Association of tooth count with cognitive decline and dementia in the Finnish adult population.
J Clin Periodontol
; 50(9): 1154-1166, 2023 09.
Article
en En
| MEDLINE
| ID: mdl-37461219
ABSTRACT
AIM:
To evaluate whether tooth loss is associated with cognitive decline and incident dementia. MATERIALS ANDMETHODS:
We analysed data from the Finnish population-based Health 2000 and follow-up Health 2011 surveys (participants aged ≥30 years and without dementia at baseline; N = 5506 at baseline and 3426 at 11-year follow-up). Dementia diagnoses until 2015 were ascertained from national registers (N = 5542). Tooth count was dichotomized as adequate (≥20) versus tooth loss (<20). Tooth loss was further stratified into 10-19 teeth, 1-9 teeth and edentulism. Upper and lower jaws were also considered separately. Baseline cognitive test scores were dichotomized by median as high versus low, and 11-year change as decline versus no decline.RESULTS:
Tooth loss (<20) was associated with lower baseline overall cognition (odds ratio [OR] = 1.21, 95% confidence interval [CI] = 1.03-1.43), 11-year cognitive decline (OR = 1.30, 95% CI = 1.05-1.70) and higher 15-year dementia risk (hazard ratio = 1.52, 95% CI = 1.15-2.02) after adjusting for multiple confounders. After adjustment for dentures, associations became non-significant, except for 10-19 teeth remaining and dementia. Results were similar after considering reverse causality bias; however, 10-19 teeth remaining was significantly associated with 11-year cognitive decline even after adjustment for dentures. No jaw-specific differences were observed.CONCLUSIONS:
Tooth loss adversely impacts the risk of cognitive decline and dementia. The role of dentures should be further explored.Palabras clave
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Pérdida de Diente
/
Demencia
/
Disfunción Cognitiva
Tipo de estudio:
Etiology_studies
/
Risk_factors_studies
Límite:
Adult
/
Humans
País/Región como asunto:
Europa
Idioma:
En
Revista:
J Clin Periodontol
Año:
2023
Tipo del documento:
Article
País de afiliación:
Finlandia