The P2X7 Receptor.
Adv Exp Med Biol
; 1051: 17-53, 2017.
Artigo em Inglês | MEDLINE | ID: mdl-28676924
Contribution of the Juxtatransmembrane Intracellular Regions to the Time Course and Permeation of ATP-gated P2X7 Receptor Ion Channels.
Localization of the gate and selectivity filter of the full-length P2X7 receptor.
Dual gating mechanism and function of P2X7 receptor channels.
Full-Length P2X<sub>7</sub> Structures Reveal How Palmitoylation Prevents Channel Desensitization.
A rare P2X7 variant Arg307Gln with absent pore formation function protects against neuroinflammation in multiple sclerosis.
Mapping the Site of Action of Human P2X7 Receptor Antagonists AZ11645373, Brilliant Blue G, KN-62, Calmidazolium, and ZINC58368839 to the Intersubunit Allosteric Pocket.
Altered donor P2X7 activity in human leukocytes correlates with P2RX7 genotype but does not affect the development of graft-versus-host disease in humanised mice.
Ca<sup>2+</sup> flux through splice variants of the ATP-gated ionotropic receptor P2X7 is regulated by its cytoplasmic N terminus.
Regulation of adult neural progenitor cell functions by purinergic signaling.
The purinergic receptor P2RX7 directs metabolic fitness of long-lived memory CD8<sup>+</sup> T cells.