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1.
BMC Oral Health ; 19(1): 254, 2019 11 21.
Artigo em Inglês | MEDLINE | ID: mdl-31752793

RESUMO

BACKGROUND: Although several studies assessed the prevalence of alveolar bone loss, the association with several risk factors has not been fully investigated. The aim of this article is to measure the prevalence of periodontitis by calculating the mean alveolar bone loss/level of posterior teeth using bitewing radiographs among the patients enrolled in the clinics at Harvard School of Dental Medicine and address risk factors associated with the disease. METHODS: One thousand one hundred thirty-one patients were selected for radiographic analysis to calculate the mean alveolar bone loss/level by measuring the distance between the cementoenamel junction and the alveolar bone crest on the mesial and distal surfaces of posterior teeth. Linear regression with Multi-level mixed-effect model was used for statistical analysis adjusting for age, sex, race, median household income, and other variables. RESULTS: Mean alveolar bone level of the whole sample was 1.30 mm (±0.006). Overall periodontitis prevalence for the sample was 55.5% (±1.4%). Moderate periodontitis prevalence was 20.7% (±1.2%), while 2.8% (±0.5%) of the whole sample had severe periodontitis. Adjusted mean alveolar bone loss was higher in older age groups, males, Asian race group, ever smokers, and patients with low median household income. CONCLUSION: The effect of high household income on the amount of bone loss can be powerful to the degree that high household income can influence outcomes even for individuals who had higher risks of developing the disease. Public health professionals and clinicians need to collaborate with policy makers to achieve and sustain high quality of healthcare for everyone.


Assuntos
Perda do Osso Alveolar , Periodontite , Idoso , Perda do Osso Alveolar/etiologia , Processo Alveolar , Boston/epidemiologia , Assistência Odontológica , Feminino , Humanos , Masculino , Periodontite/complicações , Periodontite/epidemiologia , Prevalência
2.
J Arthroplasty ; 33(10): 3231-3237, 2018 10.
Artigo em Inglês | MEDLINE | ID: mdl-29958755

RESUMO

BACKGROUND: Adverse local tissue reactions (ALTRs) due to tribocorrosion of head-neck taper junctions in contemporary metal-on-polyethylene (MoP) total hip arthroplasty (THA) are emerging as an important reason for failure requiring revision surgery. This study aimed at: (1) reporting early complication rates and outcome, and (2) identifying risk factors associated with complications of revision surgery for head-neck taper corrosion in patients with MoP THA. METHODS: Forty consecutive revision surgeries in 39 patients (male, 16; female, 23) with MoP THA were evaluated. The follow-up period after revision was a minimum of 14 months (range, 14-45). The indication for revision surgery was the presence of symptomatic ALTR on magnetic resonance imaging (MRI) with elevated metal ion levels. RESULTS: The overall complication rate was 25% and the reoperation rate was 10%. The median serum level of cobalt ions decreased significantly 8.2 µg/L (1.2-56.1 µg/L) pre-revision to 3.1 µg/L (0.2-14.0 µg/L) post-revision (P < .01). High fretting and corrosion grades (Goldberg score ≥ 3) were observed in 82% of retrieved implants. MRI findings of solid lesion(s) with abductor deficiency (P < .01) and intraoperative tissue damage at revision (P = .02) were significantly associated with post-revision complications. CONCLUSION: A high rate of early complications (25%) and re-revisions (10%) was observed after revision of ALTR associated with head-neck taper corrosion. Pre-revision MRI findings of solid lesion(s) with abductor deficiency and intraoperative tissue damage were risk factors associated with the occurrence of a complication after revision surgery. This information provides clinically useful information for clinical decision-making and preoperative counseling of MoP THA patients undergoing revision surgery for head-neck taper corrosion.


Assuntos
Artroplastia de Quadril/efeitos adversos , Prótese de Quadril/efeitos adversos , Complicações Pós-Operatórias/epidemiologia , Reoperação/efeitos adversos , Idoso , Idoso de 80 Anos ou mais , Artroplastia de Quadril/estatística & dados numéricos , Boston/epidemiologia , Cromo/sangue , Cobalto/sangue , Corrosão , Feminino , Prótese de Quadril/estatística & dados numéricos , Humanos , Íons , Imageamento por Ressonância Magnética , Masculino , Metais/sangue , Pessoa de Meia-Idade , Polietileno , Complicações Pós-Operatórias/etiologia , Desenho de Prótese , Falha de Prótese , Reoperação/estatística & dados numéricos , Fatores de Risco
3.
Nicotine Tob Res ; 18(5): 1282-1289, 2016 May.
Artigo em Inglês | MEDLINE | ID: mdl-26508397

RESUMO

INTRODUCTION: In 2012, the Boston Housing Authority (BHA) in Massachusetts implemented a smoke-free policy prohibiting smoking within its residences. We sought to characterize BHA resident experiences before and after the smoke-free policy implementation, and compare them to that of nearby residents of the Cambridge Housing Authority, which had no such policy. METHODS: We recruited a convenience sample of nonsmoking residents from the BHA and Cambridge Housing Authority. We measured residents' awareness and support of their local smoking policies before and 9-12 months after the BHA's policy implementation, as well as BHA respondents' attitudes towards the smoke-free policy. We assessed tobacco smoke exposure via saliva cotinine, airborne apartment nicotine, and self-reported number of days smelling smoke in the home. We evaluated predictors of general satisfaction at follow-up using linear regression. RESULTS: At follow-up, 91% of BHA respondents knew that smoking was not allowed in apartments and 82% were supportive of such a policy in their building. BHA residents believed enforcement of the smoke-free policy was low. Fifty-one percent of BHA respondents indicated that other residents "never" or "rarely" followed the new smoke-free rule and 41% of respondents were dissatisfied with policy enforcement. Dissatisfaction with enforcement was the strongest predictor of general housing satisfaction, while objective and self-reported measures of tobacco smoke exposure were not predictive of satisfaction. At follow-up, 24% of BHA participants had complained to someone in charge about policy violations. CONCLUSIONS: Resident support for smoke-free policies is high. However, lack of enforcement of smoke-free policies may cause frustration and resentment among residents, potentially leading to a decrease in housing satisfaction. IMPLICATIONS: Smoke-free housing laws are becoming increasingly prevalent, yet little is known about satisfaction and compliance with such policies post-implementation. We evaluated nonsmoking residents' attitudes about smoke-free rules and their satisfaction with enforcement 1 year after the BHA implemented its comprehensive smoke-free policy. We found that while residents were supportive of the policy, they believed enforcement was low, a perception that was associated with a drop in housing satisfaction. Our findings point to a desire for smoke-free housing among public housing residents, and the importance of establishing systems and guidelines to help landlords monitor and enforce these policies effectively.


Assuntos
Atitude Frente a Saúde , Habitação/legislação & jurisprudência , Satisfação Pessoal , Política Antifumo/legislação & jurisprudência , Fumar/legislação & jurisprudência , Poluição por Fumaça de Tabaco/legislação & jurisprudência , Adulto , Boston/epidemiologia , Feminino , Seguimentos , Humanos , Masculino , Pessoa de Meia-Idade , Percepção , Saliva/química , Política Antifumo/tendências , Fumar/epidemiologia , Fumar/psicologia , Inquéritos e Questionários , Poluição por Fumaça de Tabaco/análise
4.
J Oral Maxillofac Surg ; 74(11): 2128-2135, 2016 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-27528102

RESUMO

PURPOSE: To determine the effects on time, cost, and complication rates of integrating physician assistants (PAs) into the procedural components of an outpatient oral and maxillofacial surgery practice. MATERIALS AND METHODS: This is a prospective cohort study of patients from the Department of Plastic and Oral Surgery at Boston Children's Hospital who underwent removal of 4 impacted third molars with intravenous sedation in our outpatient facility. Patients were separated into the "no PA group" and PA group. Process maps were created to capture all activities from room preparation to patient discharge, and all activities were timed for each case. A time-driven activity-based costing method was used to calculate the average times and costs from the provider's perspective for each group. Complication rates were calculated during the periods for both groups. Descriptive statistics were calculated, and significance was set at P < .05. RESULTS: The total process time did not differ significantly between groups, but the average total procedure cost decreased by $75.08 after the introduction of PAs (P < .001). The time that the oral and maxillofacial surgeon was directly involved in the procedure decreased by an average of 19.2 minutes after the introduction of PAs (P < .001). No significant differences in postoperative complications were found. CONCLUSIONS: The addition of PAs into the procedural components of an outpatient oral and maxillofacial surgery practice resulted in decreased costs whereas complication rates remained constant. The increased availability of the oral and maxillofacial surgeon after the incorporation of PAs allows for more patients to be seen during a clinic session, which has the potential to further increase efficiency and revenue.


Assuntos
Dente Serotino/cirurgia , Procedimentos Cirúrgicos Bucais/economia , Assistentes Médicos/economia , Papel Profissional , Melhoria de Qualidade , Dente Impactado/cirurgia , Boston/epidemiologia , Controle de Custos , Eficiência , Feminino , Humanos , Masculino , Duração da Cirurgia , Complicações Pós-Operatórias/epidemiologia , Estudos Prospectivos , Salários e Benefícios/economia
5.
J Vasc Surg ; 61(2): 419-427.e1, 2015 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-25175629

RESUMO

OBJECTIVE: Wound complications negatively affect outcomes of lower extremity arterial reconstruction. By way of an investigator initiated clinical trial, we tested the hypothesis that a silver-eluting alginate topical surgical dressing would lower wound complication rates in patients undergoing open arterial procedures in the lower extremity. METHODS: The study block-randomized 500 patients at three institutions to standard gauze or silver alginate dressings placed over incisions after leg arterial surgery. This original operating room dressing remained until gross soiling, clinical need to remove, or postoperative day 3, whichever was first. Subsequent care was at the provider's discretion. The primary end point was 30-day wound complication incidence generally based on National Surgical Quality Improvement Program guidelines. Demographic, clinical, quality of life, and economic end points were also collected. Wound closure was at the surgeon's discretion. RESULTS: Participants (72% male) were 84% white, 45% were diabetic, 41% had critical limb ischemia, and 32% had claudication (with aneurysm, bypass revision, other). The overall 30-day wound complication incidence was 30%, with superficial surgical site infection as the most common. In intent-to-treat analysis, silver alginate had no effect on wound complications. Multivariable analysis showed that Coumadin (Bristol-Myers Squibb, Princeton, NJ; odds ratio [OR], 1.72; 95% confidence interval [CI], 1.03-2.87; P = .03), higher body mass index (OR, 1.05; 95% CI, 1.01-1.09; P = .01), and the use of no conduit/material (OR, 0.12; 95% CI, 0.82-3.59; P < .001) were independently associated with wound complications. CONCLUSIONS: The incidence of wound complications remains high in contemporary open lower extremity arterial surgery. Under the study conditions, a silver-eluting alginate dressing showed no effect on the incidence of wound complications.


Assuntos
Alginatos/administração & dosagem , Anti-Infecciosos Locais/administração & dosagem , Bandagens , Extremidade Inferior/irrigação sanguínea , Doença Arterial Periférica/cirurgia , Poliésteres/administração & dosagem , Polietilenos/administração & dosagem , Compostos de Prata/administração & dosagem , Procedimentos Cirúrgicos Vasculares/efeitos adversos , Administração Tópica , Idoso , Boston/epidemiologia , Distribuição de Qui-Quadrado , Feminino , Ácido Glucurônico/administração & dosagem , Ácidos Hexurônicos/administração & dosagem , Humanos , Incidência , Análise de Intenção de Tratamento , Modelos Logísticos , Masculino , Pessoa de Meia-Idade , Análise Multivariada , Razão de Chances , Doença Arterial Periférica/diagnóstico , Estudos Prospectivos , Infecção da Ferida Cirúrgica/epidemiologia , Infecção da Ferida Cirúrgica/prevenção & controle , Texas/epidemiologia , Fatores de Tempo , Resultado do Tratamento , Cicatrização/efeitos dos fármacos
6.
J Urban Health ; 91(4): 809-21, 2014 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-24272316

RESUMO

Tooth loss in adults diminishes quality of daily life, affecting eating, speaking, appearance, and social interactions. Tooth loss is linked to severe periodontitis and caries; and to risk of stroke, cardiovascular disease, rheumatoid arthritis, and dementia. At the national (USA) level, poverty and African-American race have been linked to lower utilization of dental services, suggesting that the 7.5 million residents of publicly supported housing may be at risk of tooth loss and poor overall oral health. We assessed whether residence in publicly supported housing in Boston was associated with four oral health-related indicators. Compared to residents of nonpublicly supported housing, after adjusting for covariates residents of both public housing developments (PHDs) and rental assistance units (RAUs) had significantly lower odds of having had a dental cleaning in the past year (PHD, OR = 0.64 (95 % CI, 0.44-0.93); RAU, OR = 0.67 (95 % CI, 0.45-0.99))-despite parity in having had a past year dental visit. Further, residents of RAUs had double the odds of having had six or more teeth removed (OR = 2.20 (95 % CI, 1.39-3.50)). Associations of race/ethnicity and housing type with dental insurance were interrelated. Unadjusted results document a deficit in oral health-related indicators among public housing residents, taken as a group, giving a clear picture of an oral health care gap and identifying a defined real-world population that could benefit from services. Existing public housing infrastructure could provide both a venue and a foundation for interventions to reduce oral health disparities on a broad scale.


Assuntos
Assistência Odontológica/estatística & dados numéricos , Inquéritos de Saúde Bucal/estatística & dados numéricos , Saúde Bucal/estatística & dados numéricos , Habitação Popular/estatística & dados numéricos , Saúde da População Urbana/estatística & dados numéricos , Adolescente , Adulto , Idoso , Idoso de 80 Anos ou mais , Boston/epidemiologia , Cárie Dentária/epidemiologia , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Prevalência , Fatores Socioeconômicos , Adulto Jovem
7.
Muscle Nerve ; 47(4): 488-92, 2013 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-23460299

RESUMO

INTRODUCTION: Given its association with Charcot-Marie-Tooth disease (CMT), pes cavus is a common reason for referral to a neurologist. We investigated clinical features that may predict CMT in children with pes cavus. METHODS: In this study we retrospectively reviewed pes cavus patients referred to Boston Children's Hospital in the past 20 years. Patients were categorized as idiopathic or CMT, based on EMG/genetic testing, and their clinical features were compared. RESULTS: Of the 70 patients studied, 33 had idiopathic pes cavus, and 37 had genetically confirmed CMT. Symptoms of weakness, unsteady gait, family history of pes cavus and CMT, and signs of sensory deficits, distal atrophy and weakness, absent ankle jerks, and gait abnormalities were associated with CMT. CONCLUSIONS: In children with pes cavus, certain clinical features can predict CMT and assist in selection of patients for further, potentially uncomfortable (EMG) and expensive (genetic) confirmatory investigations.


Assuntos
Doença de Charcot-Marie-Tooth/epidemiologia , Deformidades do Pé/epidemiologia , Adolescente , Boston/epidemiologia , Doença de Charcot-Marie-Tooth/diagnóstico , Doença de Charcot-Marie-Tooth/genética , Criança , Estudos de Coortes , Eletromiografia , Feminino , Deformidades do Pé/complicações , Deformidades do Pé/diagnóstico , Transtornos Neurológicos da Marcha/epidemiologia , Testes Genéticos , Humanos , Hipestesia/epidemiologia , Modelos Logísticos , Masculino , Debilidade Muscular/epidemiologia , Dor/epidemiologia , Estudos Retrospectivos
8.
BMC Musculoskelet Disord ; 12: 78, 2011 Apr 21.
Artigo em Inglês | MEDLINE | ID: mdl-21510880

RESUMO

BACKGROUND: Musculoskeletal disorders affect all racial and ethnic groups, including Hispanics. Because these disorders are not life-threatening, decision-making is generally preference-based. Little is known about whether Hispanics in the U.S. differ from non-Hispanic Whites with respect to key decision making preferences. METHODS: We assembled six focus groups of Hispanic and non-Hispanic White patients with chronic back or knee pain at an urban medical center to discuss management of their conditions and the roles they preferred in medical decision-making. Hispanic groups were further stratified by socioeconomic status, using neighborhood characteristics as proxy measures. Discussions were led by a moderator, taped, transcribed and analyzed using a grounded theory approach. RESULTS: The analysis revealed ethnic differences in several areas pertinent to medical decision-making. Specifically, Hispanic participants were more likely to permit their physician to take the predominant role in making health decisions. Also, Hispanics of lower socioeconomic status generally preferred to use non-internet sources of health information to make medical decisions and to rely on advice obtained by word of mouth. Hispanics emphasized the role of faith and religion in coping with musculoskeletal disability. The analysis also revealed broad areas of concordance across ethnic strata including the primary role that pain and achieving pain relief play in patients' experiences and decisions. CONCLUSIONS: These findings suggest differences between Hispanics and non-Hispanic Whites in preferred information sources and decision-making roles. These findings are hypothesis-generating. If confirmed in further research, they may inform the development of interventions to enhance preference-based decision-making among Hispanics.


Assuntos
Dor nas Costas/etnologia , Comportamento de Escolha , Conhecimentos, Atitudes e Prática em Saúde , Hispânico ou Latino/psicologia , Joelho/fisiopatologia , Dor/etnologia , Preferência do Paciente/etnologia , População Branca/psicologia , Adaptação Psicológica , Idoso , Idoso de 80 Anos ou mais , Dor nas Costas/psicologia , Dor nas Costas/terapia , Boston/epidemiologia , Doença Crônica , Características Culturais , Feminino , Grupos Focais , Humanos , Comportamento de Busca de Informação , Masculino , Pessoa de Meia-Idade , Dor/fisiopatologia , Dor/psicologia , Manejo da Dor , Medição da Dor , Papel do Médico , Relações Médico-Paciente , Pesquisa Qualitativa , Fatores Socioeconômicos
9.
Caries Res ; 44(5): 421-30, 2010.
Artigo em Inglês | MEDLINE | ID: mdl-20720422

RESUMO

Dental caries is caused by a combination of infection and diet. This disease, if left untreated, may lead to pain, and impair the quality of life, nutritional status and development of young children. The objective was to investigate the association between snacking and caries in a population at high risk of dental caries. American preschool children (n = 1,206) were recruited in the offices of paediatricians. Data on sociodemographic characteristics, oral hygiene, breast-feeding, use of bottle and snacking were collected by questionnaire. Plaque presence, the number of teeth and their caries status (deft) were scored. The children sampled were 61% Black, 27% White and 10% Asian. Of the 1- to 2-, 2- to 3- and 3- to 4-year-old children, 93.8, 82.4 and 77.3% were caries free, and their mean caries scores were 0.16, 0.58 and 0.93, respectively. Multivariate partial least squares (PLS) modelling revealed plaque presence, lowest income, descriptors for tooth exposure time (number of teeth and age) and cariogenic challenge (total intake of sugar-containing snacks and chips/crisps, and chips intake with a sugar-containing drink) to be associated with more caries. These differences were also found in univariate analyses; in addition, children who continued breast-feeding after falling asleep had significantly higher deft values than those who did not. PLS modelling revealed that eating chips clustered with eating many sweet snacks, candies, popcorn and ice cream. We conclude that, in addition to the traditional risk indicators for caries - presence of plaque, sugar intake and socioeconomic status -, consumption of chips was associated with caries in young children.


Assuntos
Cárie Dentária/epidemiologia , Comportamento Alimentar , Negro ou Afro-Americano/estatística & dados numéricos , Asiático/estatística & dados numéricos , Bebidas/estatística & dados numéricos , Boston/epidemiologia , Alimentação com Mamadeira/estatística & dados numéricos , Aleitamento Materno/estatística & dados numéricos , Doces/estatística & dados numéricos , Pré-Escolar , Estudos de Coortes , Índice CPO , Placa Dentária/epidemiologia , Sacarose Alimentar/administração & dosagem , Escolaridade , Fast Foods/estatística & dados numéricos , Feminino , Humanos , Sorvetes/estatística & dados numéricos , Renda/estatística & dados numéricos , Lactente , Masculino , Higiene Bucal/estatística & dados numéricos , Pais/educação , Fatores de Risco , Classe Social , População Branca/estatística & dados numéricos
10.
Angle Orthod ; 80(3): 440-5, 2010 May.
Artigo em Inglês | MEDLINE | ID: mdl-20050734

RESUMO

OBJECTIVE: To test the null hypothesis that there is no relationship between infraocclusion and the occurrence of other dental anomalies in subjects selected for clear-cut infraocclusion of one or more deciduous molars. MATERIALS AND METHODS: The experimental sample consisted of 99 orthodontic patients (43 from Boston, Mass, United States; 56 from Jerusalem, Israel) with at least one deciduous molar in infraocclusion greater than 1 mm vertical discrepancy, measured from the mesial marginal ridge of the first permanent molar. Panoramic radiographs and dental casts were used to determine the presence of other dental anomalies, including agenesis of permanent teeth, microdontia of maxillary lateral incisors, palatally displaced canines (PDC), and distal angulation of the mandibular second premolars (MnP2-DA). Comparative prevalence reference values were utilized and statistical testing was performed using the chi-square test (P < .05) and odds ratio. RESULTS: The studied dental anomalies showed two to seven times greater prevalence in the infraocclusion samples, compared with reported prevalence in reference samples. In most cases, the infraoccluded deciduous molar exfoliated eventually and the underlying premolar erupted spontaneously. In some severe phenotypes (10%), the infraoccluded deciduous molar was extracted and space was regained to allow uncomplicated eruption of the associated premolar. CONCLUSION: Statistically significant associations were observed between the presence of infraocclusion and the occurrence of tooth agenesis, microdontia of maxillary lateral incisors, PDC, and MnP2-DA. These associations support a hypothesis favoring shared causal genetic factors. Clinically, infraocclusion may be considered an early marker for the development of later appearing dental anomalies, such as tooth agenesis and PDC.


Assuntos
Má Oclusão/epidemiologia , Dente Molar/patologia , Anormalidades Dentárias/epidemiologia , Dente Decíduo/patologia , Adolescente , Anodontia/epidemiologia , Dente Pré-Molar/patologia , Boston/epidemiologia , Criança , Dente Canino/patologia , Feminino , Humanos , Incisivo/anormalidades , Israel/epidemiologia , Masculino , Modelos Dentários , Fenótipo , Prevalência , Radiografia Panorâmica , Estudos Retrospectivos , Erupção Dentária/fisiologia , Erupção Ectópica de Dente/epidemiologia
11.
J Public Health Dent ; 69(3): 156-62, 2009.
Artigo em Inglês | MEDLINE | ID: mdl-19192100

RESUMO

OBJECTIVES: The aims of this study were to compare prevalence of early childhood caries (ECC) in 1- to 3-year-old children seeing primary-care pediatricians at two urban medical centers in Boston to the prevalence of ECC in similarly aged US children surveyed as part of the Third National Health and Nutrition Examination Survey (NHANES III) and to assess risk factors for ECC among this cohort of children compared with risk factors among similarly aged US children. METHODS: Characteristics of 787 1- to 3-year-old children from two urban Boston medical centers were compared with those of 3,644 similarly aged US children surveyed as part of NHANES III. Demographic and social characteristics and ECC prevalence by putative risk factors were compared. A multiple logistic regression model was fit to assess putative risk factors and difference between groups simultaneously. RESULTS: Race, age, previous dental visit, parents' education, and household income were significantly associated with ECC prevalence. Parents' place of birth was a significant effect modifier with lower ECC among Boston children of immigrants than among US children of immigrants. CONCLUSIONS: Lower ECC prevalence among urban Boston children of immigrant parents compared with US children of immigrant parents may reflect changing immigrant composition in the United States since NHANES III or a different immigrant composition in the Boston area compared with the United States. This finding reinforces the need for further research of immigrants in order to understand cultural practices that may affect oral health. Finally, low ECC prevalence among very young children reinforces the importance of early intervention in reducing ECC.


Assuntos
Cárie Dentária/epidemiologia , Fatores Etários , Boston/epidemiologia , Pré-Escolar , Índice CPO , Assistência Odontológica/estatística & dados numéricos , Escolaridade , Emigrantes e Imigrantes/estatística & dados numéricos , Etnicidade/estatística & dados numéricos , Feminino , Disparidades nos Níveis de Saúde , Humanos , Renda , Lactente , Modelos Logísticos , Masculino , Prevalência , Fatores de Risco , Classe Social , Estados Unidos/epidemiologia , População Urbana/estatística & dados numéricos
12.
J Craniofac Surg ; 20(5): 1375-7, 2009 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-19816260

RESUMO

The frequency of associated cleft palate is known to be high in some fibroblast growth factor receptor 2 (FGFR2)-mediated craniosynostosis syndromes, such as Apert syndrome. However, there is little information on the frequency of palatal clefts in the FGFR2-mediated disorder, that is, Pfeiffer syndrome. The purpose of this study was to determine the frequency of palatal clefts in patients with Pfeiffer syndrome. The records of patients with Pfeiffer syndrome managed in our craniofacial unit were reviewed. Only patients with a confirmed diagnosis of Pfeiffer syndrome were included. Diagnostic criteria were as follows: characteristic mutations in FGFR1 or FGFR2 or, in the absence of genetic testing, clinical findings consistent with Pfeiffer syndrome as determined by a clinical geneticist or our most experienced surgeon (J.B.M.). Only 2 clefts were noted in 25 patients (8%), including 1 with a submucous cleft and 1 with an overt palatal cleft. Many patients (87%) were described as having a high-arched and narrow palate, and 1 had a low, broad palate. Nine patients were noted to have choanal atresia or stenosis. Clefting of the palate does occur in Pfeiffer syndrome but at a low frequency.


Assuntos
Acrocefalossindactilia/epidemiologia , Fissura Palatina/epidemiologia , Acrocefalossindactilia/genética , Boston/epidemiologia , Atresia das Cóanas/epidemiologia , Feminino , Testes Genéticos , Humanos , Masculino , Mutação/genética , Palato/anormalidades , Receptor Tipo 1 de Fator de Crescimento de Fibroblastos/genética , Receptor Tipo 2 de Fator de Crescimento de Fibroblastos/genética , Estudos Retrospectivos , Insuficiência Velofaríngea/epidemiologia
13.
Pediatr Emerg Care ; 25(12): 819-22, 2009 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-19952970

RESUMO

OBJECTIVES: Holiday ornament injuries in children have not been well documented in the medical literature. Our aim was to investigate the patterns of injuries sustained from these ornaments as a first measure toward prevention. METHODS: This was a retrospective cohort analysis of all patients examined in an urban pediatric emergency department over a 13-year period ending in March 2008 for holiday ornament-related injuries. Cases were identified using a computer-assisted text query followed by a manual chart review. Data collected from each chart included the child's age, sex, injury characteristics, physical examination findings, radiographic imaging, interventions, and disposition. To analyze injury rates over the years, we used a multiplicative Poisson model allowing varying exposures. RESULTS: Over the study period, we identified 76 eligible patients. The median age was 2 years (interquartile range, 1.17-3.3 years); 44.7% were female. Forty-three of the 76 cases (53.9%) involved ingestions: 35 were of holiday ornaments, and 8 were of light bulbs. All but one of these ornaments were made of glass. In 28%, there was an associated bleed either from the mouth or as a delayed gastrointestinal bleed. Other patients experienced lacerations (27.6%), eye injuries (5.1%), and minor electrocution injury (2.5%). Imaging was performed in 85%. A subspecialty consult was obtained in 23%, primarily addressing a foreign body ingestion or removal after skin exploration. The incidence rate has not changed over the years. CONCLUSIONS: Holiday ornament-related injuries primarily involve foreign body ingestions and glass-related injuries. Over half of the injuries involved small light bulbs and ornaments made of glass placed at the level a toddler can reach. Pediatricians are advised to discuss these points with families during holiday season.


Assuntos
Férias e Feriados , Ferimentos e Lesões/epidemiologia , Acidentes Domésticos/prevenção & controle , Acidentes Domésticos/estatística & dados numéricos , Adolescente , Boston/epidemiologia , Criança , Pré-Escolar , Serviço Hospitalar de Emergência/estatística & dados numéricos , Feminino , Corpos Estranhos/epidemiologia , Vidro , Humanos , Incidência , Lactente , Lacerações/epidemiologia , Masculino , Distribuição de Poisson , Estudos Retrospectivos , Ferimentos e Lesões/prevenção & controle , Adulto Jovem
14.
Pediatr Emerg Care ; 25(10): 645-7, 2009 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-21465690

RESUMO

BACKGROUND: Glass mercury thermometers were once used as the criterion standard for measuring core body temperature. Once broken, however, there is the dual hazard of broken glass and exposure to mercury. Previous studies have focused only on the mercury hazard rather than injuries related to thermometer glass. OBJECTIVE: To identify injury patterns from glass thermometers, including glass-related injury and mercury exposure. METHODS: We performed a retrospective cohort study of glass thermometer-related injuries in children evaluated in a pediatric emergency department between October 1995 and October 2007. Case identification was performed using a computer-assisted screening tool followed by a manual chart review. Collected data included age, sex, injury characteristics, physical examination findings, radiologic imaging, interventions, and disposition. To analyze injury rates during these years, we used a multiplicative Poisson model allowing for varying exposures. RESULTS: Thirty-three patients were identified among 627,592 who presented to the emergency department during the study period. Approximately 1 to 6 patients presented every year, including 3 patients in 2007. Decline in injury incidence is less than 9% per year (P = 0.041). Median patient age was 2.4 years (interquartile range, 0.4-3.8 years); 12 patients (36%) were female. Twenty-two patients (66%) underwent radiologic imaging to identify potential foreign body (21 underwent radiography and 1 underwent computed tomographic scanning). There were 15 mouth injuries (45%), 13 anal injuries (39%), and 1 ear injury. Glass was identified by imaging in 5 patients (15%) and by sigmoidoscopic evaluation in 1 patient (3%). Mercury exposure was identified in 14 patients (42%). CONCLUSIONS: Persistent use of glass mercury thermometers has resulted in pediatric injury especially in children younger than 4 years. We reported the different mechanisms of injury with the hope of eliminating its use and reinforcing the use of alternative thermometers.


Assuntos
Vidro , Mercúrio/toxicidade , Termômetros/efeitos adversos , Ferimentos e Lesões/epidemiologia , Ferimentos e Lesões/etiologia , Boston/epidemiologia , Criança , Pré-Escolar , Feminino , Corpos Estranhos/epidemiologia , Corpos Estranhos/etiologia , Humanos , Incidência , Masculino , Distribuição de Poisson , Estudos Retrospectivos
15.
J Public Health Dent ; 68(1): 7-13, 2008.
Artigo em Inglês | MEDLINE | ID: mdl-18179469

RESUMO

OBJECTIVES: To compare the prevalence of caries between rural and urban children with unmet dental health needs who participated in the New England Children's Amalgam Trial. METHODS: Baseline tooth and surface caries were clinically assessed in children from rural Maine (n = 243) and urban Boston (n = 291), who were aged 6 to 10 years, with two or more posterior carious teeth and no previous amalgam restorations. Statistical analyses used negative binomial models for primary dentition caries and zero-inflated models for permanent dentition caries. RESULTS: Urban children had a higher mean number of carious primary surfaces (8.5 versus 7.4) and teeth (4.5 versus 3.9) than rural children. The difference remained statistically significant after adjusting for sociodemographic factors and toothbrushing frequency. In permanent dentition, urban children were approximately three times as likely to have any carious surfaces or teeth. However, rural/urban dwelling was not statistically significant in the linear analysis of caries prevalence among children with any permanent dentition caries. Covariates that were statistically significant in all models were age and number of teeth. Toothbrushing frequency was also important for permanent teeth. CONCLUSIONS: Within this population of New England children with unmet oral health needs, significant differences were apparent between rural and urban children in the extent of untreated dental decay. Results indicate that families who agree to participate in programs offering reduced cost or free dental care may present with varying amounts of dental need based on geographic location.


Assuntos
Cárie Dentária/epidemiologia , Disparidades nos Níveis de Saúde , Saúde da População Rural/estatística & dados numéricos , Saúde da População Urbana/estatística & dados numéricos , Boston/epidemiologia , Criança , Resinas Compostas , Amálgama Dentário , Restauração Dentária Permanente/métodos , Dentição Permanente , Feminino , Fluoretação , Necessidades e Demandas de Serviços de Saúde/estatística & dados numéricos , Humanos , Maine/epidemiologia , Masculino , Modelos Estatísticos , Prevalência , Ensaios Clínicos Controlados Aleatórios como Assunto , Dente Decíduo
16.
J Public Health Dent ; 68(1): 14-21, 2008.
Artigo em Inglês | MEDLINE | ID: mdl-18179466

RESUMO

OBJECTIVES: Previous research shows increased dental decay among immigrants, but little is known about the oral health of the growing population of children of immigrants. We compared the children of immigrants to the children of US-born caregivers in their caries experience at enrollment and their new caries increments during the 5-year New England Children's Amalgam Trial (NECAT). METHODS: NECAT recruited 283 Boston-area children aged 6 to 10 with untreated caries and offered free semiannual preventive and restorative dental care during the trial. Sociodemographic factors and caregiver immigrant status were assessed through interviews. Multivariate negative binomial models evaluated the association between caregiver immigrant status and clinically assessed carious surfaces. RESULTS: Forty percent of these Boston-area children had immigrant caregivers. At baseline, the children of immigrants had more carious surfaces (11.5 versus 9.4, adjusted for race/ethnicity, age, gender, and caregiver smoking status). Caregiver language preference explained some of this association. Immigrant status and language preference were not associated with 5-year caries increments. CONCLUSIONS: Prevalent disparities in the unmet dental needs of the immigrants' children were quickly ameliorated during participation in NECAT Dental initiatives that target neighborhoods and are sensitive to acculturation levels may help improve and maintain the oral health of immigrant families.


Assuntos
Cárie Dentária/epidemiologia , Emigrantes e Imigrantes/estatística & dados numéricos , Disparidades nos Níveis de Saúde , Boston/epidemiologia , Criança , Resinas Compostas , Assistência Odontológica Integral/economia , Demografia , Amálgama Dentário , Restauração Dentária Permanente/métodos , Feminino , Seguimentos , Humanos , Incidência , Idioma , Masculino , Modelos Estatísticos , Prevalência , Estudos Prospectivos , Ensaios Clínicos Controlados Aleatórios como Assunto , Fatores Socioeconômicos
17.
Pediatr Dent ; 30(5): 388-92, 2008.
Artigo em Inglês | MEDLINE | ID: mdl-18942597

RESUMO

PURPOSE: The purpose of this study was to assess the relationship between baseline caries experience and the restoration replacement rate in children. METHODS: The 5-year New England Children's Amalgam Trial recruited 534 6- to 10-year-old children with 2 or more carious posterior teeth. The association between decoy and longevity of restorations was assessed. Restorations with no follow-up (N = 391) were excluded from analysis. RESULTS: The average follow-up was 3.0 +/- 1.6 years in 489 children. Restorations with follow-up (N = 3,604) were placed in mouths with a median of 15 dfs/DFS and 8 dft/DFT. The need for replacement increased significantly (P < or = .001) with increasing numbers of dfs/DFS and dft/DFT. After 5 years of follow-up, at least 15% of restorations in a mouth with > or = 14 dfs/DFS needed replacement, compared to 9% for 2 to 5 dfs/DFS. Comparing dft/DFT after 5 years of follow-up, there was a 23% replacement rate for > or = 12 dft/DFT compared to 10% for 2 to 3 dft/DFT. Decoy in the mouth had a greater association with the need for replacement due to new caries compared to replacement due to recurrent caries. CONCLUSION: Children with more decoy at the time of restoration placement were at higher risk for replacement of restorations.


Assuntos
Cárie Dentária/epidemiologia , Restauração Dentária Permanente/estatística & dados numéricos , Boston/epidemiologia , Criança , Compômeros , Resinas Compostas , Índice CPO , Amálgama Dentário , Materiais Dentários , Falha de Restauração Dentária , Seguimentos , Necessidades e Demandas de Serviços de Saúde/estatística & dados numéricos , Humanos , Maine/epidemiologia , Recidiva , Retratamento , Fatores de Risco , Saúde da População Rural/estatística & dados numéricos , Análise de Sobrevida , Dente Decíduo/patologia , Saúde da População Urbana/estatística & dados numéricos
18.
Pediatrics ; 141(Suppl 1): S30-S39, 2018 01.
Artigo em Inglês | MEDLINE | ID: mdl-29292304

RESUMO

BACKGROUND: Tobacco use inflicts a disproportionate burden of disease on people of color. We evaluated the reach among African American and Hispanic smokers in Boston of 2 referral strategies to the Massachusetts quitline: (1) a provider-referred strategy based in pediatric and dental clinics and (2) a targeted media campaign to promote self-referral to the quitline. METHODS: Selected demographic characteristics of Boston quitline participants during the study period (2010-2012) were compared between strategies. Self-referred smoker characteristics were also compared in the years before and after the media campaign. Finally, the characteristics of quitline participants were compared with smokers in the 2010 Boston Behavioral Risk Factor Surveillance Survey. RESULTS: During the study period, 4066 smokers received cessation services from the quitline; 3722 (91.5%) were self-referred, and 344 (8.5%) were referred by pediatric and dental providers. The proportion of black (31.6%) and Hispanic (20.3%) participants referred by providers was higher than among self-referred participants (18.3% and 7.8%, respectively; P <.001). Overall, provider-referred participants were less likely to be white (17.9%) than to be people of color. Self-referred smokers were more likely to be white (68.0%) than the estimated population of Boston smokers overall (62.9%; P <.001). CONCLUSIONS: The large-scale media campaign, which promoted self-referral, was associated with higher quitline participation overall, but the provider-referred strategy based in community health centers yielded participation from a greater proportion of smokers of color. The 2 strategies reached different subpopulations of smokers, and their combined reach enhanced access to cessation services among smokers from different racial and ethnic backgrounds.


Assuntos
Negro ou Afro-Americano/estatística & dados numéricos , Hispânico ou Latino/estatística & dados numéricos , Linhas Diretas , Encaminhamento e Consulta , Prevenção do Hábito de Fumar/métodos , Fumar Tabaco/etnologia , Adolescente , Adulto , Idoso , Boston/epidemiologia , Estudos Transversais , Escolaridade , Feminino , Humanos , Cobertura do Seguro , Seguro Saúde , Masculino , Pessoa de Meia-Idade , Prevalência , População Branca/estatística & dados numéricos , Adulto Jovem
20.
J Public Health Dent ; 67(3): 171-3, 2007.
Artigo em Inglês | MEDLINE | ID: mdl-17899903

RESUMO

OBJECTIVES: We compared the periodontal disease levels in a population of low socioeconomic status (SES), urban, adult, Chinese American immigrants with and without type 2 diabetes. METHODS: Dental records of 51 diabetic adults were compared with 102 nondiabetic controls from South Cove Community Health Center, Boston, MA, cross-matched by age and gender. RESULTS: Our results showed that the proportion of sites with bone loss greater than 5 mm in the mesial areas of teeth was significantly correlated with higher glycosylated hemoglobin (HbA1c) (r = 0.35, P-value = 0.01). The number of teeth with mesial bone loss of greater than 5 mm was correlated to increasing HbA1c (r = 0.37, P-value = 0.01). CONCLUSIONS: Our preliminary data showed that mesial bone loss greater than 5 mm was correlated with inadequate control of diabetes. The implications and recommendations for the dental care of immigrant Chinese Americans with diabetes were discussed.


Assuntos
Perda do Osso Alveolar/etiologia , Diabetes Mellitus Tipo 2/complicações , Perda de Dente/etiologia , Idoso , Perda do Osso Alveolar/epidemiologia , Asiático/estatística & dados numéricos , Boston/epidemiologia , China/etnologia , Diabetes Mellitus Tipo 2/sangue , Emigração e Imigração , Feminino , Hemoglobinas Glicadas/análise , Humanos , Masculino , Estudos Retrospectivos , Classe Social , Perda de Dente/epidemiologia , População Urbana
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