Histomorphometric study of the periodontal ligament in the initial period of orthodontic movement in Wistar rats with induced allergic asthma.
Am J Orthod Dentofacial Orthop
; 142(3): 333-8, 2012 Sep.
Article
en En
| MEDLINE
| ID: mdl-22920699
ABSTRACT
INTRODUCTION:
Asthma is a common systemic disease occurring in infancy and adolescence, time periods that could encompass orthodontic treatment. Asthma is an inflammatory disease; therefore, it might interfere with orthodontic tooth movement. The purpose of the study was to analyze the histomorphologic aspects of the periodontal ligament of asthmatic Wistar rats in the initial period of orthodontic movement.METHODS:
Thirty-two Wistar rats were divided into 4 groups 2 control groups consisting of rats without induced allergic asthma, and 2 experimental groups consisting of rats with induced allergic asthma. The animals of the first control and experimental groups did not receive orthodontic forces, whereas those in the second control and experimental groups were subjected to mesial movement of the maxillary left first molar for 3 days. The samples were prepared for histomorphometric analysis of the periodontal ligament. The area of the periodontal ligament was calculated as a function of root length in the cervical and apical regions of the distal face of the maxillary first molar mesial root. The Student t test and the Welch correlation test were applied to the data obtained.RESULTS:
There was a statistically significant difference (P <0.05) between the control and experimental groups. An enhanced response to orthodontic force was observed in the asthmatic animals the periodontal ligament was more compressed at the pressure area and more stretched in the traction area.CONCLUSIONS:
Our findings indicate that experimental allergic asthma seems to exacerbate orthodontic movement in rats.
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Ligamento Periodontal
/
Asma
/
Técnicas de Movimiento Dental
/
Análisis del Estrés Dental
Límite:
Animals
Idioma:
En
Revista:
Am J Orthod Dentofacial Orthop
Asunto de la revista:
ODONTOLOGIA
/
ORTODONTIA
Año:
2012
Tipo del documento:
Article
País de afiliación:
Brasil