Group 4 ITI Consensus Report: Patient benefits following implant treatment in partially and fully edentulous patients.

OBJECTIVES: The aim of Working Group 4 was to address patient benefits associated with implant dentistry. Focused questions on (a) dental patient-reported outcomes (dPROs), (b) improvement in orofacial function, and (c) preservation of orofacial tissues in partially and fully edentulous patients following provision of implant-retained/supported dental prostheses were addressed. MATERIALS AND METHODS: Three systematic reviews formed the basis for discussion. Participants developed statements and recommendations determined by group consensus based on the findings of the systematic reviews. These were then presented and accepted following further discussion and modifications as required by the plenary of the 7th ITI Consensus Conference, taking place in 2023 in Lisbon, Portugal. RESULTS: Edentulous patients wearing complete dentures (CD) experience substantial improvements in overall dPROs and orofacial function following treatment with either complete implant-supported fixed dental prostheses (CIFDP) or implant overdentures (IODs). With respect to dPROs, mandibular IODs retained by two implants are superior to IODs retained by one implant. However, increasing the number of implants beyond two, does not further improve dPROs. In fully edentulous patients, rehabilitation with CIFDP or IOD is recommended to benefit the preservation of alveolar bone and masseter muscle thickness. CONCLUSIONS: Completely edentulous patients benefit substantially when at least the mandible is restored using an CIFDP or an IOD compared to CD. In fully edentulous patients, implant prostheses are the best option for tooth replacement. The availability of this treatment modality should be actively promoted in all edentulous communities, including those with limited access and means.

A comparative retrospective study of different surgical guide designs for static computer-assisted implant surgery in posterior single edentulous sites.

AIM: The aim of this retrospective clinical study was to compare the accuracy of static Computer-assisted implant surgery (sCAIS) in posterior single edentulous patients using different surgical guide designs. MATERIALS AND METHODS: Thirty-seven partially edentulous patients with a total of 54 implants were included in the study. Seventeen implants were included in Group 1-Unbounded Tooth-Mucosa Supported; 18 implants in Group 2-Unbounded Tooth Supported; and 19 implants in Group 3 (Control)-Bounded Tooth Supported. All partially edentulous patients were treated with fully guided implant surgery using the corresponding surgical guide. Discrepancies between the pre-planned and post-operative implant position were evaluated. RESULTS: The mean angular deviation ± standard deviation (SD) was 2.91 ± 1.56°, 3.33 ± 1.72° and 2.25 ± 1.13° for Groups 1, 2, and 3, respectively. The mean ± SD 3D offset at base was 0.66 ± 0.29 mm, 0.77 ± 0.24 mm, and 0.49 ± 0.22 mm; and 3D offset at tip was 0.84 ± 0.45 mm, 1.07 ± 0.38 mm, and 0.75 ± 0.25 mm for Groups 1, 2, and 3, respectively. No statistically significant differences between groups were found for angular deviation. There were statistically significant differences between Groups 2 and 3 for 3D offset at base (p = .002) and 3D offset at tip (p = .010). CONCLUSIONS: Different surgical guide designs for posterior single edentulous areas appear to be associated with the accuracy level of sCAIS. In unbounded sites, having additional posterior attached soft tissue support is preferable.

Comparative analysis of dimensional alterations following extraction of maxillary molars using three-dimensional images' superimposition: a CBCT study.

The aims of this study were to (i) evaluate the bone alterations following maxillary molar extraction and (ii) identify the factors associated with bone alterations using a tomographic analysis. Cone Beam Computer Tomographies (CBCTs) of 17 subjects with 25 maxillary molars were analyzed, before and, in average, 12 months following extraction. Fifty CBCTs were segmented as 3D models that were used as reference for analysis. Cross-sectional planes were established to measure the dimensional changes in the vertical, horizontal aspects, and the area of the alveolar bone. Associations between root divergence, initial bone location related to the maxillary sinus, and the thickness of buccal and palatal bone at baseline was assessed using mixed-effect models. Overall, the average reduction in vertical bone height was 35.23% (2.61 ± 1.76 mm). The mean reduction of area of alveolar process and horizontal bone width were 18.89% (56.08 ± 44.23 mm2) and 65.10% (8.33 ± 4.51 mm), respectively. There was a marginal significant association between horizontal bone changes and the thickness of palatal bone (p = 0.05). The results of the present study indicated that following maxillary molar extraction, significant dimensional changes occur in both the vertical and horizontal directions. The vertical changes were mainly attributed to remodeling on the coronal aspect of the alveolar ridge and sinus pneumatization was rare.

Influence of zirconia crown artifacts on cone beam computed tomography scans and image superimposition of tomographic image and tooth surface scan: An in vitro study.

STATEMENT OF PROBLEM: Zirconia restorations create significant artifacts on 3D cone beam computed tomography (CBCT) imaging. Static computer-assisted implant surgery (s-CAIS) relies on the accuracy of superimposition between an intraoral surface scan and CBCT imaging. However, how the artifacts from zirconia on the tomographic image might affect the predictability of s-CAIS is unclear. PURPOSE: The purpose of this in vitro study was to evaluate the effect of zirconia crown restorations on the superimposition process for s-CAIS. MATERIAL AND METHODS: Four stone casts generated 4 groups: a control group (CG) with no crowns and 3 experimental groups with 4 (TG4), 7 (TG7), and 13 (TG13) zirconia crowns. A total of 40 CBCT scans were made for the 4 groups (n=10). All CBCTs were imported into a computer planning software program, and the casts from all 4 groups were scanned by using a high-resolution laboratory scanner. The standard tessellation language (STL) files were imported, segmented, and the 3 files superimposed for all groups. The accuracy of the superimposition was assessed, in millimeters, in 3 planes corresponding to anterior-posterior, horizontal, and vertical, as well as the overall measurement, and the results were analyzed statistically (α=.05). RESULTS: The overall analysis demonstrated statistically significant differences between all groups (P<.001), except between CG and TG4. The anterior-posterior dimension demonstrated significant differences between CG and TG7 (P<.001), CG and TG13 (P<.001), TG4 and TG7 (P=.004), and TG4 and TG13 (P=.001). For the vertical dimension analysis, significant differences were found between CG and TG7 (P=.001), CG and TG13 (P<.001), and TG4 and TG13 (P<.001). For the horizontal variable, statistically significant differences were found between CG and TG7 (P=.049), CG and TG13 (P<.001), TG4 and TG13 (P<.001), and TG7 and TG13 (P=.003). CONCLUSIONS: The accuracy of the superimposition of the images was influenced by the number of zirconia crowns, with an increased number reducing the superimposition accuracy.

Effect of time in function on the predictability of short dental implants (≤6 mm): A meta-analysis.

PURPOSE: To analyse randomised controlled clinical trials (RCTs) and prospective cohort studies reporting on the survival and failure rates of functionally loaded short implants (SI) based on the actual length of time in function. MATERIALS AND METHODS: This meta-analysis was conducted according to PRISMA guidelines for systematic reviews. Electronic and manual searches were conducted to identify RCTs and prospective cohort studies reporting survival and complication rates of short dental implants (≤6 mm) based on the time in function. Secondary outcomes included the location (maxilla or mandible), type of restoration (single crown [SC] versus fixed dental prosthesis [FDP]) and marginal bone loss (MBL). RESULTS: A total of 20 studies (11 RCTs and 9 prospective) fulfilled the inclusion criteria and featured a total of 1238 SI placed in 747 patients. The overall (early and late) mean percentage of short implant failure was 4%. SI with up to 1-year follow-up presented failure rate of 2%, while SI followed up for >3 years showed a failure rate of 10%. SI restored with SC presented a late failure rate of 4% while SI restored with FPD 2%. The late failure rate did not differ in terms of location (maxilla or mandible) both with 3%. CONCLUSION: Short implants in function for more than 3 years presented higher failure rates compared to SI in function for <3 years. Splinting crowns supported by SIs in the posterior area should be considered. However, SI is a valid option for selected cases given their relatively high long-term survival rates.

Histological and micro-CT analysis of peri-implant soft and hard tissue healing on implants with different healing abutments configurations.

OBJECTIVE: The aim of this study was to assess the effect of different abutment configurations on peri-implant soft and hard tissue healing. MATERIALS AND METHODS: Two-piece dental implants, 3.5 mm in diameter and 8 mm in length, were placed in four beagle dogs. Two different transmucosal healing abutment configurations were randomly selected: one with a wide emergence profile (WE) (45° angulation with implant long axis) and the other with a narrow emergence profile (NE) (15° angulation with implant long axis). After four months of healing, the animals were sacrificed. Micro-CT scans were taken for mesio-distal analysis; subsequently, the biopsies were prepared for bucco-lingual histometric analyses. Several measurements were taken using the following reference points: marginal mucosal level (MML), apical barrier epithelium (aBE), implant shoulder (IS), marginal bone crest (BC), and first bone-to-implant contact (fBIC). RESULTS: In the micro-CT analysis, the distance from IS-fBIC was 1.11 ± 0.66 mm for WE and 0.12 ± 0.21 mm for NE (p = 0.004). The IS-BC of WE was -0.54 ± 0.80 mm, whereas NE presented 0.76 ± 0.48 mm (p = 0.002). The histometric analysis showed that both groups presented comparable dimensions of peri-implant biologic width (p > 0.05). However, in the distance from IS to BC, the WE showed a mean distance of -0.66 ± 0.78 mm while NE was 0.06 ± 0.42 mm (p = 0.039); the IS to fBIC was 0.89 ± 0.68 mm for WE while NE was 0.30 ± 0.30 mm (p = 0.041). CONCLUSION: The design of the transmucosal component can influence the establishment of the peri-implant biologic width. The flat and wide emergence profile induced an apical displacement of the peri-implant biologic width and more bone loss.

Narrow- and regular-diameter implants in the posterior region of the jaws to support single crowns: A 3-year split-mouth randomized clinical trial.

OBJECTIVES: The objective of this 3-year split-mouth randomized controlled clinical study was to compare narrow-diameter implants (NDIs) to regular-diameter implants (RDIs) in the posterior region of the jaws (premolars and molars) in regards to (i) the marginal bone level (MBL) and (ii) implant and prosthesis survival and success rates. MATERIAL AND METHODS: A total of 22 patients were included in the study. Each patient received at least one implant of each diameter (Ø3.3 and Ø4.1 mm), placed either in the maxilla or mandible to support single crowns. A total 44 implants (22 NDIs and 22 RDIs) were placed and included in the study. Twenty-one implants were placed in the premolar, whereas 23 were placed in molar areas. Radiographic evaluations to access the MBL were performed immediately after implant placement, 1 and 3 years after implant loading. Peri-implant clinical variables including probing pocket depth (PPD) and bleeding on probing (BoP) were obtained after crown delivery, 1 and 3 years after loading. Furthermore, the survival and success rates of the implants and prosthesis were also evaluated. RESULTS: Twenty patients were able to complete the study. There was no statistically significant difference regarding MBL between groups at implant placement (p = .084), 1-year (p = .794) and 3-year (p = .598) time intervals. The mean peri-implant bone loss at 3-year follow-up was -0.58 ± 0.39 mm (95% CI: -0.751 to -0.409) and -0.53 ± 0.46 mm (95% CI: -0.731 to -0.329) for NDIs and RDIs, respectively. BoP was present at 15% and 10% of NDIs and RDIs, respectively, at 3-year follow-up. PPD >5 mm was observed in 5% and 0% of the implants of NDIs and RDIs, respectively, at 3-year follow-up. At the 3-year examination, the implant success rates were in the NDIs and RDIs sites, respectively, 95% and 100%. The corresponding values for prosthesis success rates were 90% for NDIs and 95% for RDIs. CONCLUSION: The present study demonstrated that NDIs placed to support single crowns in the posterior region did not differ to RDIs in regards to MBL, implant survival, and success rates.

Short-term changes on C-reactive protein (CRP) levels after non-surgical periodontal treatment in systemically healthy individuals.

OBJECTIVES: The aim of the present study was to evaluate serum C-reactive protein (CRP) levels in chronic periodontitis patients and periodontally healthy individuals and to assess the effect of non-surgical periodontal treatment on the CRP levels. MATERIALS AND METHODS: Twenty-two patients with chronic periodontitis (test group) and 22 periodontally healthy individuals (control group), both groups without any systemic disorder or potential confounding factors, were included in the study. At baseline, periodontal clinical variables and CRP levels were obtained in both groups. In the test group, oral hygiene instruction and scaling and root planning were carried out; then, after 60 days, periodontal clinical variables and CRP levels were reevaluated. RESULTS: The baseline CRP level in the test group was significantly higher than the corresponding value in the control group (1.98 ± 1.55 vs. 1.26 ± 1.05 mg/L; p < 0.05). After periodontal treatment in the test group, there were improvements in all periodontal clinical variables (p < 0.05). The CRP level decreased significantly in those patients with higher baseline levels of CRP (>3 mg/L). CONCLUSIONS: Chronic periodontitis seemed to promote elevated levels of CRP. Furthermore, non-surgical periodontal treatment significantly decreased the levels of CRP only in patients with high baseline levels of such pro-inflammatory cytokine. CLINICAL RELEVANCE: Periodontitis may be a potential factor to change the risk of CVD. Thus, the control of periodontal infection performed by health professionals may improve cardiovascular health.

Restorative Alveolar Interface Management Combined With Tunnel Technique and Connective Tissue Graft: A Conservative Approach for Root Fracture Treatment.

INTRODUCTION: The infringement of supracrestal tissue attachment by subgingival restorative margins, extensive caries, and root fractures, can compromise the periodontal health, resulting in inflammation and loss of periodontal supporting tissues. This report describes a case of a root fracture on the upper left central incisor that was successfully treated using a conservative approach, by applying the restorative alveolar interface (RAI) management combined with tunnel technique and a subepithelial connective tissue graft (SCTG). CASE PRESENTATION: A 24-year-old male patient presented with a provisional single-unit fixed prosthesis on his upper left central incisor, in function for 4 years, with the chief complaint of prosthesis discoloration. After clinical and radiographic examination, a diagnosis of root fracture was established. Following the removal of the provisional prosthesis, a full-thickness flap was elevated creating a tunnel. The elimination of the fracture line/angle, root recontouring, and planning was then performed with the aid of a conical long diamond bur and periodontal curets. Additionally, an SCTG was placed buccally into the tunnel. The final zirconia layered with E-max crown was placed 6 months after surgery. At 12- and 24-month follow-up, the periodontal tissues presented healthy aspect, no bleeding on probing, and a 4-mm probing depth. CONCLUSIONS: Surgical repositioning of the restorative margin can be an alternative and conservative treatment approach to compromised teeth with subgingival fracture line/angle. However, case selection should be carefully considered and restorability assessed as limitations might apply.

Radiographic prevalence of unerupted and supernumerary teeth / Prevalência radiográfica de dentes não irrompidos e supranumerários

Objective: The objective of this study was to evaluate the prevalence of unerupted third molars and supernumerary teeth in patients from Maringá and region. Methods: Panoramic radiographs of patients treated in the Dental Clinic at Ingá School of Dentistry during 2009, were evaluated. The third molars were classified according to Pell and Gregory1 and Winter2 and the supernumerary teeth according to Garvey et al.3. The results were submitted to chi-square statistical testing (p<0.05). Results: Of a total of 411 panoramic x-rays evaluated, 113 subjects had unerupted third molars and 5 patients had supernumerary teeth. For the maxillary third molars the highest prevalence was in the A vertical position (p<0.05), and for mandibular third molars it was the mesio-angular position, class 1A (p<0.05). As for the supernumerary teeth, three were canines and two incisors, 2 being in the normal position, 2 inclined and 1 inverted.Conclusion: Based on the outcomes of the present study, it can be concluded that there is a high prevalence of unerupted third molars and a low prevalence of supernumerary teeth in the studied population.

Objetivo: Avaliar a prevalência dos terceiros molares não irrompidos e dentes supranumerários em indivíduos de Maringá e região. Métodos: Foram avaliadas as radiografias panorâmicas de pacientes atendidos na clínica odontológica da Faculdade Ingá durante o ano de 2009. A posição dos terceiros molares foi classificada de acordo com Pell & Gregory1 e Winter2 e os dentes supranumerários de acordo com Garvey3. Foram calculadas as frequências absolutas e relativas das variáveis estudadas e aplicado o teste Qui-quadrado (p<0.05). Resultados: De um total de 411 panorâmicas avaliadas, 113 indivíduos apresentavam terceiros molares não irrompidos e 5 pacientes tinham dentes supranumerários. Para os terceiros molares da maxila a maior prevalência foi da posição vertical A (p<0.05), e para a mandíbula foi posição mesioangular, classe 1A (p<0.05). Quanto aos dentes supranumerários, 3 eram caninos e 2 incisivos, sendo 2 na posição normal, 2 inclinados e 1 invertido.Conclusão: De um total de 411 panorâmicas avaliadas, 113 indivíduos apresentavam terceiros molares não irrompidos e 5 pacientes tinham dentes supranumerários. Para os terceiros molares da maxila a maior prevalência foi da posição vertical A (p<0.05), e para a mandíbula foi posição mesioangular, classe 1A (p<0.05). Quanto aos dentes supranumerários, 3 eram caninos e 2 incisivos, sendo 2 na posição normal, 2 inclinados e 1 invertido.

Avaliação do efeito do tratamento periodontal não-cirúrgico na hipersensibilidade dentinária / Evaluation of the non-surgical periodontal treatment effect on dentin hypersensitivity

Objetivo: avaliar o efeito do tratamento periodontal sobre a hipersensibilidade dentinária. Métodos: participaram do estudo 20 pacientes diagnosticados e tratados de periodontite crônica na Clínica Odontológica da Faculdade Ingá (Uningá), Maringá/PR. Os pacientes foram avaliados quanto à sensibilidade dentinária pela escala VAS antes do tratamento periodontal não-cirúrgico e 10 a 14 dias após seu término. Resultados: os pacientes apresentavam, antes do início do tratamento periodontal, uma sensibilidade média de 3,05±3,00, de acordo com a escala VAS. Ao final do tratamento houve uma diminuição significativa da hipersensibilidade dentinária, para um valor médio de 1,00±1,45. Conclusão: com base nos resultados obtidos, pôde-se concluir que o tratamento periodontal não-cirúrgico, associado a uma modificação dos hábitos de higiene, foi capaz de diminuir a hipersensibilidade dentinária em indivíduos com periodontite crônica.

Objectives: The aim of this study was to evaluate the periodontal treatment effect on dentin hypersensitivity. Methods: This study comprised 20 patients diagnosed and treated of chronic periodontitis in the Dental Clinic of Ingá School of Dentistry - Uningá (Maringá, Brazil). Patients were evaluated for dentin sensitivity by VAS scale before non-surgical periodontal treatment and after 10 to 14 days of its conclusion. Results: According to the VAS scale, patients presented an average sensitivity of 3.05 ± 3.00 before the beginning of periodontal treatment. At the end of the treatment there was a significant reduction to 1.00 ± 1.45 in the average dentin hypersensitivity. Conclusion: Based on the outcomes of the present study, it can be concluded that non-surgical periodontal treatment, associated to a modification of oral hygiene habits, was able to reduce dentin hypersensitivity in subjects with chronic periodontitis.

Avaliação da presença de fungos na cavidade bucal, e bolsas periodontais de indivíduos saudáveis e com doença periodontal / Evaluation of fungus presence in oral cavity and periodontal pockets of healthy individual and periodontal disease subjects

A microbiota da periodontite é complexa, aproximadamente 500 espécies bacterianas já foram encontradas nas bolsas periodontais. Alguns trabalhos mostram que fungos podem também estar associados à doença periodontal. Desta forma, o presente trabalho teve como objetivo avaliar a presença de fungos em pacientes com periodontite crônica, quais são os tipos de fungos presentes, e se os mesmos são encontrados também em pacientes periodontalmente saudáveis. Foram coletadas, por meio de cones de papel absorvente, amostras de biofilme das bolsas periodontais de 20 pacientes com doença periodontal crônica e dos sulcos gengivais de 20 pacientes periodontalmente saudáveis. Todos os pacientes também fizeram enxágue bucal para verificação de fungos na cavidade bucal. As amostras foram armazenadas em solução salina e semeadas em CHROMagar para determinar o crescimento de fungos, que depois foram identificados individualmente. Sete pacientes do grupo teste e nenhum do grupo controle apresentaram algum tipo de fungo na cavidade bucal e bolsas periodontais (p<0,05). A espécie mais comum foi de Candida tropicalis, seguida pela Candida albicans. Não houve diferença significativa quanto ao gênero ou faixa etária para a presença de fungos. Dentro dos limites do presente estudo pode se esperar encontrar fungos em cerca de 1 em cada 3 indivíduos com doença periodontal, independente do gênero ou idade.

The microbiota of periodontitis is complex and about 500 bacterial species have been found in periodontal pockets. Some studies show that fungi can also be associated with periodontal disease. Therefore, this study aimed to assess the presence of fungi in patients with chronic periodontitis, which types of fungi were present and if they are also found in periodontally healthy patients. Samples of biofilm from periodontal pockets of 20 patients with chronic periodontal disease and gingival crevices of 20 periodontally healthy patients were collected by means of absorbent paper cones All patients also had oral rinse for verification of fungi in the oral cavity. The samples were stored in saline solution and plated on CHROMagar to determine the growth of fungi. which have been individually identified. Seven patients in the test group and none in the control group had some type of fungus in the oral cavity and periodontal pockets (p < 0,05). The most common species was Candida tropicalis, followed by Candida albicans. There was no significant differences regarding gender or age for the presence of fungi. Withinthe limits of the present study. it can expect to find fungi in about 1 of 3 patients with periodontal disease, independent of gender or age.

A obesidade como fator de risco para doença periodontal: revisão de literatura / Obesity as a risk factor for periodontal disease: a literature review

A doença periodontal se caracteriza por um processo inflamatório no tecido periodontal de suporte, o qual tem como fator etiológico principal o biofilme dental, podendo ser essa uma inflamação gengival reversível (gengivite) ou irreversível, quando há uma perda de inserção conjuntiva e óssea (periodontite). A obesidade é considerada como fator de risco para diversas doenças sistêmicas, tais como hipertensão, diabetes melito tipo 2, doença coronariana e síndrome metabólica. Dessa forma, o objetivo deste estudo é apresentar as evidências científicas que relacionam a obesidade como um possível fator de risco para a doença periodontal. Onze estudos foram incluídos: nove estudos transversais e dois estudos de caso-controle. Todos os estudos analisados sugeriram uma relação entre a doença periodontal e a obesidade, no entanto os trabalhos apresentaram grande discrepância em relação à definição de doença periodontal e nos critérios utilizados na caracterização da obesidade. Apenas um estudo levou em consideração o sangramento à sondagem. Deste modo, baseado nas informações obtidas, não é possível afirmar que a obesidade tenha relação com as doenças periodontais.

Periodontal disease is characterized by the inflammation of periodontal tissues. The bacteria biofilm which is organized in subgingival is the main etiological factor. lt can range from a simple reversible gingival inflammation, called gingivitis, to attachment and bone loss, called periodontitis. Obesity is proven to be a risk factor for several systemic diseases such as hypertension, type 2 diabetes, coronary diseases and metabolic syndrome. The aim of the present review was to evaluate the available literature on the relationship between obesity and periodontal disease. Eleven studies were included in this review: 9 cross-sectional and 2 case-control studies. All the studies analyzed suggested a relationship between periodontal disease and obesity. There was, however, a large discrepancy concerning the definition of periodontal disease, as well as different criteria for measuring obesity and different populations, making the data non-comparable. Moreover, in just one study bleeding on probing was included among the periodontal measurements. Therefore, based on the information collected, it was not possible to demonstrate that obesity is actually related to periodontal diseases and, hence, that it can be considered as a risk factor.