Restoring Endogenous Repair Mechanisms to Heal Chronic Wounds with a Multifunctional Wound Dressing.
Mol Pharm
; 18(8): 3171-3180, 2021 08 02.
Article
en En
| MEDLINE
| ID: mdl-34279974
ABSTRACT
Current treatment of chronic wounds has been critically limited by various factors, including bacterial infection, biofilm formation, impaired angiogenesis, and prolonged inflammation. Addressing these challenges, we developed a multifunctional wound dressing-based three-pronged approach for accelerating wound healing. The multifunctional wound dressing, composed of nanofibers, functional nanoparticles, natural biopolymers, and selected protein and peptide, can target multiple endogenous repair mechanisms and represents a promising alternative to current wound healing products.
Palabras clave
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Péptidos
/
Infecciones Estafilocócicas
/
Staphylococcus aureus
/
Vendajes
/
Cicatrización de Heridas
/
Infección de Heridas
/
Anexina A1
/
Proteínas Relacionadas con la Folistatina
/
Diabetes Mellitus Experimental
/
Herida Quirúrgica
Límite:
Animals
/
Humans
/
Male
Idioma:
En
Revista:
Mol Pharm
Asunto de la revista:
BIOLOGIA MOLECULAR
/
FARMACIA
/
FARMACOLOGIA
Año:
2021
Tipo del documento:
Article
País de afiliación:
España