Comparison of Different Antibiotic Medications on Microorganisms: An Original Research.

Introduction: The onset and maintenance of disease can be significantly influenced by the colonization of the mouth cavity by pathogenic microorganisms or by an imbalance of the physiological microbiome. Hence, in the current study, various commonly used antibiotics have been tested for their antibacterial and antifungal activity. Materials and Methods: The current research was performed as an in vitro study. The commonly used antibiotics Augmentin (CV), Ceftriaxone-Cephalosporin (CF), and Linezolid were tested for the microorganisms, lactobacillus, and Escherichia coli. The "Radius of Zone of Inhibition (mm)- RZI" after 24 and 48 h were tested by the agar-well diffusion method. Results: For E. coli, the antibiotics tested were CV (5 µl and 2.5 µl), CF (5 µl and 2.5 µl), and Linezolid (5 µl and 2.5 µl). The results showed that the radius of the zone of inhibition was consistent for each antibiotic concentration, with a range of 0.8-1.4 mm at both time points. For Lactobacillus, the antibiotics tested were CV (5 µl and 2.5 µl), CF (5 µl and 2.5 µl), and Linezolid (5 µl and 2.5 µl). The results showed that the radius of the zone of inhibition varied between antibiotics and concentrations, with a range of 0.5-1.8 mm at both time points. Conclusion: This study highlights antibiotics' antibacterial action against E. coli and Lactobacillus. The data imply that antibiotic efficacy varied by organism and drug concentration. These organisms' antibiotic resistance mechanisms and new antibiotic resistance methods need more study.

Assessment of Polyetheretherketone Crown in Patients: An Original Research.

Introduction: Polyetheretherketone (PEEK) has a long history of usage in implant abutments, but it has not seen much applications in tooth-supported prosthetics. The purpose of this research was to examine the clinical performance of PEEK crowns as well as the level of patient satisfaction with them. The pilot study was designed as an in vivo longitudinal examination. Material and Methods: Twenty patients each received a PEEK crown during the procedure. In total, 22 implants were inserted, with 11 going into the maxilla and 9 into the mandible. One operator was responsible for carrying out each phase of the procedure. The resin cement was used to lute the crowns that were produced. Baseline, 3 months, 6 months, and 1 year after the crowns were placed, they were evaluated for various parameters using Modified Ryge's Criteria. These evaluations were performed at intervals of 3 months, 6 months, and 1 year. In addition, a questionnaire was used at the same time to assess the level of satisfaction felt by patients. Fisher's exact test was utilized in the process of analyzing the data that were gathered. Results: According to the findings, 92.5% of the crowns met the modified version of Ryge's criterion for a satisfactory rating. Three crowns had a fracture recorded. There was some chipping off observed in five of the crowns. There was not any significant difference in the other factors that were examined. The periodontal health of these three patients showed a slight degree of variance (P = 0.02). Conclusion: The capacity of PEEK crowns to create high-quality prostheses that were deemed satisfactory with a reasonably low rate of fracture during the relative mean duration of 1 year was established by the application of Modified Ryge's Criteria. The PEEK crowns demonstrated their ability to produce quality prostheses.

Association of the Antidepressants and the Periodontal Status: An Original Research.

Antidepressants have anti-inflammatory effects and boost immunity, and dentists should be aware. This case-control study included only those patients who consented to take part and had a ham-d score of at least 16 and a diagnosis of moderate-to-severe depression. Inclusion criteria included adults, those experiencing moderate to severe depression, taking fluoxetine or venlafaxine, and those with twenty or more teeth. Exclusion criteria included tobacco chewers, smokers, women expecting or nursing, periodontal treatment, antibiotics, anti-inflammatory medication, or vitamin/nutritional supplements. Patients who had had surgery or other therapy were excluded from the study. Three groups of patients were created: Control, venlafaxine, and fluoxetine. A periodontist assisted in the dental examination, and indices were observed. The analysis was done using Statistical Package for the Social Sciences (SPSS) version 24.0. Number, percentage, mean, and standard deviation were used to present the values. Results showed that antidepressants may be a risk factor for periodontal health, with increased periodontal parameters, and concluded that It is crucial to frequently check the periodontal health of depressed people using fluoxetine or venlafaxine since these drugs put good periodontal tissues at risk.