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1.
Environ Res ; 197: 111057, 2021 06.
Artigo em Inglês | MEDLINE | ID: mdl-33757825

RESUMO

Considering the omnipresence of microplastics (MPs) in aquatic environments, they are expected to exert significatn impacts as carriers for diverse waterborne pollutants. In this work, the adsorptive behavior of two ionic components (i.e., sodium dodecyl benzene sulfonate (SDBS) and Cr(VI)) has been explored against the two types of MPs as model adsorbents, namely poly (ethylene terephthalate) (PET) and polystyrene (PS). The influence of key variables (e.g., pH, particle size, and dose of the MPs) on their adsorption behavior is evaluated from various respects. The maximum adsorption capacity values of SDBS on PET and PS are estimated to be 4.80 and 4.65 mg⋅g-1, respectively, while those of Cr(VI) ions are significantly lower at 0.080 and 0.072 mg⋅g-1, respectively, The adsorptive equilibrium of SDBS is best described in relation to pH and MP size by a Freundlich isotherm. In contrast, the adsorption behavior of Cr(VI) is best accounted for by a Langmuir isotherm to indicate its adsorption across at least two active surface sites.


Assuntos
Microplásticos , Poluentes Químicos da Água , Adsorção , Benzenossulfonatos , Cromo , Concentração de Íons de Hidrogênio , Cinética , Plásticos , Poluentes Químicos da Água/análise
2.
Med Sci Monit ; 25: 4384-4389, 2019 Jun 12.
Artigo em Inglês | MEDLINE | ID: mdl-31188801

RESUMO

BACKGROUND The restoration of damaged periodontium, especially one-wall intrabony defects, is a major challenge for clinicians. Concentrated growth factors (CGF) are a 100% autologous fibrin with multiple concentrated growth factors. The rigid fibrin structure of CGF makes it possible to preserve or reconstruct the initial bone volume. The aim of this study was to evaluate the clinical healing patterns after surgical application of CGF with and without a Bio-Oss graft in one-wall infrabony defects. MATERIAL AND METHODS We randomly divided 120 one-wall intrabony defects in 54 patients into 4 groups: flap surgery alone (Group 1), flap surgery with autologous CGF (Group 2), flap surgery with Bio-Oss (Group 3), and flap surgery with CGF+Bio-Oss (Group 4). Clinical parameters such as probing depth (PD) and clinical attachment level (CAL) change were recorded at baseline and at 6 and 12 months postoperatively. RESULTS At 12 months postoperatively, Group 2 showed significant improvement in clinical parameters over Group 1 (P<0.05) and the results were significantly greater in Groups 3 and 4 compared to the other groups (P<0.05). Although no significant difference was noted between Groups 3 and 4 in clinical parameters (P>0.05) compared to Group 3, the mean change of CAL at 6-12 months in Group 4 was not significant (P>0.05). CONCLUSIONS CGF reduced periodontal intrabony defects depth and, when mixed with Bio-Oss, CGF showed better results in the early period and the effect was more stable.


Assuntos
Substitutos Ósseos/farmacologia , Periodontite Crônica/tratamento farmacológico , Peptídeos e Proteínas de Sinalização Intercelular/farmacologia , Adulto , Perda do Osso Alveolar/tratamento farmacológico , Regeneração Óssea/efeitos dos fármacos , China , Feminino , Fibrina/farmacologia , Seguimentos , Humanos , Masculino , Doenças Mandibulares/tratamento farmacológico , Pessoa de Meia-Idade , Minerais/farmacologia , Índice Periodontal , Ligamento Periodontal , Cicatrização/efeitos dos fármacos
3.
Angew Chem Int Ed Engl ; 58(49): 17671-17674, 2019 12 02.
Artigo em Inglês | MEDLINE | ID: mdl-31545542

RESUMO

Upon incubation with Au nanocages, pyrrole (Py) molecules can enter the cavities by diffusing through the porous walls and then be polymerized to generate a polypyrrole (PPy) coating on the inner surface. The thicknesses of the PPy coating can serve as a direct indicator for the amount of Py molecules that diffuse into the cavity. Py molecules are able to diffuse into the cavities throughout the polymerization process, while a prolonged incubation time increases the amount of Py accumulated on both inner and outer surfaces of the nanocages. Furthermore, it is demonstrated that the dimensions of the cavity and the size of the pores in the wall are not critical parameters in determining the loading efficiency, as they do not affect the thickness of the PPy coating on the inner surface. These findings offer direct evidence to support the applications of Au nanocages as carriers for drug delivery and controlled release.


Assuntos
Ouro/química , Nanopartículas Metálicas/química , Polímeros/química , Pirróis/química , Adsorção , Tamanho da Partícula , Porosidade , Propriedades de Superfície
4.
Int J Biol Macromol ; 166: 578-586, 2021 Jan 01.
Artigo em Inglês | MEDLINE | ID: mdl-33137383

RESUMO

This research is focused on improving performance of chitosan based functional material by introducing active additive. A series of assays revealed incorporation with clove essential oil (CEO) significantly improved the physical, chemical and antimicrobial performance of chitosan. In this work, the prepared chitosan-CEO film (CH-CEO) showed varieties in color parameters, mechanical strength and water vapor permeability. Moreover, chitosan was endowed with significant antioxidant and antimicrobial activities, thereby it was used as protective coatings for fresh-cutting apple tubes at ~1 °C. Results demonstrated the treatment slowed down the quality deterioration process of preserved apple samples, especially for firmness and color. As well, CH-CEO coating reduced microbial counts in the preserved apple samples and inhibited the varieties in the chemical properties. The overall observations revealed that CH-CEO film has remarkable potential as an antioxidant and antimicrobial material, especially as an active coating for fresh-cutting foods during storage.


Assuntos
Quitosana/química , Óleo de Cravo/química , Materiais Revestidos Biocompatíveis/química , Antibacterianos/farmacologia , Antioxidantes/farmacologia , Óleo de Cravo/farmacologia , Cor , Malus , Testes de Sensibilidade Microbiana , Permeabilidade , Porosidade , Vapor
5.
World J Clin Cases ; 8(3): 624-629, 2020 Feb 06.
Artigo em Inglês | MEDLINE | ID: mdl-32110675

RESUMO

BACKGROUND: Oncologic immunotherapy is attracting attention as an effective strategy for cancer treatment. Currently, there are two kinds of inhibitors: Anti-PD-1 antibodies and anti-PD-L1 antibodies. These inhibitors have shown significant implications in improving the outcomes of certain cancer types in recent years. However, along with its effectiveness, adverse events cannot be ignored. As an anti-PD-1 antibody, camrelizumab (SHR-1210) has some side effects in tumor immunotherapy. The most common adverse event is reactive capillary hemangioma. While it is widely reported to occur in the skin, gingival reactive capillary hemangioma is rarely reported. CASE SUMMARY: A 54-year-old man complained of gingival overgrowth on the anterior aspect of the maxilla and mandible for more than 6 mo. He had been placed on SHR-1210 for lung cancer for 7 mo. A gingival mass extending from canine to canine was noted on the lingual surfaces of the mandible. Gingival enlargement was noted in the front teeth. A clinical diagnosis of gingival reactive capillary hemangioma and chronic periodontitis was made. The treatment involved a complex local treatment (repeated local applications of an antibiotic paste, scaling and root planning, and surgery). The excised tissue was sent for histopathological examination, which confirmed the diagnosis of capillary hemangioma. After the operation, most of the gingival enlargement was reduced. At the 2-mo follow-up, it was noted that the gingival overgrowth was immediately reduced after the replacement of the anti-PD-1 agent with an anti-PD-L1 agent. CONCLUSION: As the prescription for SHR-1210 has increased considerably in recent years, the occurrence of its possible side effects, including gingival reactive capillary hemangioma, has increased. It is recommended that regular oral examinations be performed before and during the treatment of tumors with SHR-1210.

6.
Environ Pollut ; 257: 113440, 2020 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-31706754

RESUMO

More attention was paid to the attachment between microplastics and environmental pollutants. The adsorption performance of Polyethylene (PE) beads (a typical type of microplastics) and Cr(VI) ions with the existence of sodium dodecyl benzene sulfonate (SDBS) was investigated in this paper. The adsorption experiments of Cr(VI) ions by PE microplastics were conducted at different conditions, i.e. PE doses, pH and SDBS concentrations, respectively. The adsorption capability of Cr(VI) ions was increased from 0.39 to 1.36 mg⋅g-1 when the dosage of PE microplastics was increased from 2 to 14 g ⋅L-1 at pH of 5 with addition of SDBS, compared with increasing adsorption capability from 0.03 to 0.32 mg⋅g-1 without addition of SDBS. The pH would influence the adsorption capability with and without the addition of SDBS. When the pH was less than 6, the adsorption capability of Cr(VI) would be promoted by the addition of SDBS; however, there was a contrast tendency when the pH was more than 6, which was attributed to that SDBS would compete with CrO42- for occupying the adsorption sites of PE microplastic. The SDBS concentration would affect the adsorption performance of Cr(VI) ions onto PE microplastics. The peak of the adsorption capacity was at SDBS concentration between 1 and 1.5 mM. This research would provide a basis for investigating the influence of SDBS on adsorption performance of heavy metal by PE microplastics to simulate the surface attachment model of those three kinds of pollutants.


Assuntos
Cromo/química , Microplásticos/química , Poluentes Químicos da Água/química , Adsorção , Benzenossulfonatos , Concentração de Íons de Hidrogênio , Íons , Metais Pesados , Modelos Químicos , Plásticos , Polietileno , Poluentes Químicos da Água/análise
7.
Hua Xi Kou Qiang Yi Xue Za Zhi ; 36(4): 461-463, 2018 Aug 01.
Artigo em Zh | MEDLINE | ID: mdl-30182578

RESUMO

Pregnancy epulis is a tumor-like lesion that results from aggravating gingivitis due to high level of gonadal hormone concentration. Pregnancy epulis is commonly manifested as a single lump. A case of multiple pregnancy epulises, which has been rarely explored, is reported in this paper. The patient received no other treatment but a single supragingival scaling. Results showed no remarkable changes in the lesion. However, all the epulides regressed spontaneously in five months after the parturition.


Assuntos
Placa Dentária , Gengivite , Complicações na Gravidez , Índice de Placa Dentária , Feminino , Gengivite/terapia , Humanos , Índice Periodontal , Gravidez , Complicações na Gravidez/terapia , Gravidez Múltipla
8.
Plant Physiol Biochem ; 62: 33-40, 2013 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-23178482

RESUMO

Alginate oligosaccharides (AOS) prepared from degradation of alginate is a potent plant elicitor. Hydroponic experiments were carried out to investigate the mechanism of AOS on improving Triticum aestivum L. resistant ability to drought stress. Drought model was simulated by exposing the roots of wheat to polyethylene glycol-6000 (PEG-6000) solution (150 g L(-1)) for 4 days and the growth of wheat treated with PEG was significantly decreased. However, after AOS application, seedling and root length, fresh weight and relative water content of wheat were increased by 18%, 26%, 43% and 33% under dehydration status compared with that of PEG group, respectively. Moreover, the antioxidative enzymes activities were obviously enhanced and malondialdehyde (MDA) content was reduced by 37.9% in samples treated by AOS. Additionally, the drought resistant related genes involved in ABA signal pathway, such as late embryogenesis abundant protein 1 gene (LEA1), psbA gene, Sucrose non-fermenting 1-related protein kinase 2 gene (SnRK2) and Pyrroline-5-Carboxylate Synthetase gene (P5CS) were up-regulated by AOS. Our results suggested that AOS might regulate ABA-dependent signal pathway to enhance drought stress resistance of wheat during growth period.


Assuntos
Alginatos/metabolismo , Oligossacarídeos/metabolismo , Raízes de Plantas/metabolismo , Estresse Fisiológico , Triticum/metabolismo , Antioxidantes/metabolismo , Ácido Glucurônico/genética , Ácido Glucurônico/metabolismo , Ácidos Hexurônicos/metabolismo , Malondialdeído/metabolismo , Oligossacarídeos/genética , Proteínas de Plantas/genética , Proteínas de Plantas/metabolismo , Raízes de Plantas/genética , Polietilenoglicóis/farmacologia , Tensoativos/farmacologia , Triticum/genética
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