[The influence of drug supported initial treatment on the content of interleukin 1 in the gingival sulcus fluid in patients with plaque associated gingivitis]. / Der Einfluss der medikamentös unterstützten Initialtherapie auf den Interleukin-1-(IL 1) Gehalt in der Sulkusflüssigkeit von Patienten mit plaqueassoziierter Gingivitis.

In 32 patients with plaque associated gingivitis the effect of initial treatment for 2 respectively 4 weeks on the gingival index (GI) and the interleukin 1 (IL 1) content in the gingival sulcus fluid (SSF) was investigated. After successful clinical treatment a decrease of the IL 1 level was found. The importance of the IL 1 content of the gingival sulcus fluid as a sensitive parameter for therapy control is discussed.

[Interleukin 1 (IL 1) in gingival fluid from patients with plaque induced gingivitis]. / Der Interluekin-1 (IL 1)-Gehalt in der Sulkusflüssigkeit von Patienten mit plaqueassoziierter Gingivitis.

The level of interleukin 1 in gingival fluid is determined in 17 volunteers with healthy gingiva and in 58 patients with gingivitis of different severity. Continously increased levels of local IL 1 are found in connection with increased plaque accumulation in the dentogingival sites and with exacerbating gingival inflammation. The relevance of IL 1 in gingival fluid as a sensitive indicator of plaque-associated gingivitis is discussed.