Effects of silicone hydrogel contact lenses on ocular surface after Sub-Bowman's Keratomileusis.

PURPOSE: To evaluate the efficacy of silicone hydrogel contact lenses on ocular surface after Sub-Bowman Keratomileusis (SBK). MATERIALS AND METHODS: Forty-six patients suffered from myopia underwent a bilateral SBK. Post-operatively, one eye of each patient wore a PureVision contact lens for 24 h as a treated eye and the contralateral eye was as a blank control. Afterwards, corneal fluorescein (FL) staining, tear break-up time (TBUT), schirmer I test (SIT), central corneal thickness (CCT), ocular surface disease index (OSDI), corneal hysteresis (CH), corneal resistance factor (CRF) and corneal flap complications were assessed 1 d (except for CH and CRF), 1 week, 1 month and 3 months postoperatively. RESULTS: Following SBK, in contrast to the control, corneal fluorescein staining of treated eyes were significantly reduced and tear break-up time of treated eyes were significantly improved at 1 d and 1 week after SBK. However, Schirmer I test of treated and control eyes were not different after SBK. Central corneal thickness of treated eyes were significantly thinner than that of control at 1 d after SBK, however, there were no differences at other time points. Ocular surface disease index of treated eyes were obviously alleviated more than that of control at 1 d after SBK, but no differences were found at other visits. Moreover, Corneal hysteresis and corneal resistance factor of treated and un-treated eyes were not different after surgery. And also the rate of corneal flap complications were not different between treated and control eyes after SBK. CONCLUSIONS: Silicone hydrogel contact lenses played a positive role in accelerating corneal epithelial healing, enhancing tear film stability and reducing discomfort of patients in the early stage after SBK.

[The study of the therapeutic application of PV contact lens].

PURPOSE: To evaluate the indications and effects of continuously wearing the Bausch & Lomb Pure-Vision (PV)Contact Lens. METHOD: Twenty-nine patients (31 eyes) who required therapeutic contact lens wear were selected non-randomly from Zhongshan Ophthalmic Center for wearing (Pure Vision, PV) contact lens. Therapeutic indications included pain and irritation relief, corneal protection, and enhancement of corneal wound healing. Simultaneously antibiotics and artificial tears were used according to the ocular diseases. And then, the effect of treatment, anterior segment of eyes, contact lens fitting characteristics, lens deposits and the presence of contact lens-relative complications were evaluated. RESULTS: The duration of PV contact lens wear on 31 eyes were 3-57 days, averagely 20.9 days. Patients included bullous keratopathy (6 cases, 6 eyes), keratitis incorporated with descemetocele (5 cases, 5 eyes), chemical burns with epithelial abrasions (6 cases, 7 eyes), post-keratoplasty (3 cases, 3 eyes), filamentary keratitis (3 cases, 3 eyes), corneal epithelial erosion syndrome (2 cases, 3 eyes), repetitive corneal epithelial stripping syndrome (1 case, 1 eye), corneal lamellar laceration and epithelial coloboma (1 case, 1 eye), post-extraction of traumatic cataract with durative corneal ulcer (1 case, 1 eye), post-limbal & amnia transplantation (1 case, 1 eye). For the treatment of pain and irritation relief (21 patients, 22 eyes), all patients had complete or partial relief. For corneal healing (20 patients, 22 eyes), full healing was noted in 15 patients (16 eyes) (72.7%), partial healing occurred in 4 patients (5 eyes) (22.7%). For corneal protection (21 patients, 23 eyes), lens wear was fully protective in all cases, except one case of loosely fitting. Our result shows that PV Contact Lens exhibits prominent efficiency in CONCLUSION: treating corneal diseases and ocular surface diseases, as well as corneal protection, corneal healing and pain relief. The lens has increased oxygen transmissibility and good anti-deposit quality, reducing the risk of ocular complications. As a result of these, PV Contact Lens is the ideal bandage therapeutic lens.