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J Am Acad Dermatol ; 62(5): 824-30, 2010 May.
Artigo em Inglês | MEDLINE | ID: mdl-20398812

RESUMO

BACKGROUND: Dermicol-P35 27G and 30G are purified advanced collagen dermal fillers that are effective and well tolerated for cosmetic procedures. OBJECTIVE: The primary objectives of this study were to: (1) document recovery time and return to daily activities after treatment with Dermicol-P35 27G, 30G, or both; and (2) assess the immediate adverse effects of these products and monitor their time to resolution. METHODS: In all, 30 patients were treated with Dermicol-P35 27G, 30G, or both in nasolabial folds, lips, corners of the mouth, vermillion border, marionette lines, or a combination of these and monitored for 7 days. Comfort with resuming daily routine, adverse events, and satisfaction with results were documented by patients in diaries. The clinician assessed aesthetic improvement and rated satisfaction with results. RESULTS: The majority of patients (63.4%) were very comfortable or comfortable returning to their daily routine immediately postprocedure. Most patients (86.7%) participated in normal work or social events within 2 days of treatment. Adverse events were mild to moderate and were resolved or tolerable by day 7. The clinician assessed that most patients had between 50% and 100% improvement over baseline for all procedures at all time points. Clinician and patients were very satisfied or satisfied with aesthetic results at days 2 and 7 postprocedure. LIMITATIONS: The limitations of this study were the small number of patients, the assessment of short-term results, and the lack of touch-up injections. CONCLUSIONS: Treatment with Dermicol-P35 27G, 30G, or both allowed for rapid return to daily activities and produced only transient and tolerable adverse events.


Assuntos
Colágeno/administração & dosagem , Técnicas Cosméticas , Adulto , Animais , Materiais Biocompatíveis/administração & dosagem , Materiais Biocompatíveis/efeitos adversos , Colágeno/efeitos adversos , Técnicas Cosméticas/efeitos adversos , Face , Feminino , Humanos , Injeções Subcutâneas , Lábio , Masculino , Pessoa de Meia-Idade , Satisfação do Paciente , Rejuvenescimento , Envelhecimento da Pele/efeitos dos fármacos , Suínos , Resultado do Tratamento
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