RESUMO
Two new 7,8-secolignans, neglectahenols E and F (1 and 2), together with four known 7,8-secolignans (3-6), were isolated from the fruits of Schisandra neglecta. The structures were elucidated by spectroscopic methods, including extensive 1D and 2D NMR techniques. Compounds 1-6 were tested for their anti-tobacco mosaic virus (anti-TMV) activities at the concentration of 20 µM. Compounds 1 and 6 showed high anti-TMV activities with inhibition rates of 38.2% and 32.7%, respectively. These rates are higher than that of a positive control. Compounds 2-5 also showed modest anti-TMV activities with inhibition rates in the range of 22.8-28.7%. These rates are close to that of a positive control.
Assuntos
Antivirais/isolamento & purificação , Medicamentos de Ervas Chinesas/isolamento & purificação , Lignina/isolamento & purificação , Schisandra/química , Vírus do Mosaico do Tabaco/efeitos dos fármacos , Antivirais/química , Antivirais/farmacologia , Medicamentos de Ervas Chinesas/química , Medicamentos de Ervas Chinesas/farmacologia , Frutas/química , Lignanas , Lignina/química , Lignina/farmacologia , Estrutura Molecular , Ressonância Magnética Nuclear BiomolecularRESUMO
Optical microcavities are important for both fundamental studies of light-matter interaction and applications such as microlasers, optical switches and filters etc... Tunable microresonators, in which resonant modes can be manipulated, are especially fascinating. Here we demonstrate a unique approach to mechanically tuning microresonators formed by polymer droplets with varying sizes. The droplets are self-assembly inside an elastic medium. By incorporating different dye molecules into the droplets, optically pumped lasing with selective wavelengths in a range of about 100â nm are achieved. Lasing action is ascribed to whispering gallery modes, verified by rigorous characterizations. Single longitudinal mode lasing is obtained when the droplet diameter is reduced to about 14â µm. Tuning lasing modes are clearly demonstrated by mechanical deformation. Our finding provides an excellent platform for exploring flexible and tunable microlasers for plastic optoelectronic devices.