1): 246-55, 2016 Jan 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-26616636
12.
Recent Progress in the Endosomal Escape Mechanism and Chemical Structures of Polycations for Nucleic Acid Delivery.
Macromol Biosci
; 24(4): e2300366, 2024 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-38226723
13.
Molecular Weight-Dependent Diffusion, Biodistribution, and Clearance Behavior of Tetra-Armed Poly(ethylene glycol) Subcutaneously Injected into the Back of Mice.
ACS Macro Lett
; 12(4): 510-517, 2023 04 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-37012585
14.
In situ-formable, dynamic crosslinked poly(ethylene glycol) carrier for localized adeno-associated virus infection and reduced off-target effects.
Commun Biol
; 6(1): 508, 2023 05 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-37193797
15.
Bridging mRNA and Polycation Using RNA Oligonucleotide Derivatives Improves the Robustness of Polyplex Micelles for Efficient mRNA Delivery.
Adv Healthc Mater
; 11(9): e2102016, 2022 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-34913604
16.
Fine-tuning of polyaspartamide derivatives with alicyclic moieties for systemic mRNA delivery.
J Control Release
; 342: 148-156, 2022 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-34995697
17.
Star-Polymer-DNA Gels Showing Highly Predictable and Tunable Mechanical Responses.
Adv Mater
; 34(13): e2108818, 2022 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-35034389
18.
Size-tunable PEG-grafted copolymers as a polymeric nanoruler for passive targeting muscle tissues.
J Control Release
; 347: 607-614, 2022 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-35613686
19.
mRNA loading into ATP-responsive polyplex micelles with optimal density of phenylboronate ester crosslinking to balance robustness in the biological milieu and intracellular translational efficiency.
J Control Release
; 330: 317-328, 2021 02 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-33359053
20.
Structural tuning of oligonucleotides for enhanced blood circulation properties of unit polyion complexes prepared from two-branched poly(ethylene glycol)-block-poly(l-lysine).
J Control Release
; 330: 812-820, 2021 02 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-33417983