RESUMO
AIM: The type of malocclusion most often seen in beta thalassemic patients is represented by Angle's II class, which however cannot be considered significant in the patients studied in this research. The only causal factor indicated by medical literature for this pathology is medullary hyperplasia due to inefficient erythropoiesis which occurs in patients transfused at low hemoglobin levels. The aim of this research is to evaluate the influence of other factors as well, particularly sexual development, the level of seric ferritin, ALT, and age at first transfusion. METHODS: One-hundred and twenty-two b thalassemic patients and 39 homozygotes, aged between 16 and 27, undergoing treatment at the "Ospedale Regionale per le Microcitemie di Cagliari", have been analysed. RESULTS: The results of the statistic analysis have shown that hypogonadism can play an important role in determining malocclusions in male beta thalassemic patients (Odds ratio 4,5; CI 1,5-13). No other factor has shown any statistically relevant influence on dental occlusion. CONCLUSION: It would therefore be interesting to further investigate the hormonal mechanisms that can alter bone development in thalassemic youngsters: the prevention of such alterations will surely contribute to improving the quality of life in these patients, particularly now that their life expectancy has been significantly extended by the progress made in transfusional therapy and ferrochelation.
Assuntos
Hipogonadismo/complicações , Má Oclusão Classe II de Angle/etiologia , Talassemia beta/complicações , Adolescente , Adulto , Transfusão de Sangue , Humanos , Hipogonadismo/fisiopatologia , Ferro/sangue , Masculino , Má Oclusão Classe II de Angle/fisiopatologia , Fatores de Risco , Talassemia beta/sangue , Talassemia beta/terapiaAssuntos
Assistência Ambulatorial , Anti-Inflamatórios/uso terapêutico , Ácidos Indolacéticos/uso terapêutico , Periodontite Periapical/tratamento farmacológico , Periodontite/tratamento farmacológico , Adolescente , Adulto , Criança , Avaliação de Medicamentos , Quimioterapia Combinada , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Penicilinas/uso terapêutico , Fatores de TempoRESUMO
The AA., after to have passed in review etiopathogenetic interpretations of odontomas and symptomatology, report 12 cases, from Odontostomatologic Clinic of Cagliari, dwelling on one of them especially, where the two epithelial and connective components, made evident microscopically, let foresee probable reductions either connective eithen epithelial component.
Assuntos
Neoplasias Maxilomandibulares/patologia , Tumores Odontogênicos/patologia , Odontoma/patologia , Adolescente , Adulto , Feminino , Humanos , MasculinoRESUMO
The AA. examine 14,987 bioptic investigations comings from Anatomy and Pathologic Histology Institute of Cagliari University relieved during the period 1936-1968 (twenty-eight years). They stop on main data giving prominence to: incidence of stomatologic cases, of benignant and malignant tumours, of inflammatory and precancerous states in the mouth. They moreover describe neoplasia frequency in reference to histologic type, to sex, to age and to localization.
Assuntos
Neoplasias Bucais/epidemiologia , Adulto , Idoso , Feminino , Humanos , Itália/epidemiologia , Masculino , Pessoa de Meia-Idade , Lesões Pré-Cancerosas/epidemiologiaRESUMO
The authors in epidemiologic research on dental caries of primary-school children in a village having optimufluorotic water, put in evidence fluorine paradox phenomena founding high percentual of cariopatic subjects.
Assuntos
Cárie Dentária/prevenção & controle , Fluoretação , Adolescente , Criança , Cárie Dentária/epidemiologia , Humanos , Itália/epidemiologiaRESUMO
The AA. describe a case of bone producing fibroma rising in a young patient after the drawing of a tooth. Histological reports, effected with different methods, confirmed this diagnosis.
Assuntos
Fibroma/patologia , Neoplasias Maxilares/patologia , Osteoma/patologia , Adulto , Feminino , HumanosRESUMO
The AA. report a case treated with cyst-enucleation, apicaectomy and tooth replantation and then prosthetic management, which they control for the last twenty years, and beyond initial expectations, they could establish an astonishing result indeed.