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Tara Gum as a Controlled Delivery System of Fluoride in Toothpaste: In Vitro Enamel Remineralization Study
Department of Clinic and Social DentistryFernandes, Nayanna Lana Soares; Department of Prosthesis and PeriodonticsMeira, Ingrid Andrade; Department of Clinic and Social DentistryAlves, Vanessa Feitosa; Department of Clinic and Social DentistrySampaio, Fabio Correia; Department of MorphologyOliveira, Andressa Feitosa Bezerra de.
Afiliação
  • Department of Clinic and Social DentistryFernandes, Nayanna Lana Soares; Federal University of Paraíba. School of Dentistry. Department of Clinic and Social DentistryFernandes, Nayanna Lana Soares. João Pessoa. BR
  • Department of Prosthesis and PeriodonticsMeira, Ingrid Andrade; University of Campinas. Piracicaba Dental School. Department of Prosthesis and PeriodonticsMeira, Ingrid Andrade. Piracicaba. BR
  • Department of Clinic and Social DentistryAlves, Vanessa Feitosa; Federal University of Paraíba. School of Dentistry. Department of Clinic and Social DentistryAlves, Vanessa Feitosa. João Pessoa. BR
  • Department of Clinic and Social DentistrySampaio, Fabio Correia; Federal University of Paraíba. School of Dentistry. Department of Clinic and Social DentistrySampaio, Fabio Correia. João Pessoa. BR
  • Department of MorphologyOliveira, Andressa Feitosa Bezerra de; Federal University of Paraíba. School of Dentistry. Department of MorphologyOliveira, Andressa Feitosa Bezerra de. João Pessoa. BR
Article em En | LILACS, BBO | ID: biblio-1143387
Biblioteca responsável: BR1264.1
ABSTRACT
ABSTRACT

Objective:

To evaluate the remineralizing potential of a hydrocolloid-based, controlled fluoride-releasing system added to dentifrice formulas. Material and

Methods:

Sixty-five human enamel blocks were prepared and the surface microhardness (SH0) values were determined. The artificial caries lesions were induced and the demineralization surface microhardness (SH1) was evaluated. The blocks were randomly allocated into five groups (n = 13) (1) 100-TGF (100% NaF with Tara gum added); (2) 50-TGF (50% free NaF + 50% NaF with Tara gum added); (3) 100% TG (100% Tara gum without fluoride); (4) 100% NaF (positive control); and (5) placebo (without Tara gum and NaF). The blocks were submitted to 7 days pH cycling and treated with dentifrice slurries twice a day. Finally, surface hardness (SH2) was assessed and the percentage of surface hardness recovery (%SMHR) was calculated. Analysis of variance (ANOVA) followed by Bonferroni test was used for statistical analysis.

Results:

A positive %SMHR was found in the 100% NaF (5.07) and 50-TGF (0.64) groups, while the 100-TGF (-1.38), 100% TG (-3.88) and placebo (-0.52) did not undergo remineralization. Statistically significant differences were observed between 100% NaF and all the groups except for 50-TGF (p<0.05).

Conclusion:

The presence of hydrocolloid (Tara gum) promoted minimal remineralization when associated with NaF. In the applied model, Tara gum may have compromised remineralization, preventing free fluoride from acting effectively in the carious lesion.
Assuntos
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Texto completo: 1 Base de dados: BBO / LILACS Assunto principal: Remineralização Dentária / Cremes Dentais / Materiais Biomédicos e Odontológicos / Técnicas In Vitro / Fluoretos Tipo de estudo: Clinical_trials / Evaluation_studies Limite: Humans País/Região como assunto: America do sul / Brasil Idioma: En Revista: Pesqui. bras. odontopediatria clín. integr Assunto da revista: ODONTOLOGIA Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Brasil

Texto completo: 1 Base de dados: BBO / LILACS Assunto principal: Remineralização Dentária / Cremes Dentais / Materiais Biomédicos e Odontológicos / Técnicas In Vitro / Fluoretos Tipo de estudo: Clinical_trials / Evaluation_studies Limite: Humans País/Região como assunto: America do sul / Brasil Idioma: En Revista: Pesqui. bras. odontopediatria clín. integr Assunto da revista: ODONTOLOGIA Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Brasil