The periodontal-cardiovascular link.
Compend Contin Educ Dent
; 25(9): 681-2, 685-92; quiz 694, 2004 Sep.
Article
en En
| MEDLINE
| ID: mdl-15645898
Cardiovascular disease (CVD) and periodontitis are common chronic conditions, and the former remains a major contributor to human mortality. Recent attention has focused on a potential link between periodontal disease and CVD. Observational studies consistently indicate that people with destructive periodontitis may be 1.3 to 2 times more likely to have CVD. This association appears to be biologically plausible, and investigations in atherosclerosis animal models demonstrate larger atheroma sizes in animals infected with the periodontal pathogen, Porphyromonas gingivalis, compared with control animals. Although direct intervention data on the effects of periodontal therapy on CVD risk in patients are not currently available, indirect data suggest that mechanical periodontal therapy can decrease surrogate cardiovascular markers such as serum C-reactive protein. After a recent systematic review on the periodontal-cardiovascular link, a consensus panel concluded that patients and clinicians should be informed that periodontal therapy may prevent the onset or progression of CVD.
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Banco de datos:
MEDLINE
Asunto principal:
Periodontitis
/
Enfermedades Cardiovasculares
Tipo de estudio:
Observational_studies
/
Prognostic_studies
/
Systematic_reviews
Límite:
Animals
/
Female
/
Humans
/
Male
Idioma:
En
Revista:
Compend Contin Educ Dent
Año:
2004
Tipo del documento:
Article
País de afiliación:
Estados Unidos