New and innovative biomaterials, techniques and therapy concepts: Biologization in maxillofacial surgery, oral surgery and dentistry is in full swing. PRF, PRGF, PRP, blood plasma-stabilized augmentations, supplementation of micronutrients and vitamins - what opportunities do such "biological" approaches actually offer? We introduce them here.

Biomaterials of natural origin have recently gained increasing attention in the field of dental implantology. The requirements for such materials, however, are very high. In addition to high clinical efficiency in tissue regeneration, wound healing should be demonstrably positively influenced. The translational division for regenerative orofacial medicine of the Clinic and Polyclinic for Oral and Maxillofacial Surgery of the University Medical Center Hamburg-Eppendorf (UKE) is examining this research topic by investigating which innovative treatment methods for the reconstruction of bone defects or for augmentative procedures can be applied in the future or are already being applied in the field of oral and maxillofacial surgery.

Long-term recurrence rate of pleomorphic adenoma and postoperative facial nerve paresis (in parotid surgery).

BACKGROUND: The purpose of this study was to evaluate recurrence rates and comorbidity in patients with pleomorphic adenomas of patients after superficial and total conservative parotidectomy. PATIENTS AND METHODS: Localization of pleomorphic adenomas, age, sex distribution and facial nerve function of 73 patients were examined in this retrospective study. The recurrence rate could be determined in 43 of these patients. The interval between surgery and last recall varied between 2 and 20 years (median: 8.1 years). RESULTS: Most of the patients were female (67%) with a parotid pleomorphic adenoma. No recurrence was found regard less of whether a superficial or total conservative parotidectomy had been performed. Our data did show that the total conservative parotidectomy is associated with a higher incidence of temporary impaired facial nerve function, which was seen in 42% of this group. Temporary decreased nerve function after superficial parotidectomy was rare being apparent in only 16% of this group. CONCLUSION: A more radical procedure does not significantly lower the recurrence rate. We suggest that the indication for a total conservative parotidectomy in cases of superficial adenomas should be considered carefully.

Regenerative treatment of peri-implantitis bone defects with a combination of autologous bone and a demineralized xenogenic bone graft: a series of 36 defects.

AIM: As the treatment of peri-implantitis-induced bone loss is still a problem, we studied the regenerative treatment of these defects with a mix of autologous bone and a new type of bone graft substitute (demineralized xenogenic bone graft) including growth factors. MATERIAL AND METHODS: In a prospective manner, 36 cases of peri-implantitis-induced bone loss (depth >4 mm) in 22 patients were followed for 1 year. After resolving the acute infection by local rinsing, granulation tissue was removed. The implants were decontaminated with etching gel and the defects were filled with autologous bone mixed 1:1 with a xenogenic bone graft. The prosthetic reconstructions did not have to be removed. Values of probing depths as well as bone defects were analyzed. RESULTS: The radiologic evaluation of the bone defects after regenerative treatment revealed a mean reduction of 3.5 mm comparing the values from 5.1 mm prior to surgery to 1.6 mm 1 year after treatment. Average reduction of the probing depth was 4 mm. The remaining bone defects were larger than 3 mm in 4 out of 36 implants 1 year after treatment. Probing depths of more than 4 mm were present in seven implants. CONCLUSION: Within the limits of the study, we conclude that for bone defects larger than 4 mm in case of peri-implantitis, this single surgical intervention provided a reliable method to reduce bone defects.

[Facial aesthetics part I - the significance of the triangle of yarbus]. / Gesichtsästhetik Teil 1: Die Bedeutung der Symmetrieebene des Gesichts.

When humans observe a face, the eyes, mouth and nose regions are the preferred targets of the centre of gaze, with the outlines of eye position recordings approximating a triangle with vertices located in the centre of the eyes and mouth [31]. We studied the significance of cutaneous asymmetries inside and outside the Yarbus triangle on the basis of the assessment of digitally-manipulated images by 201 independent judges. We show that certain facial variations (such as naevi) are more attractive when asymmetrical than symmetrical (p<0,001). They appear more attractive when located laterally rather than medially, particularly so when located outside the Yarbus triangle as compared to inside it (p<0,001). The significance of facial symmetry increases significantly when approaching the Yarbus triangle or the midline, respectively.