Building biomedical materials using photochemical bond cleavage.
Adv Mater
; 27(10): 1647-62, 2015 Mar 11.
Article
en En
| MEDLINE
| ID: mdl-25655424
ABSTRACT
Light can be used as an external trigger to precisely determine where and when a process is initiated as well as how much of the process is being consumed. Phototriggers are a type of photoresponsive functional group that undergo an irreversible photolysis reaction by selectively breaking a chemical bond, enabling three fundamental functions the photoactivation of fluorescent and bioactive molecules; the photocleavable degradation of macromolecular materials; and the photorelease of drugs, active groups, or surface charges from carriers and interfaces. With the expanded applications of light-controlled technology, particularly in living systems, new challenges and improvements of phototriggers are required to fulfill the demands for better sensitivity, faster kinetics, and more-demanding biomedical applications. Here, improvements to several conventional phototriggers are highlighted, and their notable, representative biomedical applications and their challenges are discussed.
Palabras clave
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Fotólisis
/
Materiales Biocompatibles
Idioma:
En
Revista:
Adv Mater
Asunto de la revista:
BIOFISICA
/
QUIMICA
Año:
2015
Tipo del documento:
Article
País de afiliación:
China