Solidification drug nanosuspensions into nanocrystals by freeze-drying: a case study with ursodeoxycholic acid.

Ma, Yue-Qin; Zhang, Zeng-Zhu; Li, Gang; Zhang, Jing; Xiao, Han-Yang; Li, Xian-Fei

Ma, Yue-Qin; Zhang, Zeng-Zhu; Li, Gang; Zhang, Jing; Xiao, Han-Yang; Li, Xian-Fei.

Afiliación

Ma YQ; a Department of Pharmaceutics , the 94th Hospital of People's Liberation Army , Nanchang , China.
Zhang ZZ; a Department of Pharmaceutics , the 94th Hospital of People's Liberation Army , Nanchang , China.
Li G; a Department of Pharmaceutics , the 94th Hospital of People's Liberation Army , Nanchang , China.
Zhang J; a Department of Pharmaceutics , the 94th Hospital of People's Liberation Army , Nanchang , China.
Xiao HY; a Department of Pharmaceutics , the 94th Hospital of People's Liberation Army , Nanchang , China.
Li XF; a Department of Pharmaceutics , the 94th Hospital of People's Liberation Army , Nanchang , China.

Pharm Dev Technol ; 21(2): 180-8, 2016 Mar.

Article en En | MEDLINE | ID: mdl-25427602

Asunto(s)

Nanopartículas/química; Suspensiones/química; Ácido Ursodesoxicólico/química; Cristalización/métodos; Composición de Medicamentos/métodos; Estabilidad de Medicamentos; Liofilización/métodos; Congelación; Glucosa/química; Derivados de la Hipromelosa/química; Sacarosa/química; Temperatura

Palabras clave

Freeze-drying; nanocrystals; solidification stress; ursodeoxycholic acid

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Suspensiones / Ácido Ursodesoxicólico / Nanopartículas Idioma: En Revista: Pharm Dev Technol Asunto de la revista: FARMACIA Año: 2016 Tipo del documento: Article País de afiliación: China

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