Heat shock proteins in the human periodontal disease process.
Microbiol Immunol
; 39(5): 321-7, 1995.
Article
en En
| MEDLINE
| ID: mdl-7565172
ABSTRACT
The production of HSP by periodontopathic Gram-negative bacteria was examined by SDS-PAGE, two dimensional gel electrophoresis, and Western blotting using monoclonal antibodies against HSPs. Strains of Actinobacillus actinomycetemcomitans, Eikenella corrodens, Fusobacterium nucleatum, Prevotella intermedia, Prevotella nigrescens, Prevotella melaninogenica, and Treponema socranskii species produced HSP which reacted with anti-Yersinia enterocolitica HSP 60 and/or mycobacterial 65-kDA HSP monoclonal antibodies. It found that gingival homogenate samples from patients with adult periodontitis reacted with anti-human HSP were also found in a serum sample from a periodontitis patient. The present study suggests that HSPs are implicated in human periodontal disease process.
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Banco de datos:
MEDLINE
Asunto principal:
Periodontitis
/
Proteínas Bacterianas
/
Bacterias Gramnegativas
/
Proteínas de Choque Térmico
Límite:
Adult
/
Animals
/
Humans
Idioma:
En
Revista:
Microbiol Immunol
Año:
1995
Tipo del documento:
Article
País de afiliación:
Japón