Detalhe da pesquisa
1.
Cationic Nanoliposomes Are Efficiently Taken up by Alveolar Macrophages but Have Little Access to Dendritic Cells and Interstitial Macrophages in the Normal and CpG-Stimulated Lungs.
Mol Pharm
; 16(5): 2048-2059, 2019 05 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-30965005
2.
Lipoid Pneumonia Associated with Polyethylene Glycol Chronic Aspiration.
Am J Respir Crit Care Med
; 207(8): e71-e72, 2023 04 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-36315868
3.
Impact of PEGylation on the mucolytic activity of recombinant human deoxyribonuclease I in cystic fibrosis sputum.
Clin Sci (Lond)
; 132(13): 1439-1452, 2018 07 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-29871879
4.
Synthesis and In Vitro Evaluation of Polyethylene Glycol-Paclitaxel Conjugates for Lung Cancer Therapy.
Pharm Res
; 33(7): 1671-81, 2016 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-26984129
5.
Nebulization of PEGylated recombinant human deoxyribonuclease I using vibrating membrane nebulizers: A technical feasibility study.
Eur J Pharm Sci
; 189: 106522, 2023 Oct 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37423579
6.
Impact of the PEG length and PEGylation site on the structural, thermodynamic, thermal, and proteolytic stability of mono-PEGylated alpha-1 antitrypsin.
Protein Sci
; 31(9): e4392, 2022 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-36040264
7.
Biodistribution and elimination pathways of PEGylated recombinant human deoxyribonuclease I after pulmonary delivery in mice.
J Control Release
; 329: 1054-1065, 2021 01 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-33091532
8.
Encapsulation of a CpG oligonucleotide in cationic liposomes enhances its local antitumor activity following pulmonary delivery in a murine model of metastatic lung cancer.
Int J Pharm
; 600: 120504, 2021 May 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33753161
9.
PEGylation of recombinant human deoxyribonuclease I decreases its transport across lung epithelial cells and uptake by macrophages.
Int J Pharm
; 593: 120107, 2021 Jan 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-33259904
10.
PEGylation of anti-sialoadhesin monoclonal antibodies enhances their inhibitory potencies without impairing endocytosis in mouse peritoneal macrophages.
Bioconjug Chem
; 20(2): 295-303, 2009 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-19143515
11.
The inhibitory potencies of monoclonal antibodies to the macrophage adhesion molecule sialoadhesin are greatly increased following PEGylation.
Bioconjug Chem
; 19(10): 2088-94, 2008 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-18808170
12.
Fate of PEGylated antibody fragments following delivery to the lungs: Influence of delivery site, PEG size and lung inflammation.
J Control Release
; 272: 62-71, 2018 02 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-29247664
13.
PEGylation prolongs the pulmonary retention of an anti-IL-17A Fab' antibody fragment after pulmonary delivery in three different species.
Int J Pharm
; 521(1-2): 120-129, 2017 Apr 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-28192159
14.
PEGylation of paclitaxel largely improves its safety and anti-tumor efficacy following pulmonary delivery in a mouse model of lung carcinoma.
J Control Release
; 239: 62-71, 2016 10 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-27515664
15.
PEGylation of antibody fragments greatly increases their local residence time following delivery to the respiratory tract.
J Control Release
; 187: 91-100, 2014 Aug 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-24845126
16.
Production, purification and biological characterization of mono-PEGylated anti-IL-17A antibody fragments.
Int J Pharm
; 454(1): 107-15, 2013 Sep 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-23850622
17.
Targeting the deep lungs, Poloxamer 407 and a CpG oligonucleotide optimize immune responses to Mycobacterium tuberculosis antigen 85A following pulmonary delivery.
Eur J Pharm Biopharm
; 84(1): 40-8, 2013 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-23238272
18.
Alveolar macrophages are a primary barrier to pulmonary absorption of macromolecules.
Am J Physiol Lung Cell Mol Physiol
; 286(5): L1002-8, 2004 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-14695119