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J Fluoresc ; 30(6): 1411-1419, 2020 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-32930925

RESUMO

In this article, the characterization, synthesis, as well as the photocatalysis dye degradation performance of two novel silver(I) coordination polymers, namely, [Ag(L)(Hbdc)]n (1, L = 1,4-Bis(5,6-dimethylbenzimidazol-1-yl)butane, H2bdc = 1,4-Benzenedicarboxylic acid) and [Ag2(L)(hip)]n (2, H2hip = 5-Hydroxyisophthalic acid), were investigated. Fascinatingly, the photocatalytic performance of Complexes 1 and 2 have been investigated, wherein Complex 2 is considered an excellent photocatalyst for degrading Rhodamine B/methyl violet/methylene blue mixed organic dyes. Furthermore, the treatment activities of Complexes 1 and 2 on Tic disorder (TD) were assessed when used with haloperidol, and biochemical studies were conducted to reveal the mechanism in detail. Initially, the enzyme-linked immunosorbent assay was carried out to determine the dopamine and high vanillic acid contents in the striatum of the TD animal model. Subsequently, the reverse transcription-polymerase chain reaction was utilized to determine the relative expression of dopamine 1 and 2 receptor.


Assuntos
Complexos de Coordenação/química , Haloperidol/farmacologia , Neurotransmissores/metabolismo , Polímeros/química , Polímeros/farmacologia , Prata/química , Transtornos de Tique/tratamento farmacológico , Catálise , Criança , Sinergismo Farmacológico , Regulação da Expressão Gênica/efeitos dos fármacos , Haloperidol/uso terapêutico , Humanos , Processos Fotoquímicos , Receptores Dopaminérgicos/metabolismo , Transtornos de Tique/metabolismo
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